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Conference Paper: In vivo diffusion tensor imaging of chronic spinal cord compression in rat model

TitleIn vivo diffusion tensor imaging of chronic spinal cord compression in rat model
Authors
KeywordsAxial diffusivity
Cervical myelopathy
DTI
MRI
Radial diffusivity
Spinal cord compression
Issue Date2009
PublisherIEEE. The Journal's web site is located at http://www.ieeexplore.ieee.org/xpl/conhome.jsp?punumber=1000269
Citation
The 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2009), Minneapolis, MN., 3-6 September 2009. In Proceedings of the 31st EMBC, 2009, p. 2715-2718 How to Cite?
AbstractChronic spinal cord compression induced cervical myelopathy is a comon cause of spinal cord dysfunction. The exact mechanisms of underlying progressive cell death remain to be elucidated. In this study, in vivo diffusion tensor imaging (DTI) has been applied to investigate the microstructural changes of white matter (WM) in this neurodegenerative disease. Compared with conventional MRI techniques, DTI is believed to be more specific to pathological changes. Radial diffusivity (λ⊥) is higher in the ipilesional region, suggesting demyelination or axonal degradation may occur after prolonged compression. Near the epicenter of lesion, axial diffusivity (λ∥) is lower. Also, caudal-rostral asymmetry has been observed in λ∥. Feasibility of using DTI to detect microstructural changes in chronic disease has been demonstrated. ©2009 IEEE.
DescriptionTheme: Engineering the Future of Biomedicine
Persistent Identifierhttp://hdl.handle.net/10722/129643
ISSN
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorCheung, MMen_HK
dc.contributor.authorLi, DTHen_HK
dc.contributor.authorHui, ESen_HK
dc.contributor.authorFan, Sen_HK
dc.contributor.authorDing, AYen_HK
dc.contributor.authorHu, Yen_HK
dc.contributor.authorWu, EXen_HK
dc.date.accessioned2010-12-23T08:40:39Z-
dc.date.available2010-12-23T08:40:39Z-
dc.date.issued2009en_HK
dc.identifier.citationThe 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2009), Minneapolis, MN., 3-6 September 2009. In Proceedings of the 31st EMBC, 2009, p. 2715-2718en_HK
dc.identifier.issn1557-170Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/129643-
dc.descriptionTheme: Engineering the Future of Biomedicine-
dc.description.abstractChronic spinal cord compression induced cervical myelopathy is a comon cause of spinal cord dysfunction. The exact mechanisms of underlying progressive cell death remain to be elucidated. In this study, in vivo diffusion tensor imaging (DTI) has been applied to investigate the microstructural changes of white matter (WM) in this neurodegenerative disease. Compared with conventional MRI techniques, DTI is believed to be more specific to pathological changes. Radial diffusivity (λ⊥) is higher in the ipilesional region, suggesting demyelination or axonal degradation may occur after prolonged compression. Near the epicenter of lesion, axial diffusivity (λ∥) is lower. Also, caudal-rostral asymmetry has been observed in λ∥. Feasibility of using DTI to detect microstructural changes in chronic disease has been demonstrated. ©2009 IEEE.en_HK
dc.languageengen_US
dc.publisherIEEE. The Journal's web site is located at http://www.ieeexplore.ieee.org/xpl/conhome.jsp?punumber=1000269-
dc.relation.ispartofProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2009en_HK
dc.rightsIEEE Engineering in Medicine and Biology Society. Conference Proceedings. Copyright © IEEE.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rights©2009 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.-
dc.subjectAxial diffusivityen_HK
dc.subjectCervical myelopathyen_HK
dc.subjectDTIen_HK
dc.subjectMRIen_HK
dc.subjectRadial diffusivityen_HK
dc.subjectSpinal cord compressionen_HK
dc.subject.meshAnimalsen_HK
dc.subject.meshBrain - pathologyen_HK
dc.subject.meshBrain Mapping - methodsen_HK
dc.subject.meshDiffusionen_HK
dc.subject.meshDiffusion Magnetic Resonance Imaging - instrumentation - methodsen_HK
dc.subject.meshDiffusion Tensor Imaging - instrumentation - methodsen_HK
dc.subject.meshImage Processing, Computer-Assisteden_HK
dc.subject.meshNeurodegenerative Diseases - pathologyen_HK
dc.subject.meshRatsen_HK
dc.subject.meshRats, Sprague-Dawleyen_HK
dc.subject.meshSpinal Cord - pathologyen_HK
dc.subject.meshSpinal Cord Compression - pathologyen_HK
dc.titleIn vivo diffusion tensor imaging of chronic spinal cord compression in rat modelen_HK
dc.typeConference_Paperen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1557-170X&volume=&spage=2715&epage=2718&date=2009&atitle=In+vivo+diffusion+tensor+imaging+of+chronic+spinal+cord+compression+in+rat+model-
dc.identifier.emailHu, Y:yhud@hku.hken_HK
dc.identifier.emailWu, EX:ewu1@hkucc.hku.hken_HK
dc.identifier.authorityHu, Y=rp00432en_HK
dc.identifier.authorityWu, EX=rp00193en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1109/IEMBS.2009.5333389en_HK
dc.identifier.pmid19964039-
dc.identifier.scopuseid_2-s2.0-77951012053en_HK
dc.identifier.hkuros178151en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77951012053&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.spage2715en_HK
dc.identifier.epage2718en_HK
dc.identifier.isiWOS:000280543602043-
dc.publisher.placeUnited Statesen_HK
dc.description.otherThe 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2009), Minneapolis, MN., 3-6 September 2009. In Proceedings of the 31st EMBC, 2009, p. 2715-2718-
dc.identifier.scopusauthoridCheung, MM=24333907800en_HK
dc.identifier.scopusauthoridLi, DTH=35746374500en_HK
dc.identifier.scopusauthoridHui, ES=16175117100en_HK
dc.identifier.scopusauthoridFan, S=36514618100en_HK
dc.identifier.scopusauthoridDing, AY=35745892100en_HK
dc.identifier.scopusauthoridHu, Y=7407116091en_HK
dc.identifier.scopusauthoridWu, EX=7202128034en_HK

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