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Conference Paper: Metabolite profiling of mild hypothermia by 1H-MRS
| Title | Metabolite profiling of mild hypothermia by 1H-MRS |
|---|---|
| Authors | |
| Issue Date | 2010 |
| Citation | The ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden, 1-7 May 2010. How to Cite? |
| Abstract | Hypothermia has a profound effect on the protection of brain. However, its exact mechanisms remain to be elucidated. Hypothermia induces changes in brain metabolites. 1H-MRS can detect changes in metabolites and hence help us to have a better understanding of hypothermia. Our data shows changes in several metabolites in the cortex and thalamus. These metabolites are associated with cascade of events that lead to neuroprotection and thermoregulation, which are similar to ex vivo and microdialysis findings. This real time and site specific monitor of metabolites at 7T gives insight into how hypothermia protects the brain from various insults. |
| Description | Posters - MRS of Animal Brain: No. 4525 |
| Persistent Identifier | http://hdl.handle.net/10722/129640 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Chan, KWY | en_US |
| dc.contributor.author | Chow, AMK | en_US |
| dc.contributor.author | Xiao, L | en_US |
| dc.contributor.author | Wu, EX | en_US |
| dc.date.accessioned | 2010-12-23T08:40:38Z | - |
| dc.date.available | 2010-12-23T08:40:38Z | - |
| dc.date.issued | 2010 | en_US |
| dc.identifier.citation | The ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden, 1-7 May 2010. | en_US |
| dc.identifier.uri | http://hdl.handle.net/10722/129640 | - |
| dc.description | Posters - MRS of Animal Brain: No. 4525 | - |
| dc.description.abstract | Hypothermia has a profound effect on the protection of brain. However, its exact mechanisms remain to be elucidated. Hypothermia induces changes in brain metabolites. 1H-MRS can detect changes in metabolites and hence help us to have a better understanding of hypothermia. Our data shows changes in several metabolites in the cortex and thalamus. These metabolites are associated with cascade of events that lead to neuroprotection and thermoregulation, which are similar to ex vivo and microdialysis findings. This real time and site specific monitor of metabolites at 7T gives insight into how hypothermia protects the brain from various insults. | - |
| dc.language | eng | en_US |
| dc.relation.ispartof | ISMRM-ESMRMB Joint Annual Meeting | - |
| dc.title | Metabolite profiling of mild hypothermia by 1H-MRS | en_US |
| dc.type | Conference_Paper | en_US |
| dc.identifier.email | Chan, KWY: kannie@graduate.hku.hk | en_US |
| dc.identifier.email | Chow, AMK: aprilcmk@hkusua.hku.hk | - |
| dc.identifier.email | Wu, EX: ewu@eee.hku.hk | - |
| dc.description.nature | postprint | - |
| dc.identifier.hkuros | 178223 | en_US |