Conference Paper: Metabolite profiling of mild hypothermia by 1H-MRS

TitleMetabolite profiling of mild hypothermia by 1H-MRS
Authors
Issue Date2010
Citation
The ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden, 1-7 May 2010. How to Cite?
AbstractHypothermia has a profound effect on the protection of brain. However, its exact mechanisms remain to be elucidated. Hypothermia induces changes in brain metabolites. 1H-MRS can detect changes in metabolites and hence help us to have a better understanding of hypothermia. Our data shows changes in several metabolites in the cortex and thalamus. These metabolites are associated with cascade of events that lead to neuroprotection and thermoregulation, which are similar to ex vivo and microdialysis findings. This real time and site specific monitor of metabolites at 7T gives insight into how hypothermia protects the brain from various insults.
DescriptionPosters - MRS of Animal Brain: No. 4525
Persistent Identifierhttp://hdl.handle.net/10722/129640

 

DC FieldValueLanguage
dc.contributor.authorChan, KWYen_US
dc.contributor.authorChow, AMKen_US
dc.contributor.authorXiao, Len_US
dc.contributor.authorWu, EXen_US
dc.date.accessioned2010-12-23T08:40:38Z-
dc.date.available2010-12-23T08:40:38Z-
dc.date.issued2010en_US
dc.identifier.citationThe ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden, 1-7 May 2010.en_US
dc.identifier.urihttp://hdl.handle.net/10722/129640-
dc.descriptionPosters - MRS of Animal Brain: No. 4525-
dc.description.abstractHypothermia has a profound effect on the protection of brain. However, its exact mechanisms remain to be elucidated. Hypothermia induces changes in brain metabolites. 1H-MRS can detect changes in metabolites and hence help us to have a better understanding of hypothermia. Our data shows changes in several metabolites in the cortex and thalamus. These metabolites are associated with cascade of events that lead to neuroprotection and thermoregulation, which are similar to ex vivo and microdialysis findings. This real time and site specific monitor of metabolites at 7T gives insight into how hypothermia protects the brain from various insults.-
dc.languageengen_US
dc.relation.ispartofISMRM-ESMRMB Joint Annual Meeting-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleMetabolite profiling of mild hypothermia by 1H-MRSen_US
dc.typeConference_Paperen_US
dc.identifier.emailChan, KWY: kannie@graduate.hku.hken_US
dc.identifier.emailChow, AMK: aprilcmk@hkusua.hku.hk-
dc.identifier.emailWu, EX: ewu@eee.hku.hk-
dc.description.naturepostprint-
dc.identifier.hkuros178223en_US

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