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Article: A socio-biological explanation for social disparities in non-communicable chronic diseases: The product of history?

TitleA socio-biological explanation for social disparities in non-communicable chronic diseases: The product of history?
Authors
Issue Date2010
PublisherB M J Publishing Group. The Journal's web site is located at http://jech.bmjjournals.com/
Citation
Journal Of Epidemiology And Community Health, 2010, v. 64 n. 11, p. 941-949 How to Cite?
AbstractThis study places social disparities in the major non-communicable chronic diseases within their global economic and historical contexts. Rapid economic transition outside the developed world provides a unique opportunity to re-examine the origins of, and biological mechanisms driving, social disparities. Gaps in prevailing theories focusing on material resources, civic infrastructure and social structure are identified. Using longstanding experimental evidence and epigenetic theories, it is suggested that exposure to economic development over generations (ie, improved living conditions over historical time) could by acting on different biological axes (somatotrophic and gonadotrophic) generate specific patterns of social disparities. Moreover, these same processes could initially generate a transient epidemic of diabetes as well as a permanent increase in male risk of premature ischaemic heart disease. As such, this study demonstrates the importance of context, and implies that current evidence from the developed world may be largely uninformative for preventing or mitigating social disparities in non-communicable chronic diseases elsewhere, suggesting research efforts should be focused on developing countries.
Persistent Identifierhttp://hdl.handle.net/10722/129484
ISSN
2015 Impact Factor: 3.865
2015 SCImago Journal Rankings: 1.890
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorSchooling, CMen_HK
dc.contributor.authorLeung, GMen_HK
dc.date.accessioned2010-12-23T08:37:51Z-
dc.date.available2010-12-23T08:37:51Z-
dc.date.issued2010en_HK
dc.identifier.citationJournal Of Epidemiology And Community Health, 2010, v. 64 n. 11, p. 941-949en_HK
dc.identifier.issn0143-005Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/129484-
dc.description.abstractThis study places social disparities in the major non-communicable chronic diseases within their global economic and historical contexts. Rapid economic transition outside the developed world provides a unique opportunity to re-examine the origins of, and biological mechanisms driving, social disparities. Gaps in prevailing theories focusing on material resources, civic infrastructure and social structure are identified. Using longstanding experimental evidence and epigenetic theories, it is suggested that exposure to economic development over generations (ie, improved living conditions over historical time) could by acting on different biological axes (somatotrophic and gonadotrophic) generate specific patterns of social disparities. Moreover, these same processes could initially generate a transient epidemic of diabetes as well as a permanent increase in male risk of premature ischaemic heart disease. As such, this study demonstrates the importance of context, and implies that current evidence from the developed world may be largely uninformative for preventing or mitigating social disparities in non-communicable chronic diseases elsewhere, suggesting research efforts should be focused on developing countries.en_HK
dc.languageengen_US
dc.publisherB M J Publishing Group. The Journal's web site is located at http://jech.bmjjournals.com/en_HK
dc.relation.ispartofJournal of Epidemiology and Community Healthen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleA socio-biological explanation for social disparities in non-communicable chronic diseases: The product of history?en_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0143-005X&volume=64&issue=11&spage=941&epage=949&date=2010&atitle=A+socio-biological+explanation+for+social+disparities+in+non-communicable+chronic+diseases:+The+product+of+history?-
dc.identifier.emailSchooling, CM:cms1@hkucc.hku.hken_HK
dc.identifier.emailLeung, GM:gmleung@hku.hken_HK
dc.identifier.authoritySchooling, CM=rp00504en_HK
dc.identifier.authorityLeung, GM=rp00460en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1136/jech.2008.086553en_HK
dc.identifier.pmid20515893-
dc.identifier.scopuseid_2-s2.0-77953808935en_HK
dc.identifier.hkuros183424en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77953808935&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume64en_HK
dc.identifier.issue11en_HK
dc.identifier.spage941en_HK
dc.identifier.epage949en_HK
dc.identifier.isiWOS:000283176000004-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridSchooling, CM=12808565000en_HK
dc.identifier.scopusauthoridLeung, GM=7007159841en_HK

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