File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Physical activity, adiposity, and diabetes risk in middle-aged and older Chinese population: The Guangzhou Biobank cohort study

TitlePhysical activity, adiposity, and diabetes risk in middle-aged and older Chinese population: The Guangzhou Biobank cohort study
Authors
Issue Date2010
PublisherAmerican Diabetes Association. The Journal's web site is located at http://diabetes.diabetesjournals.org/
Citation
Diabetes Care, 2010, v. 33 n. 11, p. 2342-2348 How to Cite?
AbstractOBJECTIVE- Physical activity may modify the association of adiposity with type 2 diabetes. We investigated the independent and joint association of adiposity and physical activity with fasting plasma glucose, impaired fasting glucose, and type 2 diabetes in a Chinese population. RESEARCH DESIGN AND METHODS- Middle-aged and older Chinese (n = 28,946, ≥50 years, 72.4%women) from the Guangzhou Biobank Cohort Study were examined in 2003-2008. Multivariable regression was used in a cross-sectional analysis. RESULTS- BMI, waist circumference, and waist-to-hip ratio (WHR) were positively associated with type 2 diabetes after multiple adjustment, most strongly for WHR with odds ratio (OR) of 3.99 (95% CI 3.60-4.42) for highest compared with lowest tertile. Lack of moderate-to-vigorous physical activity, but not walking, was associated with diabetes with an OR of 1.29 (1.17-1.41). The association of moderate-to-vigorous activity with fasting glucose varied with WHR tertiles (P=0.01 for interaction). Within the highWHRtertile, participants who had a lack of moderate-to-vigorous activity had an OR of 3.87 (3.22-4.65) for diabetes, whereas those who were active had an OR of 2.94 (2.41-3.59). CONCLUSIONS- In this population, WHR was a better measure of adiposity-related diabetes risk than BMI or waist circumference. Higher moderate-to-vigorous activity was associated with lower diabetes risk, especially in abdominally obese individuals. © 2010 by the American Diabetes Association.
Persistent Identifierhttp://hdl.handle.net/10722/129478
ISSN
2015 Impact Factor: 8.934
2015 SCImago Journal Rankings: 5.827
PubMed Central ID
ISI Accession Number ID
Funding AgencyGrant Number
University of Hong Kong Foundation for Education Development and Research
Guangzhou Public Health Bureau
Guangzhou Science and Technology Bureau
Graduate School for Health Research at the University of Groningen (SHARE)
University of Birmingham
Clinical Trial Service Unit of the University of Oxford
Funding Information:

This study was supported by the University of Hong Kong Foundation for Education Development and Research, the Guangzhou Public Health Bureau, the Guangzhou Science and Technology Bureau, Graduate School for Health Research at the University of Groningen (SHARE), and the University of Birmingham.

References

 

DC FieldValueLanguage
dc.contributor.authorQin, Len_HK
dc.contributor.authorCorpeleijn, Een_HK
dc.contributor.authorJiang, Cen_HK
dc.contributor.authorThomas, GNen_HK
dc.contributor.authorSchooling, CMen_HK
dc.contributor.authorZhang, Wen_HK
dc.contributor.authorCheng, KKen_HK
dc.contributor.authorLeung, GMen_HK
dc.contributor.authorStolk, RPen_HK
dc.contributor.authorLam, THen_HK
dc.date.accessioned2010-12-23T08:37:48Z-
dc.date.available2010-12-23T08:37:48Z-
dc.date.issued2010en_HK
dc.identifier.citationDiabetes Care, 2010, v. 33 n. 11, p. 2342-2348en_HK
dc.identifier.issn0149-5992en_HK
dc.identifier.urihttp://hdl.handle.net/10722/129478-
dc.description.abstractOBJECTIVE- Physical activity may modify the association of adiposity with type 2 diabetes. We investigated the independent and joint association of adiposity and physical activity with fasting plasma glucose, impaired fasting glucose, and type 2 diabetes in a Chinese population. RESEARCH DESIGN AND METHODS- Middle-aged and older Chinese (n = 28,946, ≥50 years, 72.4%women) from the Guangzhou Biobank Cohort Study were examined in 2003-2008. Multivariable regression was used in a cross-sectional analysis. RESULTS- BMI, waist circumference, and waist-to-hip ratio (WHR) were positively associated with type 2 diabetes after multiple adjustment, most strongly for WHR with odds ratio (OR) of 3.99 (95% CI 3.60-4.42) for highest compared with lowest tertile. Lack of moderate-to-vigorous physical activity, but not walking, was associated with diabetes with an OR of 1.29 (1.17-1.41). The association of moderate-to-vigorous activity with fasting glucose varied with WHR tertiles (P=0.01 for interaction). Within the highWHRtertile, participants who had a lack of moderate-to-vigorous activity had an OR of 3.87 (3.22-4.65) for diabetes, whereas those who were active had an OR of 2.94 (2.41-3.59). CONCLUSIONS- In this population, WHR was a better measure of adiposity-related diabetes risk than BMI or waist circumference. Higher moderate-to-vigorous activity was associated with lower diabetes risk, especially in abdominally obese individuals. © 2010 by the American Diabetes Association.en_HK
dc.languageengen_US
dc.publisherAmerican Diabetes Association. The Journal's web site is located at http://diabetes.diabetesjournals.org/en_HK
dc.relation.ispartofDiabetes Careen_HK
dc.subject.meshAdiposity - physiologyen_HK
dc.subject.meshAgeden_HK
dc.subject.meshAsian Continental Ancestry Groupen_HK
dc.subject.meshBlood Glucose - metabolismen_HK
dc.subject.meshBody Mass Indexen_HK
dc.subject.meshChina - epidemiologyen_HK
dc.subject.meshCross-Sectional Studiesen_HK
dc.subject.meshDiabetes Mellitus, Type 2 - epidemiologyen_HK
dc.subject.meshFasting - blooden_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshMotor Activity - physiologyen_HK
dc.subject.meshMultivariate Analysisen_HK
dc.subject.meshRisk Factorsen_HK
dc.subject.meshWaist-Hip Ratioen_HK
dc.titlePhysical activity, adiposity, and diabetes risk in middle-aged and older Chinese population: The Guangzhou Biobank cohort studyen_HK
dc.typeArticleen_HK
dc.identifier.emailSchooling, CM:cms1@hkucc.hku.hken_HK
dc.identifier.emailLeung, GM:gmleung@hku.hken_HK
dc.identifier.emailLam, TH:hrmrlth@hkucc.hku.hken_HK
dc.identifier.authoritySchooling, CM=rp00504en_HK
dc.identifier.authorityLeung, GM=rp00460en_HK
dc.identifier.authorityLam, TH=rp00326en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.2337/dc10-0369en_HK
dc.identifier.pmid20713687-
dc.identifier.pmcidPMC2963492-
dc.identifier.scopuseid_2-s2.0-79951700299en_HK
dc.identifier.hkuros183421en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79951700299&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume33en_HK
dc.identifier.issue11en_HK
dc.identifier.spage2342en_HK
dc.identifier.epage2348en_HK
dc.identifier.isiWOS:000284516400010-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridQin, L=36017549000en_HK
dc.identifier.scopusauthoridCorpeleijn, E=14051639400en_HK
dc.identifier.scopusauthoridJiang, C=10639500500en_HK
dc.identifier.scopusauthoridThomas, GN=35465269900en_HK
dc.identifier.scopusauthoridSchooling, CM=12808565000en_HK
dc.identifier.scopusauthoridZhang, W=14833531400en_HK
dc.identifier.scopusauthoridCheng, KK=7402997800en_HK
dc.identifier.scopusauthoridLeung, GM=7007159841en_HK
dc.identifier.scopusauthoridStolk, RP=35231504800en_HK
dc.identifier.scopusauthoridLam, TH=7202522876en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats