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Article: Intra-abdominal rhizopus microsporus infection successfully treated by combined aggressive surgical, antifungal, and iron chelating therapy

TitleIntra-abdominal rhizopus microsporus infection successfully treated by combined aggressive surgical, antifungal, and iron chelating therapy
Authors
KeywordsIron chelator
Rhizopus
Zygomycosis
Issue Date2010
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.jpho-online.com
Citation
Journal Of Pediatric Hematology/Oncology, 2010, v. 32 n. 6, p. e238-e240 How to Cite?
AbstractZygomycetes are widely distributed in the environment as inhabitants of soil and decaying matter. On rare occasions, these organisms can cause invasive infections in immunocompromised hosts. As zygomycetes are resistant to most conventional antifungal agents, its infection is often fatal. We report 2 cases of unusual intra-abdominal Rhizopus microsporus infection in children with acute leukemia as a result of an unprecedented outbreak due to oral intake of contaminated allopurinol tablets and ready-to-eat food items. Among the 2 patients, one of them survived after aggressive combined surgical, antifungal (AmBisome, Caspofun-gin, and Posaconazole) and iron chelation therapy. Copyright © 2010 by Lippincott Williams & Wilkins.
Persistent Identifierhttp://hdl.handle.net/10722/129329
ISSN
2015 Impact Factor: 1.146
2015 SCImago Journal Rankings: 0.452
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorTing, JYen_HK
dc.contributor.authorChan, SYen_HK
dc.contributor.authorLung, DCen_HK
dc.contributor.authorChiChung, Aen_HK
dc.contributor.authorChiang, AKSen_HK
dc.contributor.authorHa, SYen_HK
dc.contributor.authorTsoi, NNSen_HK
dc.contributor.authorChan, GCFen_HK
dc.date.accessioned2010-12-23T08:35:23Z-
dc.date.available2010-12-23T08:35:23Z-
dc.date.issued2010en_HK
dc.identifier.citationJournal Of Pediatric Hematology/Oncology, 2010, v. 32 n. 6, p. e238-e240en_HK
dc.identifier.issn1077-4114en_HK
dc.identifier.urihttp://hdl.handle.net/10722/129329-
dc.description.abstractZygomycetes are widely distributed in the environment as inhabitants of soil and decaying matter. On rare occasions, these organisms can cause invasive infections in immunocompromised hosts. As zygomycetes are resistant to most conventional antifungal agents, its infection is often fatal. We report 2 cases of unusual intra-abdominal Rhizopus microsporus infection in children with acute leukemia as a result of an unprecedented outbreak due to oral intake of contaminated allopurinol tablets and ready-to-eat food items. Among the 2 patients, one of them survived after aggressive combined surgical, antifungal (AmBisome, Caspofun-gin, and Posaconazole) and iron chelation therapy. Copyright © 2010 by Lippincott Williams & Wilkins.en_HK
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.jpho-online.comen_HK
dc.relation.ispartofJournal of Pediatric Hematology/Oncologyen_HK
dc.subjectIron chelatoren_HK
dc.subjectRhizopusen_HK
dc.subjectZygomycosisen_HK
dc.titleIntra-abdominal rhizopus microsporus infection successfully treated by combined aggressive surgical, antifungal, and iron chelating therapyen_HK
dc.typeArticleen_HK
dc.identifier.emailChiang, AKS:chiangak@hkucc.hku.hken_HK
dc.identifier.emailChan, GCF:gcfchan@hkucc.hku.hken_HK
dc.identifier.authorityChiang, AKS=rp00403en_HK
dc.identifier.authorityChan, GCF=rp00431en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1097/MPH.0b013e3181e622bfen_HK
dc.identifier.pmid20661158en_HK
dc.identifier.scopuseid_2-s2.0-77955916824en_HK
dc.identifier.hkuros178629en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77955916824&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume32en_HK
dc.identifier.issue6en_HK
dc.identifier.spagee238en_HK
dc.identifier.epagee240en_HK
dc.identifier.isiWOS:000280666100028-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridTing, JY=36183055700en_HK
dc.identifier.scopusauthoridChan, SY=7404255845en_HK
dc.identifier.scopusauthoridLung, DC=36902110000en_HK
dc.identifier.scopusauthoridChiChung, A=36503829900en_HK
dc.identifier.scopusauthoridChiang, AKS=7101623534en_HK
dc.identifier.scopusauthoridHa, SY=7202501115en_HK
dc.identifier.scopusauthoridTsoi, NNS=36771424500en_HK
dc.identifier.scopusauthoridChan, GCF=16160154400en_HK

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