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Article: Metallomics: An integrated science for metals in biology and medicine

TitleMetallomics: An integrated science for metals in biology and medicine
Authors
Issue Date2010
PublisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/ic/
Citation
Annual Reports On The Progress Of Chemistry - Section A, 2010, v. 106, p. 20-38 How to Cite?
AbstractMetallomics and metalloproteomics are an emerging scientific area focusing on the molecular mechanisms of metal-dependent life processes and the entirety of metal and metalloid species within a cell or tissue/organ. Metallomics is also a part of functional proteomics, complements metabonomics and structural geonomics of metalloproteins. This review summarizes the recent progress of metallomics with a focus on analytical techniques capable of high-throughput quantification, distribution, speciation, identification and structural characterisation. The applications of these advanced analytical methods in the identification of metallo-/phosphor-/seleno-proteins, probing of structure-function relationships of metalloproteins, and the study of metallodrugs will be selectively outlined. © 2010 The Royal Society of Chemistry.
Persistent Identifierhttp://hdl.handle.net/10722/129114
ISSN
2015 SCImago Journal Rankings: 0.333
References

 

DC FieldValueLanguage
dc.contributor.authorSun, Hen_HK
dc.contributor.authorChai, ZFen_HK
dc.date.accessioned2010-12-23T08:32:43Z-
dc.date.available2010-12-23T08:32:43Z-
dc.date.issued2010en_HK
dc.identifier.citationAnnual Reports On The Progress Of Chemistry - Section A, 2010, v. 106, p. 20-38en_HK
dc.identifier.issn0260-1818en_HK
dc.identifier.urihttp://hdl.handle.net/10722/129114-
dc.description.abstractMetallomics and metalloproteomics are an emerging scientific area focusing on the molecular mechanisms of metal-dependent life processes and the entirety of metal and metalloid species within a cell or tissue/organ. Metallomics is also a part of functional proteomics, complements metabonomics and structural geonomics of metalloproteins. This review summarizes the recent progress of metallomics with a focus on analytical techniques capable of high-throughput quantification, distribution, speciation, identification and structural characterisation. The applications of these advanced analytical methods in the identification of metallo-/phosphor-/seleno-proteins, probing of structure-function relationships of metalloproteins, and the study of metallodrugs will be selectively outlined. © 2010 The Royal Society of Chemistry.en_HK
dc.languageengen_US
dc.publisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/ic/en_HK
dc.relation.ispartofAnnual Reports on the Progress of Chemistry - Section Aen_HK
dc.titleMetallomics: An integrated science for metals in biology and medicineen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0260-1818&volume=106&spage=20&epage=38&date=2010&atitle=Metallomics:+an+integrated+science+for+metals+in+biology+and+medicine-
dc.identifier.emailSun, H:hsun@hkucc.hku.hken_HK
dc.identifier.authoritySun, H=rp00777en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1039/b920672hen_HK
dc.identifier.scopuseid_2-s2.0-77954736033en_HK
dc.identifier.hkuros177254en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77954736033&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume106en_HK
dc.identifier.spage20en_HK
dc.identifier.epage38en_HK
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridSun, H=7404827446en_HK
dc.identifier.scopusauthoridChai, ZF=7102022658en_HK

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