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- Publisher Website: 10.1111/j.1601-0825.2009.01628.x
- Scopus: eid_2-s2.0-77949596806
- PMID: 19758406
- WOS: WOS:000275644600004
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Article: Immune reconstitution inflammatory syndrome after highly active antiretroviral therapy: A review
Title | Immune reconstitution inflammatory syndrome after highly active antiretroviral therapy: A review |
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Authors | |
Keywords | AIDS HAART HIV Immune reconstitution inflammatory syndrome Oral manifestations |
Issue Date | 2010 |
Publisher | Wiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1354-523X&site=1 |
Citation | Oral Diseases, 2010, v. 16 n. 3, p. 248-256 How to Cite? |
Abstract | The use of highly active antiretroviral therapy (HAART) in the management of human immunodeficiency virus (HIV) restores immune responses against pathogens and has greatly decreased mortality. However, in about 25% to 35% of patients receiving HAART, the reconstituted immune system leads to a pathological inflammatory response, commonly known as immune reconstitution inflammatory syndrome (IRIS), which causes substantial short-term morbidity or even mortality. Although we have gleaned some knowledge on IRIS in the past few years, a number of unanswered questions remain. In this review, we discuss the definition, diagnostic criteria, pathogenesis, risk factors, clinical spectrum including oral manifestations, and management of IRIS. © 2009 John Wiley & Sons A/S. |
Persistent Identifier | http://hdl.handle.net/10722/129080 |
ISSN | 2023 Impact Factor: 2.9 2023 SCImago Journal Rankings: 0.895 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Tsang, CSP | en_HK |
dc.contributor.author | Samaranayake, LP | en_HK |
dc.date.accessioned | 2010-12-23T08:32:09Z | - |
dc.date.available | 2010-12-23T08:32:09Z | - |
dc.date.issued | 2010 | en_HK |
dc.identifier.citation | Oral Diseases, 2010, v. 16 n. 3, p. 248-256 | en_HK |
dc.identifier.issn | 1354-523X | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/129080 | - |
dc.description.abstract | The use of highly active antiretroviral therapy (HAART) in the management of human immunodeficiency virus (HIV) restores immune responses against pathogens and has greatly decreased mortality. However, in about 25% to 35% of patients receiving HAART, the reconstituted immune system leads to a pathological inflammatory response, commonly known as immune reconstitution inflammatory syndrome (IRIS), which causes substantial short-term morbidity or even mortality. Although we have gleaned some knowledge on IRIS in the past few years, a number of unanswered questions remain. In this review, we discuss the definition, diagnostic criteria, pathogenesis, risk factors, clinical spectrum including oral manifestations, and management of IRIS. © 2009 John Wiley & Sons A/S. | en_HK |
dc.language | eng | en_US |
dc.publisher | Wiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1354-523X&site=1 | en_HK |
dc.relation.ispartof | Oral Diseases | en_HK |
dc.rights | The definitive version is available at www3.interscience.wiley.com | - |
dc.subject | AIDS | en_HK |
dc.subject | HAART | en_HK |
dc.subject | HIV | en_HK |
dc.subject | Immune reconstitution inflammatory syndrome | en_HK |
dc.subject | Oral manifestations | en_HK |
dc.subject.mesh | AIDS-Related Opportunistic Infections - complications | - |
dc.subject.mesh | Antiretroviral Therapy, Highly Active - adverse effects | - |
dc.subject.mesh | Candidiasis, Oral - complications | - |
dc.subject.mesh | Immune Reconstitution Inflammatory Syndrome - complications - diagnosis - etiology - therapy | - |
dc.subject.mesh | Mouth Diseases - complications | - |
dc.title | Immune reconstitution inflammatory syndrome after highly active antiretroviral therapy: A review | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1354-523X&volume=16&issue=3&spage=248&epage=256&date=2010&atitle=Immune+reconstitution+inflammatory+syndrome+after+highly+active+antiretroviral+therapy:+a+review | - |
dc.identifier.email | Tsang, CSP:csptsang@hkucc.hku.hk | en_HK |
dc.identifier.email | Samaranayake, LP:lakshman@hku.hk | en_HK |
dc.identifier.authority | Tsang, CSP=rp00026 | en_HK |
dc.identifier.authority | Samaranayake, LP=rp00023 | en_HK |
dc.description.nature | postprint | - |
dc.identifier.doi | 10.1111/j.1601-0825.2009.01628.x | en_HK |
dc.identifier.pmid | 19758406 | - |
dc.identifier.scopus | eid_2-s2.0-77949596806 | en_HK |
dc.identifier.hkuros | 177035 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-77949596806&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 16 | en_HK |
dc.identifier.issue | 3 | en_HK |
dc.identifier.spage | 248 | en_HK |
dc.identifier.epage | 256 | en_HK |
dc.identifier.eissn | 1601-0825 | - |
dc.identifier.isi | WOS:000275644600004 | - |
dc.publisher.place | United States | en_HK |
dc.identifier.scopusauthorid | Tsang, CSP=7202936002 | en_HK |
dc.identifier.scopusauthorid | Samaranayake, LP=7102761002 | en_HK |
dc.identifier.citeulike | 6885113 | - |
dc.identifier.issnl | 1354-523X | - |