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Article: Effect of Bio-Oss ® Collagen and Collagen matrix on bone formation

TitleEffect of Bio-Oss ® Collagen and Collagen matrix on bone formation
Authors
KeywordsBio-Oss ® Collagen
Bone graft
Collagen
Issue Date2010
PublisherBentham Open. The Journal's web site is located at http://www.bentham.org/open/tobej/index.htm
Citation
Open Biomedical Engineering Journal, 2010, v. 4, p. 71-76 How to Cite?
AbstractObjective: to compare the amount of new bone produced by Bio-Oss ® Collagen to that produced by collagen matrix in vivo. Method: eighteen bone defects, 5mm by 10mm were created in the parietal bone of 9 New Zealand White rabbits. 6 defects were grafted with Bio-Oss ® Collagen. 6 defects were grafted with collagen matrix alone (positive control) and 6 were left empty (negative control). Animals were killed on day 14 and the defects were dissected and prepared for histological assessment. Quantitative analysis of new bone formation was made on 100 sections (50 sections for each group) using image analysis. Results: A total of 339% more new bone was present in defects grafted with Bio-Oss ® Collagen than those grafted with collagen matrix (positive control). No bone was formed in the negative control group. Conclusion: Bio-Oss ® Collagen has the effect of stimulating new bone formation locally compared with collagen matrix in vivo. Bio-Oss ® Collagen may be utilized as a bone graft material. © Wong and Rabie; Licensee Bentham Open.
Persistent Identifierhttp://hdl.handle.net/10722/129069
ISSN
2015 SCImago Journal Rankings: 0.278
PubMed Central ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, RWKen_HK
dc.contributor.authorRabie, ABMen_HK
dc.date.accessioned2010-12-23T08:32:03Z-
dc.date.available2010-12-23T08:32:03Z-
dc.date.issued2010en_HK
dc.identifier.citationOpen Biomedical Engineering Journal, 2010, v. 4, p. 71-76en_HK
dc.identifier.issn1874-1207en_HK
dc.identifier.urihttp://hdl.handle.net/10722/129069-
dc.description.abstractObjective: to compare the amount of new bone produced by Bio-Oss ® Collagen to that produced by collagen matrix in vivo. Method: eighteen bone defects, 5mm by 10mm were created in the parietal bone of 9 New Zealand White rabbits. 6 defects were grafted with Bio-Oss ® Collagen. 6 defects were grafted with collagen matrix alone (positive control) and 6 were left empty (negative control). Animals were killed on day 14 and the defects were dissected and prepared for histological assessment. Quantitative analysis of new bone formation was made on 100 sections (50 sections for each group) using image analysis. Results: A total of 339% more new bone was present in defects grafted with Bio-Oss ® Collagen than those grafted with collagen matrix (positive control). No bone was formed in the negative control group. Conclusion: Bio-Oss ® Collagen has the effect of stimulating new bone formation locally compared with collagen matrix in vivo. Bio-Oss ® Collagen may be utilized as a bone graft material. © Wong and Rabie; Licensee Bentham Open.en_HK
dc.languageengen_US
dc.publisherBentham Open. The Journal's web site is located at http://www.bentham.org/open/tobej/index.htmen_HK
dc.relation.ispartofOpen Biomedical Engineering Journalen_HK
dc.subjectBio-Oss ® Collagenen_HK
dc.subjectBone graften_HK
dc.subjectCollagenen_HK
dc.titleEffect of Bio-Oss ® Collagen and Collagen matrix on bone formationen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1874-1207&volume=4&spage=71&epage=76&date=2010&atitle=Effect+of+Bio-Oss®+Collagen+and+Collagen+Matrix+on+Bone+Formation-
dc.identifier.emailRabie, ABM: rabie@hku.hken_HK
dc.identifier.authorityRabie, ABM=rp00029en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.2174/1874120701004010071en_HK
dc.identifier.pmid20461225-
dc.identifier.pmcidPMC2866303-
dc.identifier.scopuseid_2-s2.0-78650944353en_HK
dc.identifier.hkuros183269en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-78650944353&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume4en_HK
dc.identifier.spage71en_HK
dc.identifier.epage76en_HK
dc.publisher.placeNetherlandsen_HK
dc.identifier.scopusauthoridWong, RWK=36642905800en_HK
dc.identifier.scopusauthoridRabie, ABM=7007172734en_HK

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