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Article: Synthesis, in vitro hydroxyapatite forming ability, and cytocompatibility of strontium silicate powders

TitleSynthesis, in vitro hydroxyapatite forming ability, and cytocompatibility of strontium silicate powders
Authors
KeywordsCytocompatibility
Hydroxyapatite forming ability
Hydroxyapatite forming ability
Issue Date2010
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0021-9304:1/
Citation
Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2010, v. 93 n. 1, p. 252-257 How to Cite?
AbstractPhase-pure strontium silicate (SrSiO(3)) powders were synthesized by chemical precipitation method. In vitro bioactivity of the powders were evaluated by examining the hydroxyapatite forming ability on their surface soaking simulated body fluid for various periods. The results showed that SrSiO(3) could induce hydroxy carbonate apatite formation after soaking for 7 days. Both L929 and rabbit bone marrow stromal cells (rMSCs) were used to test the in vitro cytocompatibility of SrSiO(3). L929 culture experiment showed that the ionic product of SrSiO(3) did not exhibit cytotoxicity except at high ion concentrations (Si 3.75 mM and Sr 0.12 mM). Moreover, at certain ion concentrations (Si 1.87-0.12 mM and Sr 0.12-3.75 x 10(-3) mM), the ionic product of SrSiO(3) stimulated the proliferation of rMSCs. All the results indicated that SrSiO(3) might be used as a new bioactive material for bone regeneration applications. © 2010 Wiley Periodicals, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/129056
ISSN
2015 Impact Factor: 2.881
2015 SCImago Journal Rankings: 0.784
ISI Accession Number ID
Funding AgencyGrant Number
Science and Technology Commission of Shanghai Municipality08JC1420800
09JC1415500
People's Republic of China2005CB522704
Natural Science Foundation of China30730034
Funding Information:

Contract grant sponsor: Science and Technology Commission of Shanghai Municipality; contract grant numbers: 08JC1420800, 09JC1415500

 

DC FieldValueLanguage
dc.contributor.authorZhang, Men_US
dc.contributor.authorZhai, Wen_US
dc.contributor.authorLin, Ken_US
dc.contributor.authorPan, Hen_US
dc.contributor.authorLu, WWen_US
dc.contributor.authorChang, Jen_US
dc.date.accessioned2010-12-23T08:31:57Z-
dc.date.available2010-12-23T08:31:57Z-
dc.date.issued2010en_US
dc.identifier.citationJournal of Biomedical Materials Research Part B: Applied Biomaterials, 2010, v. 93 n. 1, p. 252-257en_US
dc.identifier.issn1552-4973-
dc.identifier.urihttp://hdl.handle.net/10722/129056-
dc.description.abstractPhase-pure strontium silicate (SrSiO(3)) powders were synthesized by chemical precipitation method. In vitro bioactivity of the powders were evaluated by examining the hydroxyapatite forming ability on their surface soaking simulated body fluid for various periods. The results showed that SrSiO(3) could induce hydroxy carbonate apatite formation after soaking for 7 days. Both L929 and rabbit bone marrow stromal cells (rMSCs) were used to test the in vitro cytocompatibility of SrSiO(3). L929 culture experiment showed that the ionic product of SrSiO(3) did not exhibit cytotoxicity except at high ion concentrations (Si 3.75 mM and Sr 0.12 mM). Moreover, at certain ion concentrations (Si 1.87-0.12 mM and Sr 0.12-3.75 x 10(-3) mM), the ionic product of SrSiO(3) stimulated the proliferation of rMSCs. All the results indicated that SrSiO(3) might be used as a new bioactive material for bone regeneration applications. © 2010 Wiley Periodicals, Inc.-
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0021-9304:1/-
dc.relation.ispartofJournal of Biomedical Materials Research Part B: Applied Biomaterialsen_US
dc.rightsJournal of Biomedical Materials Research Part B: Applied Biomaterials. Copyright © John Wiley & Sons, Inc.-
dc.subjectCytocompatibility-
dc.subjectHydroxyapatite forming ability-
dc.subjectHydroxyapatite forming ability-
dc.subject.meshBody Fluids - metabolism-
dc.subject.meshBone Substitutes - chemical synthesis - chemistry-
dc.subject.meshDurapatite - metabolism-
dc.subject.meshSilicates - chemical synthesis - chemistry-
dc.subject.meshStrontium - chemistry-
dc.titleSynthesis, in vitro hydroxyapatite forming ability, and cytocompatibility of strontium silicate powdersen_US
dc.typeArticleen_US
dc.identifier.emailPan, H: haobo@hku.hken_US
dc.identifier.emailLu, WW: wwlu@hkusua.hku.hken_US
dc.identifier.authorityPan, H=rp01564en_US
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/jbm.b.31582-
dc.identifier.pmid20091923-
dc.identifier.scopuseid_2-s2.0-77949527777-
dc.identifier.hkuros176714en_US
dc.identifier.volume93en_US
dc.identifier.issue1en_US
dc.identifier.spage252en_US
dc.identifier.epage257en_US
dc.identifier.isiWOS:000275796700028-
dc.publisher.placeUnited States-

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