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Article: Electroacupuncture for refractory obsessive-compulsive disorder: A pilot waitlist-controlled trial

TitleElectroacupuncture for refractory obsessive-compulsive disorder: A pilot waitlist-controlled trial
Authors
KeywordsElectroacupuncture
Obsessive-compulsive disorder
Pilot trial
Issue Date2009
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.jonmd.com
Citation
Journal Of Nervous And Mental Disease, 2009, v. 197 n. 8, p. 619-622 How to Cite?
AbstractA large proportion of obsessive-compulsive disorder (OCD) patients are refractory to pharmacological and cognitive-behavioral therapy. The aim of this pilot, waitlist-controlled trial was to evaluate the effectiveness of electroacupuncture (EA) as add-on therapy for treatment-resistant OCD. Nineteen patients with treatment-resistant OCD were assigned to EA treatment for 12 sessions (5 sessions per week, n = 10) or waitlist for controls (n = 9) while continuing their current anti-OCD medications. The clinical outcomes were measured using the Yale-Brown Obsessive-Compulsive Scale and the Clinical Global Impression-Severity at baseline and end point. EA additional treatment produced significantly greater improvements at end point compared with the waitlist group in reducing both Yale-Brown Obsessive-Compulsive Scale (10.2 ± 4.2 vs. 18.8 ± 7.4, p = 0.004) and Clinical Global Impression-Severity scores (3.0 ± 1.1 vs. 4.4 ± 1.1, p = 0.002). As an additional therapy, EA is effective in alleviating OCD symptoms of treatment-resistant patients. A large-scale controlled study is warranted. © 2009 Lippincott Williams & Wilkins, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/127613
ISSN
2015 Impact Factor: 1.836
2015 SCImago Journal Rankings: 0.929
ISI Accession Number ID
Funding AgencyGrant Number
Sir Michael and Lady Kadoorie charitable donation: Natural Science Foundation of China30870886
11th Five-Year Project of Military Medicine Foundations2008ZXJ09014-002
08Z031
Funding Information:

Supported by projects funded by Sir Michael and Lady Kadoorie charitable donation: Natural Science Foundation of China (No. 30870886) and the 11th Five-Year Project of Military Medicine Foundations (2008ZXJ09014-002 and 08Z031).

References

 

DC FieldValueLanguage
dc.contributor.authorZhang, ZJen_HK
dc.contributor.authorWang, XYen_HK
dc.contributor.authorTan, QRen_HK
dc.contributor.authorJin, GXen_HK
dc.contributor.authorYao, SMen_HK
dc.date.accessioned2010-10-31T13:35:40Z-
dc.date.available2010-10-31T13:35:40Z-
dc.date.issued2009en_HK
dc.identifier.citationJournal Of Nervous And Mental Disease, 2009, v. 197 n. 8, p. 619-622en_HK
dc.identifier.issn0022-3018en_HK
dc.identifier.urihttp://hdl.handle.net/10722/127613-
dc.description.abstractA large proportion of obsessive-compulsive disorder (OCD) patients are refractory to pharmacological and cognitive-behavioral therapy. The aim of this pilot, waitlist-controlled trial was to evaluate the effectiveness of electroacupuncture (EA) as add-on therapy for treatment-resistant OCD. Nineteen patients with treatment-resistant OCD were assigned to EA treatment for 12 sessions (5 sessions per week, n = 10) or waitlist for controls (n = 9) while continuing their current anti-OCD medications. The clinical outcomes were measured using the Yale-Brown Obsessive-Compulsive Scale and the Clinical Global Impression-Severity at baseline and end point. EA additional treatment produced significantly greater improvements at end point compared with the waitlist group in reducing both Yale-Brown Obsessive-Compulsive Scale (10.2 ± 4.2 vs. 18.8 ± 7.4, p = 0.004) and Clinical Global Impression-Severity scores (3.0 ± 1.1 vs. 4.4 ± 1.1, p = 0.002). As an additional therapy, EA is effective in alleviating OCD symptoms of treatment-resistant patients. A large-scale controlled study is warranted. © 2009 Lippincott Williams & Wilkins, Inc.en_HK
dc.languageengen_HK
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.jonmd.comen_HK
dc.relation.ispartofJournal of Nervous and Mental Diseaseen_HK
dc.subjectElectroacupunctureen_HK
dc.subjectObsessive-compulsive disorderen_HK
dc.subjectPilot trialen_HK
dc.subject.meshCombined Modality Therapy-
dc.subject.meshEndpoint Determination-
dc.subject.meshSeverity of Illness Index-
dc.subject.meshElectroacupuncture - methods-
dc.subject.meshObsessive-Compulsive Disorder - diagnosis - drug therapy - therapy-
dc.titleElectroacupuncture for refractory obsessive-compulsive disorder: A pilot waitlist-controlled trialen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0022-3018&volume=197&issue=8&spage=619&epage=622&date=2009&atitle=Electroacupuncture+for+refractory+obsessive-compulsive+disorder:+a+pilot,+waitlist-controlled+trialen_HK
dc.identifier.emailZhang, ZJ: zhangzj@hkucc.hku.hken_HK
dc.identifier.authorityZhang, ZJ=rp01297en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1097/NMD.0b013e3181b05fd1en_HK
dc.identifier.pmid19684500en_HK
dc.identifier.scopuseid_2-s2.0-68949090453en_HK
dc.identifier.hkuros174203en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-68949090453&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume197en_HK
dc.identifier.issue8en_HK
dc.identifier.spage619en_HK
dc.identifier.epage622en_HK
dc.identifier.isiWOS:000269164300011-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridZhang, ZJ=8061473900en_HK
dc.identifier.scopusauthoridWang, XY=7501875577en_HK
dc.identifier.scopusauthoridTan, QR=7102120177en_HK
dc.identifier.scopusauthoridJin, GX=16203020200en_HK
dc.identifier.scopusauthoridYao, SM=15053852100en_HK

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