File Download
  Links for fulltext
     (May Require Subscription)

Conference Paper: MicroRNA-135a regulates early embryo development through mediating expression of E3 ubiquitin ligase seven in absentia Homolog 1 (SIAH1)

TitleMicroRNA-135a regulates early embryo development through mediating expression of E3 ubiquitin ligase seven in absentia Homolog 1 (SIAH1)
Authors
KeywordsMedical sciences
Obstetrics and gynecology medical sciences
Endocrinology pharmacy and pharmacology
Issue Date2010
PublisherOxford University Press. The Journal's web site is located at http://humrep.oxfordjournals.org/
Citation
The 26th Annual Meeting of European Society for Human Reproduction and Embryology (ESHRE 2010), Rome, Italy, 27-30 June 2010. In Human Reproduction, 2010, v. 25 suppl. 1, p. i191, abstract P-193 How to Cite?
AbstractINTRODUCTION: MicroRNAs (miRNAs) are single-stranded 19-25 nucleotide non-coding RNA molecules capable of regulating gene expression at both transcription and translation levels (Denli et al., 2004). There are more than 700 known human miRNAs. It is estimated that they regulate more than 30% of all protein coding genes (Berezikov et al., 2005). MiRNAs are involved in many physiological process and diseases. Knockout mice lacking miRNA processing machinery Dicer died at embryonic day 7.5 (Bernstein et al., 2003). To investigate whether miRNA played a role in early embryo development, we had determined the miRNA profile of mouse preimplantation embryos. We found that miR-135a was specifically expressed in the zygotes and decreased upon development, consistent with the involvement of the miRNA in early embryo development. This study aimed at evaluating the role of miR-135a in embryo development through in silico and in vitro approaches …
DescriptionPoster Session - Embryology (Embryo Selection): P-193
Basic Science Award
This FREE journal suppl. entitled: Abstracts of the 26th Annual Meeting of the European Society of Human Reproduction and Embryology, Rome, Italy, 27-30 June 2010
Persistent Identifierhttp://hdl.handle.net/10722/127518
ISSN
2015 Impact Factor: 4.621
2015 SCImago Journal Rankings: 2.271

 

DC FieldValueLanguage
dc.contributor.authorLeung, CON-
dc.contributor.authorPang, RTK-
dc.contributor.authorLiu, W-
dc.contributor.authorLee, KF-
dc.contributor.authorYeung, WSB-
dc.date.accessioned2010-10-31T13:30:10Z-
dc.date.available2010-10-31T13:30:10Z-
dc.date.issued2010-
dc.identifier.citationThe 26th Annual Meeting of European Society for Human Reproduction and Embryology (ESHRE 2010), Rome, Italy, 27-30 June 2010. In Human Reproduction, 2010, v. 25 suppl. 1, p. i191, abstract P-193-
dc.identifier.issn0268-1161-
dc.identifier.urihttp://hdl.handle.net/10722/127518-
dc.descriptionPoster Session - Embryology (Embryo Selection): P-193-
dc.descriptionBasic Science Award-
dc.descriptionThis FREE journal suppl. entitled: Abstracts of the 26th Annual Meeting of the European Society of Human Reproduction and Embryology, Rome, Italy, 27-30 June 2010-
dc.description.abstractINTRODUCTION: MicroRNAs (miRNAs) are single-stranded 19-25 nucleotide non-coding RNA molecules capable of regulating gene expression at both transcription and translation levels (Denli et al., 2004). There are more than 700 known human miRNAs. It is estimated that they regulate more than 30% of all protein coding genes (Berezikov et al., 2005). MiRNAs are involved in many physiological process and diseases. Knockout mice lacking miRNA processing machinery Dicer died at embryonic day 7.5 (Bernstein et al., 2003). To investigate whether miRNA played a role in early embryo development, we had determined the miRNA profile of mouse preimplantation embryos. We found that miR-135a was specifically expressed in the zygotes and decreased upon development, consistent with the involvement of the miRNA in early embryo development. This study aimed at evaluating the role of miR-135a in embryo development through in silico and in vitro approaches …-
dc.languageeng-
dc.publisherOxford University Press. The Journal's web site is located at http://humrep.oxfordjournals.org/-
dc.relation.ispartofHuman Reproduction-
dc.subjectMedical sciences-
dc.subjectObstetrics and gynecology medical sciences-
dc.subjectEndocrinology pharmacy and pharmacology-
dc.titleMicroRNA-135a regulates early embryo development through mediating expression of E3 ubiquitin ligase seven in absentia Homolog 1 (SIAH1)-
dc.typeConference_Paper-
dc.identifier.emailLeung, CON: carmenon@hku.hk-
dc.identifier.emailPang, RTK: rtkpang@hku.hk-
dc.identifier.emailLiu, W: liuwm@hkucc.hku.hk-
dc.identifier.emailLee, KF: ckflee@hku.hk-
dc.identifier.emailYeung, WSB: wsbyeung@hkucc.hku.hk-
dc.identifier.authorityPang, RTK=rp01761-
dc.identifier.authorityLee, KF=rp00458-
dc.identifier.authorityYeung, WSB=rp00331-
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1093/humrep/de.25.s1.140-
dc.identifier.hkuros179177-
dc.identifier.hkuros231974-
dc.identifier.volume25-
dc.identifier.issuesuppl. 1-
dc.identifier.spagei191, abstract P-193-
dc.identifier.epagei191, abstract P-193-
dc.publisher.placeUnited Kingdom-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats