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Conference Paper: Living donor liver transplantation for hepatocellular carcinoma across Milan criteria

TitleLiving donor liver transplantation for hepatocellular carcinoma across Milan criteria
Authors
Issue Date2009
PublisherSpringer New York LLC. The Journal's web site is located at http://link.springer.de/link/service/journals/00268/
Citation
The International Surgical Week (ISW 2009), Adelaide, Australia, 6-10 September 2009. In World Journal of Surgery, 2009, v. 33 suppl. 1, p. S107, abstract no. 0276 How to Cite?
AbstractINTRODUCTION: Liver transplantation is the best treatment option for patients with unresectable hepatocellular carcinoma (HCC) and liver cirrhosis. Although restrictive selection criteria using Milan criteria yielded excellent survival results, the outcome of LDLT under extended selection criteria for HCC remains controversial. AIM OF STUDY: To investigate the outcome of LDLT for HCC using extended selection criteria for HCC. MATERIAL AND METHODS: A total of 83 patients who underwent LDLT for HCC were retrospectively analyzed. Patients with extrahepatic metastases, major vascular tumor invasion and diffuse HCC were excluded. Recurrence-free survival results were analyzed. Significant prognostic factors were identified using univariate and multivariate analyses. RESULTS: Thirty-three patients (39.8%) had HCC with pathological features exceeding Milan criteria. The median follow-up period was 46 months (22–120 months). The short-term outcomes between two groups were comparable. The 1-year, 3-year and 5-year recurrence-free survival rates for patients within Milan criteria were 93%, 78% and 72%, whereas those for patients beyond Milan criteria were 90%, 70% and 60%. There was no statistically significant difference between two groups. Treatment before liver transplantation was the independent poor prognostic factor for recurrence-free survival.
DescriptionThis journal suppl. is proceedings of International Surgical Week ISW 2009
Free Paper (Oral) - Session: 106.05: abstract ID: 0276
Persistent Identifierhttp://hdl.handle.net/10722/126988
ISSN
2015 Impact Factor: 2.523
2015 SCImago Journal Rankings: 1.375

 

DC FieldValueLanguage
dc.contributor.authorNg, KKCen_HK
dc.contributor.authorLo, CMen_HK
dc.contributor.authorChan, SCen_HK
dc.contributor.authorFan, STen_HK
dc.date.accessioned2010-10-31T12:59:55Z-
dc.date.available2010-10-31T12:59:55Z-
dc.date.issued2009en_HK
dc.identifier.citationThe International Surgical Week (ISW 2009), Adelaide, Australia, 6-10 September 2009. In World Journal of Surgery, 2009, v. 33 suppl. 1, p. S107, abstract no. 0276en_HK
dc.identifier.issn0364-2313-
dc.identifier.urihttp://hdl.handle.net/10722/126988-
dc.descriptionThis journal suppl. is proceedings of International Surgical Week ISW 2009-
dc.descriptionFree Paper (Oral) - Session: 106.05: abstract ID: 0276-
dc.description.abstractINTRODUCTION: Liver transplantation is the best treatment option for patients with unresectable hepatocellular carcinoma (HCC) and liver cirrhosis. Although restrictive selection criteria using Milan criteria yielded excellent survival results, the outcome of LDLT under extended selection criteria for HCC remains controversial. AIM OF STUDY: To investigate the outcome of LDLT for HCC using extended selection criteria for HCC. MATERIAL AND METHODS: A total of 83 patients who underwent LDLT for HCC were retrospectively analyzed. Patients with extrahepatic metastases, major vascular tumor invasion and diffuse HCC were excluded. Recurrence-free survival results were analyzed. Significant prognostic factors were identified using univariate and multivariate analyses. RESULTS: Thirty-three patients (39.8%) had HCC with pathological features exceeding Milan criteria. The median follow-up period was 46 months (22–120 months). The short-term outcomes between two groups were comparable. The 1-year, 3-year and 5-year recurrence-free survival rates for patients within Milan criteria were 93%, 78% and 72%, whereas those for patients beyond Milan criteria were 90%, 70% and 60%. There was no statistically significant difference between two groups. Treatment before liver transplantation was the independent poor prognostic factor for recurrence-free survival.-
dc.languageengen_HK
dc.publisherSpringer New York LLC. The Journal's web site is located at http://link.springer.de/link/service/journals/00268/-
dc.relation.ispartofWorld Journal of Surgery-
dc.rightsThe original publication is available at www.springerlink.com-
dc.subject.meshGeneral Surgery-
dc.subject.meshHumans-
dc.subject.meshSurgical Procedures, Operative-
dc.titleLiving donor liver transplantation for hepatocellular carcinoma across Milan criteriaen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailNg, KKC: kkcng@hkucc.hku.hken_HK
dc.identifier.emailLo, CM: chungmlo@hkucc.hku.hken_HK
dc.identifier.emailChan, SC: chanlsc@hkucc.hku.hken_HK
dc.identifier.emailFan, ST: stfan@hku.hken_HK
dc.identifier.authorityLo, CM=rp00412en_HK
dc.identifier.authorityChan, SC=rp01568en_HK
dc.identifier.doi10.1007/s00268-009-0165-5-
dc.identifier.pmid19655197-
dc.identifier.hkuros180771en_HK
dc.identifier.volume33-
dc.identifier.issuesuppl. 1-
dc.identifier.spageS107-
dc.identifier.epageS107-
dc.publisher.placeUnited States-
dc.customcontrol.immutablesml 130610-

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