Conference Paper: Posterior Reversible Encephalopathy Syndrome: paediatric heart transplant with cyclosporine neurotoxicity

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Title	Posterior Reversible Encephalopathy Syndrome: paediatric heart transplant with cyclosporine neurotoxicity
Authors	Tso, WWY Yung, AWY Lun, KS Yung, TC Fan, K Wong, VCN
Keywords	Medical sciences
Issue Date	2009
Publisher	Hong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org.hk
Citation	The 1st Hong Kong Neurological Congress cum 22nd Annual Scientific Meeting of the Hong Kong Neurological Society, Hong Kong, 6-8 November 2009. In Hong Kong Medical Journal, 2009, v. 15 n. 6, suppl. 7, p. 42, abstract P8 [How to Cite?]
Abstract	Posterior reversible encephalopathy syndrome (PRES) is associated with a specific disorder of cerebrovascular autoregulation. Clinical features of PRES consisted of headache, decreased consciousness, altered mental functioning, seizures, visual loss or cortical blindness. Characteristic findings on neuroimaging included high signal intensity on T2-weighted as well as diffusion-weighted imaging MRI in the posterior cerebral hemispheres, indicative of vasogenic subcortical oedema without infarction. Cyclosporine neurotoxicity had been described following bone marrow and organ transplantation; however, there are few reports of PRES in children especially post-paediatric heart transplantation. We report a case of cyclosporine-related PRES in a paediatric heart transplant recipient. She made a good recovery with no residual neurological deficits after withdrawal of cyclosporine, control of possible risk factors as well as symptomatic control of seizure.
Description	Posters: P8
ISSN	1024-2708 2011 SCImago Journal Rankings: 0.054

DC Field	Value
dc.contributor.author	Tso, WWY
dc.contributor.author	Yung, AWY
dc.contributor.author	Lun, KS
dc.contributor.author	Yung, TC
dc.contributor.author	Fan, K
dc.contributor.author	Wong, VCN
dc.date.accessioned	2010-10-31T12:51:07Z
dc.date.available	2010-10-31T12:51:07Z
dc.date.issued	2009
dc.description.abstract	Posterior reversible encephalopathy syndrome (PRES) is associated with a specific disorder of cerebrovascular autoregulation. Clinical features of PRES consisted of headache, decreased consciousness, altered mental functioning, seizures, visual loss or cortical blindness. Characteristic findings on neuroimaging included high signal intensity on T2-weighted as well as diffusion-weighted imaging MRI in the posterior cerebral hemispheres, indicative of vasogenic subcortical oedema without infarction. Cyclosporine neurotoxicity had been described following bone marrow and organ transplantation; however, there are few reports of PRES in children especially post-paediatric heart transplantation. We report a case of cyclosporine-related PRES in a paediatric heart transplant recipient. She made a good recovery with no residual neurological deficits after withdrawal of cyclosporine, control of possible risk factors as well as symptomatic control of seizure.
dc.description.nature	published_or_final_version
dc.description	Posters: P8
dc.description.other	The 1st Hong Kong Neurological Congress cum 22nd Annual Scientific Meeting of the Hong Kong Neurological Society, Hong Kong, 6-8 November 2009. In Hong Kong Medical Journal, 2009, v. 15 n. 6, suppl. 7, p. 42, abstract P8
dc.identifier.citation	The 1st Hong Kong Neurological Congress cum 22nd Annual Scientific Meeting of the Hong Kong Neurological Society, Hong Kong, 6-8 November 2009. In Hong Kong Medical Journal, 2009, v. 15 n. 6, suppl. 7, p. 42, abstract P8 [How to Cite?]
dc.identifier.epage	42
dc.identifier.hkuros	168167
dc.identifier.issn	1024-2708 2011 SCImago Journal Rankings: 0.054
dc.identifier.issue	6, suppl. 7
dc.identifier.spage	42
dc.identifier.uri	http://hdl.handle.net/10722/126830
dc.identifier.volume	15
dc.language	eng
dc.publisher	Hong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org.hk
dc.publisher.place	Hong Kong
dc.relation.ispartof	Hong Kong Medical Journal
dc.rights	Hong Kong Medical Journal. Copyright © Hong Kong Academy of Medicine Press.
dc.rights	Creative Commons: Attribution 3.0 Hong Kong License
dc.subject	Medical sciences
dc.title	Posterior Reversible Encephalopathy Syndrome: paediatric heart transplant with cyclosporine neurotoxicity
dc.type	Conference_Paper

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