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Article: Mature miR-184 and squamous cell carcinoma of the tongue

TitleMature miR-184 and squamous cell carcinoma of the tongue
Authors
Wong, TSHo, WKChan, JYWNg, RWMWei, WI
KeywordsMicroRNA
Post-transcriptional regulators
Squamous cell carcinoma
Tongue cancer
Issue Date2009
PublisherThe ScientificWorld Ltd. The Journal's web site is located at http://www.hindawi.com/journals/tswj/
Citation
TheScientificWorldJournal, 2009, v. 9, p. 130-132 How to Cite?
DOI: http://dx.doi.org/10.1100/tsw.2009.12
AbstractHuman microRNA 184 (miR-184) is overexpressed in squamous cell carcinoma (SCC) of the tongue. In vitro inhibition of miR-184 levels could induce apoptosis and hinder proliferation of tongue SCC cells. Patients with tongue SCC have high plasma miR-184 levels. Plasma miR-184 is likely associated with the tumor load. Surgical removal of the primary tumor reduced plasma miR-184 levels significantly. The data suggested that miR-184 is linked to the pathogenesis of tongue SCC. Further studies are warranted to evaluate the use of microRNA-based serological markers in monitoring tongue SCC.
Persistent Identifierhttp://hdl.handle.net/10722/125445
ISSN
1537-744X
2013 Impact Factor: 1.219
2020 SCImago Journal Rankings: 0.453
ISI Accession Number ID
WOS:000263381800006
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorWong, TSen_HK
dc.contributor.authorHo, WKen_HK
dc.contributor.authorChan, JYWen_HK
dc.contributor.authorNg, RWMen_HK
dc.contributor.authorWei, WIen_HK
dc.date.accessioned2010-10-31T11:31:49Z-
dc.date.available2010-10-31T11:31:49Z-
dc.date.issued2009en_HK
dc.identifier.citationTheScientificWorldJournal, 2009, v. 9, p. 130-132en_HK
dc.identifier.issn1537-744Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/125445-
dc.description.abstractHuman microRNA 184 (miR-184) is overexpressed in squamous cell carcinoma (SCC) of the tongue. In vitro inhibition of miR-184 levels could induce apoptosis and hinder proliferation of tongue SCC cells. Patients with tongue SCC have high plasma miR-184 levels. Plasma miR-184 is likely associated with the tumor load. Surgical removal of the primary tumor reduced plasma miR-184 levels significantly. The data suggested that miR-184 is linked to the pathogenesis of tongue SCC. Further studies are warranted to evaluate the use of microRNA-based serological markers in monitoring tongue SCC.-
dc.languageengen_HK
dc.publisherThe ScientificWorld Ltd. The Journal's web site is located at http://www.hindawi.com/journals/tswj/en_HK
dc.relation.ispartofTheScientificWorldJournalen_HK
dc.subjectMicroRNAen_HK
dc.subjectPost-transcriptional regulatorsen_HK
dc.subjectSquamous cell carcinomaen_HK
dc.subjectTongue canceren_HK
dc.subject.meshCarcinoma, Squamous Cell - genetics-
dc.subject.meshGene Expression Regulation, Neoplastic-
dc.subject.meshHumans-
dc.subject.meshMicroRNAs - genetics - metabolism-
dc.subject.meshTongue Neoplasms - genetics-
dc.titleMature miR-184 and squamous cell carcinoma of the tongueen_HK
dc.typeArticleen_HK
dc.identifier.emailWong, TS: thiansze@graduate.hku.hken_HK
dc.identifier.emailChan, JYW: jywchan1@hku.hken_HK
dc.identifier.emailWei, WI: hrmswwi@hku.hken_HK
dc.identifier.authorityWong, TS=rp00478en_HK
dc.identifier.authorityChan, JYW=rp01314en_HK
dc.identifier.authorityWei, WI=rp00323en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1100/tsw.2009.12en_HK
dc.identifier.pmid19219377-
dc.identifier.scopuseid_2-s2.0-63649123792en_HK
dc.identifier.hkuros182405en_HK
dc.identifier.hkuros176171-
dc.identifier.hkuros154666-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-63649123792&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume9en_HK
dc.identifier.spage130en_HK
dc.identifier.epage132en_HK
dc.identifier.isiWOS:000263381800006-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridWong, TS=7403531328en_HK
dc.identifier.scopusauthoridHo, WK=7402968844en_HK
dc.identifier.scopusauthoridChan, JYW=27171772200en_HK
dc.identifier.scopusauthoridNg, RWM=7102153861en_HK
dc.identifier.scopusauthoridWei, WI=7403321552en_HK
dc.identifier.citeulike4066613-
dc.identifier.issnl1537-744X-

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