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Article: International reproducibility of single breathhold T2* MR for cardiac and liver iron assessment among five thalassemia centers

TitleInternational reproducibility of single breathhold T2* MR for cardiac and liver iron assessment among five thalassemia centers
Authors
KeywordsCardiac siderosis
Cardiomyopathy
Cardiovascular MR
Thalassemia
Issue Date2010
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/1053-1807/
Citation
Journal Of Magnetic Resonance Imaging, 2010, v. 32 n. 2, p. 315-319 How to Cite?
Abstract
Purpose: To examine the reproducibility of the single breathhold T2* technique fromdifferent scanners, after installation of standardmethodology in five international centers. Materials and Methods: Up to 10 patients from each center were scanned twice locally for local interstudy reproducibility of heart and liver T2*, and then flown to a central MR facility to be rescanned on a reference scanner for intercenter reproducibility. Interobserver reproducibility for all scans was also assessed. Results: Of the 49 patients scanned, the intercenter reproducibility for T2* was 5.9% for the heart and 5.8% for the liver. Local interstudy reproducibility for T2* was 7.4% for the heart and 4.6% for the liver. Interobserver reproducibility for T2* was 5.4% for the heart and 4.4% for the liver. Conclusion: These data indicate that T2* MR may be developed into a widespread test for tissue siderosis providing that well-defined and approved imaging and analysis techniques are used. © 2010 Wiley-Liss, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/125231
ISSN
2013 Impact Factor: 2.788
PubMed Central ID
ISI Accession Number ID
Funding AgencyGrant Number
National Institutes of Health5 R01 DK066084-02
National Institutes of Health Research Biomedical Research Unit of Royal Brompton Hospital
Imperial College
Funding Information:

Contract grant sponsor: National Institutes of Health; Contract grant number: 5 R01 DK066084-02

References

 

Author Affiliations
  1. Singapore General Hospital
  2. Royal Brompton Hospital
  3. KK Women's And Children's Hospital
  4. The Children's Hospital of Philadelphia
  5. The University of Hong Kong
  6. National Heart Centre, Singapore
  7. Azienda Ospedaliera Brotzu
  8. Ospedale Regionale Microcitemie
  9. Mahidol University
  10. Chinese University of Hong Kong
DC FieldValueLanguage
dc.contributor.authorKirk, Pen_HK
dc.contributor.authorHe, Ten_HK
dc.contributor.authorAnderson, LJen_HK
dc.contributor.authorRoughton, Men_HK
dc.contributor.authorTanner, MAen_HK
dc.contributor.authorLam, WWMen_HK
dc.contributor.authorAu, WYen_HK
dc.contributor.authorChu, WCWen_HK
dc.contributor.authorChan, Gen_HK
dc.contributor.authorGalanello, Ren_HK
dc.contributor.authorMatta, Gen_HK
dc.contributor.authorFogel, Men_HK
dc.contributor.authorCohen, ARen_HK
dc.contributor.authorTan, RSen_HK
dc.contributor.authorChen, Ken_HK
dc.contributor.authorNg, Ien_HK
dc.contributor.authorLai, Aen_HK
dc.contributor.authorFucharoen, Sen_HK
dc.contributor.authorLaothamata, Jen_HK
dc.contributor.authorChuncharunee, Sen_HK
dc.contributor.authorJongjirasiri, Sen_HK
dc.contributor.authorFirmin, DNen_HK
dc.contributor.authorSmith, GCen_HK
dc.contributor.authorPennell, DJen_HK
dc.date.accessioned2010-10-31T11:18:54Z-
dc.date.available2010-10-31T11:18:54Z-
dc.date.issued2010en_HK
dc.identifier.citationJournal Of Magnetic Resonance Imaging, 2010, v. 32 n. 2, p. 315-319en_HK
dc.identifier.issn1053-1807en_HK
dc.identifier.urihttp://hdl.handle.net/10722/125231-
dc.description.abstractPurpose: To examine the reproducibility of the single breathhold T2* technique fromdifferent scanners, after installation of standardmethodology in five international centers. Materials and Methods: Up to 10 patients from each center were scanned twice locally for local interstudy reproducibility of heart and liver T2*, and then flown to a central MR facility to be rescanned on a reference scanner for intercenter reproducibility. Interobserver reproducibility for all scans was also assessed. Results: Of the 49 patients scanned, the intercenter reproducibility for T2* was 5.9% for the heart and 5.8% for the liver. Local interstudy reproducibility for T2* was 7.4% for the heart and 4.6% for the liver. Interobserver reproducibility for T2* was 5.4% for the heart and 4.4% for the liver. Conclusion: These data indicate that T2* MR may be developed into a widespread test for tissue siderosis providing that well-defined and approved imaging and analysis techniques are used. © 2010 Wiley-Liss, Inc.en_HK
dc.languageengen_HK
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/1053-1807/en_HK
dc.relation.ispartofJournal of Magnetic Resonance Imagingen_HK
dc.rightsJournal of Magnetic Resonance Imaging. Copyright © John Wiley & Sons, Inc.-
dc.subjectCardiac siderosisen_HK
dc.subjectCardiomyopathyen_HK
dc.subjectCardiovascular MRen_HK
dc.subjectThalassemiaen_HK
dc.titleInternational reproducibility of single breathhold T2* MR for cardiac and liver iron assessment among five thalassemia centersen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1053-1807&volume=32&issue=2&spage=315&epage=319&date=2010&atitle=International+reproducibility+of+single+breathhold+T2*+MR+for+cardic+and+liver+iron+assessment+among+five+thalassemia+centers-
dc.identifier.emailChan, G:gcfchan@hkucc.hku.hken_HK
dc.identifier.authorityChan, G=rp00431en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/jmri.22245en_HK
dc.identifier.pmid20677256en_HK
dc.identifier.pmcidPMC2946327-
dc.identifier.scopuseid_2-s2.0-77955365667en_HK
dc.identifier.hkuros179097en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77955365667&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume32en_HK
dc.identifier.issue2en_HK
dc.identifier.spage315en_HK
dc.identifier.epage319en_HK
dc.identifier.isiWOS:000280447300008-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridKirk, P=24474747700en_HK
dc.identifier.scopusauthoridHe, T=34570131700en_HK
dc.identifier.scopusauthoridAnderson, LJ=7403741602en_HK
dc.identifier.scopusauthoridRoughton, M=24067576200en_HK
dc.identifier.scopusauthoridTanner, MA=13907612900en_HK
dc.identifier.scopusauthoridLam, WWM=13410486800en_HK
dc.identifier.scopusauthoridAu, WY=7202383089en_HK
dc.identifier.scopusauthoridChu, WCW=7402227871en_HK
dc.identifier.scopusauthoridChan, G=16160154400en_HK
dc.identifier.scopusauthoridGalanello, R=7004292185en_HK
dc.identifier.scopusauthoridMatta, G=6506763913en_HK
dc.identifier.scopusauthoridFogel, M=7102455134en_HK
dc.identifier.scopusauthoridCohen, AR=7404780851en_HK
dc.identifier.scopusauthoridTan, RS=7201984906en_HK
dc.identifier.scopusauthoridChen, K=36458173600en_HK
dc.identifier.scopusauthoridNg, I=46461891700en_HK
dc.identifier.scopusauthoridLai, A=36458559200en_HK
dc.identifier.scopusauthoridFucharoen, S=7103089590en_HK
dc.identifier.scopusauthoridLaothamata, J=36242024200en_HK
dc.identifier.scopusauthoridChuncharunee, S=6701490020en_HK
dc.identifier.scopusauthoridJongjirasiri, S=8562774500en_HK
dc.identifier.scopusauthoridFirmin, DN=7007100394en_HK
dc.identifier.scopusauthoridSmith, GC=35467183800en_HK
dc.identifier.scopusauthoridPennell, DJ=7103221771en_HK

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