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Article: Predictors of inhospital outcome after acute inferior wall myocardial infarction

TitlePredictors of inhospital outcome after acute inferior wall myocardial infarction
Authors
Issue Date2009
PublisherSingapore Medical Association. The Journal's web site is located at http://www.sma.org.sg/smj/smjcurrent.html
Citation
Singapore Medical Journal, 2009, v. 50 n. 10, p. 956-961 How to Cite?
AbstractIntroduction: Compared with anterior wall myocardial infarction, inferior wall myocardial infarction is generally regarded as being low risk. The aim of this study was to elucidate the clinical factors affecting its inhospital outcome. Methods: From January 1997 to March 2006, 546 consecutive patients who suffered from their first inferior wall myocardial infarction were recruited for the study. The demographic, clinical, electrocardiographical and angiographical characteristics, treatment and medications, complications and inhospital deaths were subjected to univariate analysis. The factors that had a p-value of less than 0.1 were included for multivariate logistic regression analysis. A p-value of less than 0.05 was considered significant. The impact of thrombolysis on clinical outcome in various high-risk patient subsets was also examined. Results: An advanced age of more than 74 years, female gender, lateral wall extension, complete atrioventricular block, bundle branch block, and cardiac free-wall rupture were found to be independent predictors of inhospital mortality, whereas the use of thrombolysis was associated with a favourable outcome. On the other hand, right ventricular infarction and precordial ST-segment depression are not predictive of poor outcome. In addition, thrombolysis reduced inhospital mortality in patients with an age above 64 years, male gender, lateral wall extension, haemodynamically-significant right ventricular infarction and complete atrioventricular block. Conclusion: In inferior wall myocardial infarction, independent predictors of poor inhospital outcome are advanced age, female gender, lateral wall extension, complete atrioventricular block, bundle branch block and cardiac free-wall rupture. The use of thrombolysis is generally beneficial, especially in those of the high-risk subsets.
Persistent Identifierhttp://hdl.handle.net/10722/124971
ISSN
2015 Impact Factor: 0.573
2015 SCImago Journal Rankings: 0.311
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorJim, MHen_HK
dc.contributor.authorChan, AOen_HK
dc.contributor.authorTse, HFen_HK
dc.contributor.authorLau, CPen_HK
dc.date.accessioned2010-10-31T11:04:20Z-
dc.date.available2010-10-31T11:04:20Z-
dc.date.issued2009en_HK
dc.identifier.citationSingapore Medical Journal, 2009, v. 50 n. 10, p. 956-961en_HK
dc.identifier.issn0037-5675en_HK
dc.identifier.urihttp://hdl.handle.net/10722/124971-
dc.description.abstractIntroduction: Compared with anterior wall myocardial infarction, inferior wall myocardial infarction is generally regarded as being low risk. The aim of this study was to elucidate the clinical factors affecting its inhospital outcome. Methods: From January 1997 to March 2006, 546 consecutive patients who suffered from their first inferior wall myocardial infarction were recruited for the study. The demographic, clinical, electrocardiographical and angiographical characteristics, treatment and medications, complications and inhospital deaths were subjected to univariate analysis. The factors that had a p-value of less than 0.1 were included for multivariate logistic regression analysis. A p-value of less than 0.05 was considered significant. The impact of thrombolysis on clinical outcome in various high-risk patient subsets was also examined. Results: An advanced age of more than 74 years, female gender, lateral wall extension, complete atrioventricular block, bundle branch block, and cardiac free-wall rupture were found to be independent predictors of inhospital mortality, whereas the use of thrombolysis was associated with a favourable outcome. On the other hand, right ventricular infarction and precordial ST-segment depression are not predictive of poor outcome. In addition, thrombolysis reduced inhospital mortality in patients with an age above 64 years, male gender, lateral wall extension, haemodynamically-significant right ventricular infarction and complete atrioventricular block. Conclusion: In inferior wall myocardial infarction, independent predictors of poor inhospital outcome are advanced age, female gender, lateral wall extension, complete atrioventricular block, bundle branch block and cardiac free-wall rupture. The use of thrombolysis is generally beneficial, especially in those of the high-risk subsets.en_HK
dc.languageengen_HK
dc.publisherSingapore Medical Association. The Journal's web site is located at http://www.sma.org.sg/smj/smjcurrent.htmlen_HK
dc.relation.ispartofSingapore Medical Journalen_HK
dc.subject.meshAgeden_HK
dc.subject.meshAngiography - methodsen_HK
dc.subject.meshCardiology - methodsen_HK
dc.subject.meshElectrocardiography - methodsen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHeart Ventricles - physiopathologyen_HK
dc.subject.meshHospitalsen_HK
dc.subject.meshHumansen_HK
dc.subject.meshInferior Wall Myocardial Infarction - diagnosis - therapyen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshMultivariate Analysisen_HK
dc.subject.meshRisk Factorsen_HK
dc.subject.meshThrombolytic Therapy - methodsen_HK
dc.subject.meshTreatment Outcomeen_HK
dc.titlePredictors of inhospital outcome after acute inferior wall myocardial infarctionen_HK
dc.typeArticleen_HK
dc.identifier.emailTse, HF:hftse@hkucc.hku.hken_HK
dc.identifier.authorityTse, HF=rp00428en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.pmid19907884-
dc.identifier.scopuseid_2-s2.0-74549135829en_HK
dc.identifier.hkuros173622en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-74549135829&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume50en_HK
dc.identifier.issue10en_HK
dc.identifier.spage956en_HK
dc.identifier.epage961en_HK
dc.identifier.isiWOS:000271745800006-
dc.publisher.placeSingaporeen_HK
dc.identifier.scopusauthoridJim, MH=6603860344en_HK
dc.identifier.scopusauthoridChan, AO=7403167965en_HK
dc.identifier.scopusauthoridTse, HF=7006070805en_HK
dc.identifier.scopusauthoridLau, CP=7401968501en_HK

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