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Article: Effects of processing parameters on the morphology and size of electrospun PHBV micro- And nano-fibers

TitleEffects of processing parameters on the morphology and size of electrospun PHBV micro- And nano-fibers
Authors
KeywordsElectrospinning
Microfiber
Nanofiber
PHBV
Scaffold
Tissue engineering
Issue Date2007
PublisherTrans Tech Publications Ltd. The Journal's web site is located at http://www.scientific.net
Citation
Key Engineering Materials, 2007, v. 334-335 II, p. 1233-1236 How to Cite?
AbstractPoly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) was used to fabricate micro- and nano-fibrous, non-woven mats by electrospinning for potential tissue engineering applications. The morphology and size of electrospun fibers were assessed systematically by varying the processing parameters. It was found that the diameter of the fibers produced generally increased with electrospinning voltage, needle diameter for the polymer jet and polymer solution concentration. Beaded fibers were readily produced at low PHBV concentrations, whereas the needle was blocked within a very short time during electrospinning when the PHBV concentration was too high. At the polymer concentration of 7.5 % w/v, it was shown that beadless PHBV fibers could be generated continuously by adjusting the electrospinning parameters to appropriate values. This study has clearly demonstrated that electrospinning can be an effective technique to produce PHBV micro- and nano-fibers. It has also been shown that composite fibers containing hydroxyapatite (HA) can be produced using the electrospinning technique.
Persistent Identifierhttp://hdl.handle.net/10722/124877
ISSN
2005 Impact Factor: 0.224
2015 SCImago Journal Rankings: 0.173
References

 

DC FieldValueLanguage
dc.contributor.authorTong, HWen_HK
dc.contributor.authorWang, Men_HK
dc.date.accessioned2010-10-31T10:59:06Z-
dc.date.available2010-10-31T10:59:06Z-
dc.date.issued2007en_HK
dc.identifier.citationKey Engineering Materials, 2007, v. 334-335 II, p. 1233-1236en_HK
dc.identifier.issn1013-9826en_HK
dc.identifier.urihttp://hdl.handle.net/10722/124877-
dc.description.abstractPoly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) was used to fabricate micro- and nano-fibrous, non-woven mats by electrospinning for potential tissue engineering applications. The morphology and size of electrospun fibers were assessed systematically by varying the processing parameters. It was found that the diameter of the fibers produced generally increased with electrospinning voltage, needle diameter for the polymer jet and polymer solution concentration. Beaded fibers were readily produced at low PHBV concentrations, whereas the needle was blocked within a very short time during electrospinning when the PHBV concentration was too high. At the polymer concentration of 7.5 % w/v, it was shown that beadless PHBV fibers could be generated continuously by adjusting the electrospinning parameters to appropriate values. This study has clearly demonstrated that electrospinning can be an effective technique to produce PHBV micro- and nano-fibers. It has also been shown that composite fibers containing hydroxyapatite (HA) can be produced using the electrospinning technique.en_HK
dc.languageengen_HK
dc.publisherTrans Tech Publications Ltd. The Journal's web site is located at http://www.scientific.neten_HK
dc.relation.ispartofKey Engineering Materialsen_HK
dc.subjectElectrospinningen_HK
dc.subjectMicrofiberen_HK
dc.subjectNanofiberen_HK
dc.subjectPHBVen_HK
dc.subjectScaffolden_HK
dc.subjectTissue engineeringen_HK
dc.titleEffects of processing parameters on the morphology and size of electrospun PHBV micro- And nano-fibersen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1013-9826&volume=334-335 &spage=1233&epage=1236&date=2007&atitle=Effects+of+processing+parameters+on+the+morphology+and+size+of+electrospun+PHBV+micro-+and+nano-fibersen_HK
dc.identifier.emailWang, M:memwang@hku.hken_HK
dc.identifier.authorityWang, M=rp00185en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.4028/www.scientific.net/KEM.334-335.1233-
dc.identifier.scopuseid_2-s2.0-33847073799en_HK
dc.identifier.hkuros173093en_HK
dc.identifier.hkuros132984-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33847073799&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume334-335 IIen_HK
dc.identifier.spage1233en_HK
dc.identifier.epage1236en_HK
dc.publisher.placeSwitzerlanden_HK
dc.identifier.scopusauthoridTong, HW=23476100900en_HK
dc.identifier.scopusauthoridWang, M=15749714100en_HK

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