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Article: The Effect of Cultured Autologous Periodontal Ligament Cells on the Healing of Delayed Autotransplanted Dog's Teeth

TitleThe Effect of Cultured Autologous Periodontal Ligament Cells on the Healing of Delayed Autotransplanted Dog's Teeth
Authors
KeywordsDelayed autotransplantation
periodontal ligament
periodontal regeneration
replantation
Issue Date2010
PublisherElsevier Inc. The Journal's web site is located at http://www.jendodon.com
Citation
Journal Of Endodontics, 2010, v. 36 n. 2, p. 264-267 How to Cite?
AbstractIntroduction: The regeneration of the periodontal structure for avulsed teeth extended dry times has been a goal of dentists. The aim of this study was to investigate a new strategy of delayed replantation for avulsed teeth that were not suitable for immediate replantation. Methods: Extracted dog's premolar teeth were maintained in a dry environment for a month after isolation and proliferation of the periodontal ligament (PDL) cells. Then, tooth roots coated with 1 × 106 cultured autologous PDL cells were autotransplanted in artificial sockets created in the mandible. The dogs were sacrificed 60 days after transplantation. Histologic analyses showed that a root-PDL-bone complex was found in all cases of the PDL cell-loaded samples. Results: The new PDL-like connective tissue was located between the alveolar bone and the transplanted roots, with fibers inserting into the newborn cementum on one end and alveolar bone on the other. For the control samples, no PDL-like tissue was found, and ankylosis was commonly observed. Conclusions: The results indicated that cultured autologous PDL cells assist in the re-establishment of periodontal architecture of autotransplanted teeth that is devoid of viable periodontal cells. © 2010 American Association of Endodontists.
Persistent Identifierhttp://hdl.handle.net/10722/124104
ISSN
2015 Impact Factor: 2.904
2015 SCImago Journal Rankings: 1.681
ISI Accession Number ID
Funding AgencyGrant Number
National Natural Science Foundation of China
Funding Information:

Supported by the National Natural Science Foundation of China Grant.

References

 

DC FieldValueLanguage
dc.contributor.authorWang, Yen_HK
dc.contributor.authorCheung, GSpen_HK
dc.contributor.authorXu, Xen_HK
dc.contributor.authorZhao, Sen_HK
dc.contributor.authorZhang, Cen_HK
dc.date.accessioned2010-10-25T04:07:16Z-
dc.date.available2010-10-25T04:07:16Z-
dc.date.issued2010en_HK
dc.identifier.citationJournal Of Endodontics, 2010, v. 36 n. 2, p. 264-267en_HK
dc.identifier.issn0099-2399en_HK
dc.identifier.urihttp://hdl.handle.net/10722/124104-
dc.description.abstractIntroduction: The regeneration of the periodontal structure for avulsed teeth extended dry times has been a goal of dentists. The aim of this study was to investigate a new strategy of delayed replantation for avulsed teeth that were not suitable for immediate replantation. Methods: Extracted dog's premolar teeth were maintained in a dry environment for a month after isolation and proliferation of the periodontal ligament (PDL) cells. Then, tooth roots coated with 1 × 106 cultured autologous PDL cells were autotransplanted in artificial sockets created in the mandible. The dogs were sacrificed 60 days after transplantation. Histologic analyses showed that a root-PDL-bone complex was found in all cases of the PDL cell-loaded samples. Results: The new PDL-like connective tissue was located between the alveolar bone and the transplanted roots, with fibers inserting into the newborn cementum on one end and alveolar bone on the other. For the control samples, no PDL-like tissue was found, and ankylosis was commonly observed. Conclusions: The results indicated that cultured autologous PDL cells assist in the re-establishment of periodontal architecture of autotransplanted teeth that is devoid of viable periodontal cells. © 2010 American Association of Endodontists.en_HK
dc.languageeng-
dc.publisherElsevier Inc. The Journal's web site is located at http://www.jendodon.comen_HK
dc.relation.ispartofJournal of Endodonticsen_HK
dc.rightsThe Journal of Endodontics. Copyright © Elsevier Inc.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectDelayed autotransplantationen_HK
dc.subjectperiodontal ligamenten_HK
dc.subjectperiodontal regenerationen_HK
dc.subjectreplantationen_HK
dc.subject.meshCell Transplantation-
dc.subject.meshGuided Tissue Regeneration, Periodontal - methods-
dc.subject.meshPeriodontal Ligament - cytology - transplantation-
dc.subject.meshTissue Engineering - methods-
dc.subject.meshTooth Replantation - methods-
dc.titleThe Effect of Cultured Autologous Periodontal Ligament Cells on the Healing of Delayed Autotransplanted Dog's Teethen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0099-2399&volume=36&issue=2&spage=264&epage=267&date=2010&atitle=The+effect+of+cultured+autologous+periodontal+ligament+cells+on+the+healing+of+delayed+autotransplanted+dog%27s+teeth-
dc.identifier.emailCheung, GSp:spcheung@hkucc.hku.hken_HK
dc.identifier.emailZhang, C:zhangcf@hku.hken_HK
dc.identifier.authorityCheung, GSp=rp00016en_HK
dc.identifier.authorityZhang, C=rp01408en_HK
dc.description.naturepostprint-
dc.identifier.doi10.1016/j.joen.2009.09.014en_HK
dc.identifier.pmid20113786-
dc.identifier.scopuseid_2-s2.0-74649084040en_HK
dc.identifier.hkuros168827-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-74649084040&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume36en_HK
dc.identifier.issue2en_HK
dc.identifier.spage264en_HK
dc.identifier.epage267en_HK
dc.identifier.eissn1878-3554-
dc.identifier.isiWOS:000279279400014-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridWang, Y=36088313200en_HK
dc.identifier.scopusauthoridCheung, GSp=7005809531en_HK
dc.identifier.scopusauthoridXu, X=36088260400en_HK
dc.identifier.scopusauthoridZhao, S=36088120200en_HK
dc.identifier.scopusauthoridZhang, C=7405494609en_HK

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