Article: Rapid magnetic-mediated solid-phase extraction and pre-concentration of selected endocrine disrupting chemicals in natural waters by poly(divinylbenzene-co-methacrylic acid) coated Fe3O4 core-shell magnetite microspheres for their liquid chromatography-tandem mass spectrometry determination
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- Publisher Website: 10.1016/j.chroma.2009.12.035
- Scopus: eid_2-s2.0-74849139034
- PMID: 20047750
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| Title | Rapid magnetic-mediated solid-phase extraction and pre-concentration of selected endocrine disrupting chemicals in natural waters by poly(divinylbenzene-co-methacrylic acid) coated Fe3O4 core-shell magnetite microspheres for their liquid chromatography-tandem mass spectrometry determination |
|---|---|
| Authors | Li, Q1 Lam, MHW1 Wu, RSS1 Jiang, B2 |
| Keywords | Core-shell microspheres Endocrine disrupting chemicals Estrogen mimics Magnetite microspheres Solid-phase extraction |
| Issue Date | 2010 |
| Publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/chroma |
| Citation | Journal Of Chromatography A, 2010, v. 1217 n. 8, p. 1219-1226 [How to Cite?] DOI: http://dx.doi.org/10.1016/j.chroma.2009.12.035 |
| Abstract | A new Fe3O4/poly(divinylbenzene-co-methacrylic acid) core-shell magnetite microspheric material have been successfully developed as magnetic-mediated solid-phase extraction micro-particle sorbent in dispersion mode (MM-SPE-MP) for the determination of selected estrogenic endocrine disrupting chemicals (EDCs), namely: estrone (E1), 17β-estradiol (E2), estriol (E3), 17α-ethynylestradiol (EE2) and bisphenol-A (BPA), in natural water, via quantification by HPLC tandem mass spectrometry. The magnetite Fe3O4 core of this MM-SPE-MP sorbent was fabricated by a solvothermal approach and the thin layer of amphipolar poly(divinylbenzene-co-methacrylic acid) (pDVB-MAA) coating was established via suspension polymerization. The resultant core-shell MM-SPE-MP sorbent material was characterized by electron microscopy, X-ray diffraction and Fourier-transformed infrared spectroscopy. Particle size distribution of the core-shell microspheres was within the range 300-700 nm in diameter and the thickness of the pDVB-MAA coating was ca. 10 nm. This magnetite microspheric material can be easily dispersed in aqueous samples and retrieved by the application of external magnetic field via a small piece of permanent magnet. The MM-SPE-MP process for the selected estrogenic EDCs involved the dispersion of the core-shell microspheric sorbent in water samples with sonication, followed by magnetic aided retrieval of the sorbent and solvent (methanol) desorption of extracted EDCs for LC-MS/MS analysis. Partition equilibrium for all the selected EDCs onto this MM-SPE-MP sorbent was achieved within 15 min. Recoveries of the EDCs were in ranges of 56-111%. Analytes with smaller KOW value showed relatively lower recovery (and relatively longer equilibration time for partitioning). Method detection limits achieved were found to be 1-36 pg ml-1 (n = 3), while the repeatability was 6-34% (p < 0.05, n = 3). This work demonstrates the usefulness of MM-SPE-MP in the rapid and highly sensitive monitoring of trace organic contaminants in natural waters. © 2009 Elsevier B.V. All rights reserved. |
| ISSN | 0021-9673 2011 Impact Factor: 4.531 2011 SCImago Journal Rankings: 0.323 |
| DOI | http://dx.doi.org/10.1016/j.chroma.2009.12.035 |
| References | References in Scopus |
| dc.contributor.author | Li, Q | ||||||
|---|---|---|---|---|---|---|---|
| dc.contributor.author | Lam, MHW | ||||||
| dc.contributor.author | Wu, RSS | ||||||
| dc.contributor.author | Jiang, B | ||||||
| dc.date.accessioned | 2010-10-15T03:07:44Z | ||||||
| dc.date.available | 2010-10-15T03:07:44Z | ||||||
| dc.date.issued | 2010 | ||||||
| dc.description.abstract | A new Fe3O4/poly(divinylbenzene-co-methacrylic acid) core-shell magnetite microspheric material have been successfully developed as magnetic-mediated solid-phase extraction micro-particle sorbent in dispersion mode (MM-SPE-MP) for the determination of selected estrogenic endocrine disrupting chemicals (EDCs), namely: estrone (E1), 17β-estradiol (E2), estriol (E3), 17α-ethynylestradiol (EE2) and bisphenol-A (BPA), in natural water, via quantification by HPLC tandem mass spectrometry. The magnetite Fe3O4 core of this MM-SPE-MP sorbent was fabricated by a solvothermal approach and the thin layer of amphipolar poly(divinylbenzene-co-methacrylic acid) (pDVB-MAA) coating was established via suspension polymerization. The resultant core-shell MM-SPE-MP sorbent material was characterized by electron microscopy, X-ray diffraction and Fourier-transformed infrared spectroscopy. Particle size distribution of the core-shell microspheres was within the range 300-700 nm in diameter and the thickness of the pDVB-MAA coating was ca. 10 nm. This magnetite microspheric material can be easily dispersed in aqueous samples and retrieved by the application of external magnetic field via a small piece of permanent magnet. The MM-SPE-MP process for the selected estrogenic EDCs involved the dispersion of the core-shell microspheric sorbent in water samples with sonication, followed by magnetic aided retrieval of the sorbent and solvent (methanol) desorption of extracted EDCs for LC-MS/MS analysis. Partition equilibrium for all the selected EDCs onto this MM-SPE-MP sorbent was achieved within 15 min. Recoveries of the EDCs were in ranges of 56-111%. Analytes with smaller KOW value showed relatively lower recovery (and relatively longer equilibration time for partitioning). Method detection limits achieved were found to be 1-36 pg ml-1 (n = 3), while the repeatability was 6-34% (p < 0.05, n = 3). This work demonstrates the usefulness of MM-SPE-MP in the rapid and highly sensitive monitoring of trace organic contaminants in natural waters. © 2009 Elsevier B.V. All rights reserved. | ||||||
| dc.description.nature | Link_to_subscribed_fulltext | ||||||
| dc.identifier.citation | Journal Of Chromatography A, 2010, v. 1217 n. 8, p. 1219-1226 [How to Cite?] DOI: http://dx.doi.org/10.1016/j.chroma.2009.12.035 | ||||||
| dc.identifier.citeulike | 6409784 | ||||||
| dc.identifier.doi | http://dx.doi.org/10.1016/j.chroma.2009.12.035 | ||||||
| dc.identifier.epage | 1226 | ||||||
| dc.identifier.hkuros | 172463 | ||||||
| dc.identifier.isi | WOS:000274953400005
Funding Information: The work described in this paper was Supported by the Areas of Excellence Scheme established under the University Grants Committee of the Hong Kong Special Administrative Region. China (Project no. AoE/P-04/2004) and a grant from Shenzhen-HongKong Innovative Circle of Shenzhen City (Project no 08df-01) | ||||||
| dc.identifier.issn | 0021-9673 2011 Impact Factor: 4.531 2011 SCImago Journal Rankings: 0.323 | ||||||
| dc.identifier.issue | 8 | ||||||
| dc.identifier.openurl | | ||||||
| dc.identifier.pmid | 20047750 | ||||||
| dc.identifier.scopus | eid_2-s2.0-74849139034 | ||||||
| dc.identifier.spage | 1219 | ||||||
| dc.identifier.uri | http://hdl.handle.net/10722/123981 | ||||||
| dc.identifier.volume | 1217 | ||||||
| dc.language | eng | ||||||
| dc.publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/chroma | ||||||
| dc.publisher.place | Netherlands | ||||||
| dc.relation.ispartof | Journal of Chromatography A | ||||||
| dc.relation.references | References in Scopus | ||||||
| dc.rights | Journal of Chromatography A. Copyright © Elsevier BV. | ||||||
| dc.subject | Core-shell microspheres | ||||||
| dc.subject | Endocrine disrupting chemicals | ||||||
| dc.subject | Estrogen mimics | ||||||
| dc.subject | Magnetite microspheres | ||||||
| dc.subject | Solid-phase extraction | ||||||
| dc.title | Rapid magnetic-mediated solid-phase extraction and pre-concentration of selected endocrine disrupting chemicals in natural waters by poly(divinylbenzene-co-methacrylic acid) coated Fe3O4 core-shell magnetite microspheres for their liquid chromatography-tandem mass spectrometry determination | ||||||
| dc.type | Article |
Author Affiliations
- City University of Hong Kong
- null