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Article: Probiotics and gut health: A special focus on liver diseases

TitleProbiotics and gut health: A special focus on liver diseases
Authors
KeywordsBacterial overgrowth
Barrier function
Endotoxin
Ethanol
Gut
Liver
Probiotics
Translocation
Issue Date2010
PublisherBaishideng Publishing Group. The Journal's web site is located at http://www.wjgnet.com/1007-9327/index.htm
Citation
World Journal Of Gastroenterology, 2010, v. 16 n. 4, p. 403-410 How to Cite?
AbstractProbiotic bacteria have well-established beneficial effects in the management of diarrhoeal diseases. Newer evidence suggests that probiotics have the potential to reduce the risk of developing inflammatory bowel diseases and intestinal bacterial overgrowth after gut surgery. In liver health, the main benefits of probiotics might occur through preventing the production and/or uptake of lipopolysaccharides in the gut, and therefore reducing levels of low-grade inflammation. Specific immune stimulation by probiotics through processes involving dendritic cells might also be beneficial to the host immunological status and help prevent pathogen translocation. Hepatic fat metabolism also seems to be influenced by the presence of commensal bacteria, and potentially by probiotics; although the mechanisms by which probiotic might act on the liver are still unclear. However, this might be of major importance in the future because low-grade inflammation, hepatic fat infiltration, and hepatitis might become more prevalent as a result of high fat intake and the increased prevalence of obesity. © 2010 Baishideng. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/123976
ISSN
2015 Impact Factor: 2.787
2015 SCImago Journal Rankings: 1.076
PubMed Central ID
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorGratz, SWen_HK
dc.contributor.authorMykkanen, Hen_HK
dc.contributor.authorElNezami, HSen_HK
dc.date.accessioned2010-10-14T03:15:12Z-
dc.date.available2010-10-14T03:15:12Z-
dc.date.issued2010en_HK
dc.identifier.citationWorld Journal Of Gastroenterology, 2010, v. 16 n. 4, p. 403-410en_HK
dc.identifier.issn1007-9327en_HK
dc.identifier.urihttp://hdl.handle.net/10722/123976-
dc.description.abstractProbiotic bacteria have well-established beneficial effects in the management of diarrhoeal diseases. Newer evidence suggests that probiotics have the potential to reduce the risk of developing inflammatory bowel diseases and intestinal bacterial overgrowth after gut surgery. In liver health, the main benefits of probiotics might occur through preventing the production and/or uptake of lipopolysaccharides in the gut, and therefore reducing levels of low-grade inflammation. Specific immune stimulation by probiotics through processes involving dendritic cells might also be beneficial to the host immunological status and help prevent pathogen translocation. Hepatic fat metabolism also seems to be influenced by the presence of commensal bacteria, and potentially by probiotics; although the mechanisms by which probiotic might act on the liver are still unclear. However, this might be of major importance in the future because low-grade inflammation, hepatic fat infiltration, and hepatitis might become more prevalent as a result of high fat intake and the increased prevalence of obesity. © 2010 Baishideng. All rights reserved.en_HK
dc.languageeng-
dc.publisherBaishideng Publishing Group. The Journal's web site is located at http://www.wjgnet.com/1007-9327/index.htmen_HK
dc.relation.ispartofWorld Journal of Gastroenterologyen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectBacterial overgrowthen_HK
dc.subjectBarrier functionen_HK
dc.subjectEndotoxinen_HK
dc.subjectEthanolen_HK
dc.subjectGuten_HK
dc.subjectLiveren_HK
dc.subjectProbioticsen_HK
dc.subjectTranslocationen_HK
dc.subject.meshGastrointestinal Diseases - drug therapy-
dc.subject.meshHumans-
dc.subject.meshIntestinal Mucosa - drug effects-
dc.subject.meshLiver Diseases - drug therapy-
dc.subject.meshProbiotics - pharmacology - therapeutic use-
dc.titleProbiotics and gut health: A special focus on liver diseasesen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1007-9327&volume=16&issue=4&spage=403&epage=410&date=2010&atitle=Probiotics+and+gut+health:+a+special+focus+on+liver+disease-
dc.identifier.emailElNezami, HS: elnezami@hkucc.hku.hken_HK
dc.identifier.authorityElNezami, HS=rp00694en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.3748/wjg.v16.i4.403en_HK
dc.identifier.pmid20101763-
dc.identifier.pmcidPMC2811790-
dc.identifier.scopuseid_2-s2.0-76149116164en_HK
dc.identifier.hkuros172284-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-76149116164&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume16en_HK
dc.identifier.issue4en_HK
dc.identifier.spage403en_HK
dc.identifier.epage410en_HK
dc.identifier.isiWOS:000274150400001-
dc.publisher.placeChinaen_HK
dc.identifier.scopusauthoridGratz, SW=9242677500en_HK
dc.identifier.scopusauthoridMykkanen, H=7003915985en_HK
dc.identifier.scopusauthoridElNezami, HS=6603690577en_HK

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