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Conference Paper: Transmission disequilibrium tests and imprinting effects tests based on case-parents trios and case-parent pairs
Title | Transmission disequilibrium tests and imprinting effects tests based on case-parents trios and case-parent pairs |
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Authors | |
Issue Date | 2007 |
Citation | Colloquium of Hong Kong Baptist University, Faculty of Science, Department of Mathematics, Hong Kong, 27 April, 2007 How to Cite? |
Abstract | Based on case-parents trios, two statistics POET and TDTI are developed to test for
imprinting and linkage/association, respectively. When only one parent is available, the 1-
TDTI and 1-POET are proposed accordingly. The asymptotic results of the tests are derived.
Simulations are conducted to investigate the validity and other properties of these proposed
statistics. The way to combine case-parents trios and case-parent pairs information in testing
for imprinting and linkage/association is addressed. |
Persistent Identifier | http://hdl.handle.net/10722/110184 |
DC Field | Value | Language |
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dc.contributor.author | Fung, TWK | en_HK |
dc.date.accessioned | 2010-09-26T01:54:51Z | - |
dc.date.available | 2010-09-26T01:54:51Z | - |
dc.date.issued | 2007 | en_HK |
dc.identifier.citation | Colloquium of Hong Kong Baptist University, Faculty of Science, Department of Mathematics, Hong Kong, 27 April, 2007 | - |
dc.identifier.uri | http://hdl.handle.net/10722/110184 | - |
dc.description.abstract | Based on case-parents trios, two statistics POET and TDTI are developed to test for imprinting and linkage/association, respectively. When only one parent is available, the 1- TDTI and 1-POET are proposed accordingly. The asymptotic results of the tests are derived. Simulations are conducted to investigate the validity and other properties of these proposed statistics. The way to combine case-parents trios and case-parent pairs information in testing for imprinting and linkage/association is addressed. | - |
dc.language | eng | en_HK |
dc.relation.ispartof | Colloquium of Hong Kong Baptist University, Faculty of Science, Department of Mathematics | en_HK |
dc.title | Transmission disequilibrium tests and imprinting effects tests based on case-parents trios and case-parent pairs | en_HK |
dc.type | Conference_Paper | en_HK |
dc.identifier.email | Fung, TWK: wingfung@hku.hk | en_HK |
dc.identifier.authority | Fung, TWK=rp00696 | en_HK |
dc.identifier.hkuros | 133716 | en_HK |