Neuroplasticity: Functional reorganization of the human brain

Abstract

OBJECTIVES: Human brain is a dynamic system that allows for experience-dependent functional organization as well as re-or¬ganization or¬ganization. This unique characteristic of the brain enables us to execute goal-oriented behaviors for the successful survival and perpetuation of the human race. METHODS: We present findings of a series of behavioral and functional neuroimaging studies that examined 1) training-induced plasticity in healthy volunteers as well as individuals suffering from congenital sensory depriva¬tion, and 2) the reorganization of neural circuitry for inhibitory control in a patient recovering from a cerebral vascular accident. RESULTS: Via environmental influences and internal neurochemical mechanisms, the brain exercises its potential of organizing itself in such a way that its functions can be maximized. CONCLUSIONS: Findings enable us to understand the longitudinal changes of the brain during learning and the recovery from brain injuries.