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Conference Paper: Patients with preoperative hepatorenal syndrome (HRS) have comparable long-term outcomes after live-donor liver transplantation (LDLT)

TitlePatients with preoperative hepatorenal syndrome (HRS) have comparable long-term outcomes after live-donor liver transplantation (LDLT)
Authors
KeywordsMedical sciences
Gastroenterology medical sciences
Surgery
Issue Date2009
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jtoc/106570021
Citation
The 15th Annual International Congress of the International Liver Transplantation Society, New York City, NY., 8-11 July 2009. In Liver Transplantation, 2009, v. 15 suppl. S7, p. S207, abstract no. P-294 How to Cite?
AbstractBACKGROUND: The aim of this retrospective review was to determine whether preoperative hepatorenal syndrome (HRS) was associated with poor postoperative outcomes after live donor liver transplantation (LDLT). METHODS: A total of 307 adult patients (age≥ 18) who had LDLT done from July 1994 to December 2007 were included in the analysis. The median follow-up period was 55 months. RESULTS: 285 patients received right lobe liver grafts with middle hepatic vein, 2 of the right lobe grafts were without middle hepatic vein. The remaining 20 patients received left lobe liver grafts. 47 patients (15.3%) had preoperative hepatorenal syndrome. There was significantly more patients with pre-operative HRS developed post-operative complications (p=0.006), in which, development of intra-abdominal collection (p=0.001), chest infection (p=0.02) and wound infection (p=0.05) had significantly higher rate when compared to patients without HRS. There was significantly more patients with preoperative HRS died during the hospital stay (p=0.001). Also, median day of stay in Intensive Care Unit (ICU) was significantly longer in patients with HRS (10 days vs. 4 days, p=<0.001).The renal function test was comparable in patients with or without pre-operative HRS at post-operative one year (p=0.079). The overall survival after excluding the hospital mortality did not have statistical significant difference (log-rank test, p= 0.84). CONCLUSION: Patients with HRS had more early postoperative complications and hospital mortality. However, the long term survival outcomes and renal function were not affected by the presence of HRS.
DescriptionThis journal suppl. entitled: Supplement: The International Liver Transplantation Society: 15th Annual International Congress
Poster Session II
Persistent Identifierhttp://hdl.handle.net/10722/108456
ISSN
2015 Impact Factor: 3.951
2015 SCImago Journal Rankings: 1.763

 

DC FieldValueLanguage
dc.contributor.authorChok, KSHen_HK
dc.contributor.authorLo, CMen_HK
dc.contributor.authorNg, KKCen_HK
dc.contributor.authorChan, SCen_HK
dc.date.accessioned2010-09-26T00:40:24Z-
dc.date.available2010-09-26T00:40:24Z-
dc.date.issued2009en_HK
dc.identifier.citationThe 15th Annual International Congress of the International Liver Transplantation Society, New York City, NY., 8-11 July 2009. In Liver Transplantation, 2009, v. 15 suppl. S7, p. S207, abstract no. P-294en_HK
dc.identifier.issn1527-6465-
dc.identifier.urihttp://hdl.handle.net/10722/108456-
dc.descriptionThis journal suppl. entitled: Supplement: The International Liver Transplantation Society: 15th Annual International Congress-
dc.descriptionPoster Session II-
dc.description.abstractBACKGROUND: The aim of this retrospective review was to determine whether preoperative hepatorenal syndrome (HRS) was associated with poor postoperative outcomes after live donor liver transplantation (LDLT). METHODS: A total of 307 adult patients (age≥ 18) who had LDLT done from July 1994 to December 2007 were included in the analysis. The median follow-up period was 55 months. RESULTS: 285 patients received right lobe liver grafts with middle hepatic vein, 2 of the right lobe grafts were without middle hepatic vein. The remaining 20 patients received left lobe liver grafts. 47 patients (15.3%) had preoperative hepatorenal syndrome. There was significantly more patients with pre-operative HRS developed post-operative complications (p=0.006), in which, development of intra-abdominal collection (p=0.001), chest infection (p=0.02) and wound infection (p=0.05) had significantly higher rate when compared to patients without HRS. There was significantly more patients with preoperative HRS died during the hospital stay (p=0.001). Also, median day of stay in Intensive Care Unit (ICU) was significantly longer in patients with HRS (10 days vs. 4 days, p=<0.001).The renal function test was comparable in patients with or without pre-operative HRS at post-operative one year (p=0.079). The overall survival after excluding the hospital mortality did not have statistical significant difference (log-rank test, p= 0.84). CONCLUSION: Patients with HRS had more early postoperative complications and hospital mortality. However, the long term survival outcomes and renal function were not affected by the presence of HRS.-
dc.languageengen_HK
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jtoc/106570021-
dc.relation.ispartofLiver Transplantationen_HK
dc.rightsLiver Transplantation. Copyright © John Wiley & Sons, Inc.-
dc.subjectMedical sciences-
dc.subjectGastroenterology medical sciences-
dc.subjectSurgery-
dc.titlePatients with preoperative hepatorenal syndrome (HRS) have comparable long-term outcomes after live-donor liver transplantation (LDLT)en_HK
dc.typeConference_Paperen_HK
dc.identifier.emailChok, KSH: chok6275@hku.hken_HK
dc.identifier.emailLo, CM: chungmlo@hkucc.hku.hken_HK
dc.identifier.emailNg, KKC: kkcng95@gmail.comen_HK
dc.identifier.emailChan, SC: chanlsc@hku.hk-
dc.identifier.authorityLo, CM=rp00412en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1002/lt.21830-
dc.identifier.hkuros164137en_HK
dc.identifier.hkuros170116-
dc.identifier.hkuros182278-
dc.identifier.volume15en_HK
dc.identifier.issuesuppl. S7en_HK
dc.identifier.spageS207en_HK
dc.identifier.epageS207-
dc.publisher.placeUnited States-
dc.customcontrol.immutablesml 140723-

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