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Conference Paper: Prospective study on donor quality of life before and after right lobe adult-to-adult live donor liver transplantation

TitleProspective study on donor quality of life before and after right lobe adult-to-adult live donor liver transplantation
Authors
Issue Date2004
PublisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JGH
Citation
The 2004 Hong Kong-Shanghai International Liver Congress, The 3rd Scientific Meeting of Cheng Si Yuan (China-International) Hepatic Research Foundation, and The 5th Shanghai International Symposium on Liver Cancer and Hepatitis, Hong Kong, 14-17 February 2004. In Journal of Gastroenterology and Hepatology, 2004, v. 19 n. suppl. 2, p. A171, abstract no. ABS00218 How to Cite?
AbstractINTRODUCTION: Donor right hepatectomy subjects a healthy donor to an ultra-major surgical operation only for the benefit of the recipient. This has become a standard treatment modality to partially relieve the refractory shortage of cadaveric liver grafts. Justification of this procedure ought to be made with the full knowledge of the potential negative effects on the donor. Psychosocial assessment and monitoring of the donor has to be an integral part of such program. To quantify the impact of donor right hepatectomy including the middle hepatic vein on donor quality of life before and after surgery. MATERIALS AND METHODS: Questionnaires with condition specific and generic components were completed by a face-to-face interview by one of the two full-time liver transplantation coordinators before operation, and 1, 2, 3, 6, and 12 months after operation. The generic instrument used was the Chinese (Hong Kong) version of the SF-36 Health Survey. The latter measures eight concepts: physical functioning, physical role, emotional role, social functioning, bodily pain, mental health, vitality, and general health. Condition specific questions were also included. RESULTS: Between December 2002 and November 2003, 30 consecutive donors who underwent donor right hepatectomy including the middle hepatic vein were assessed and monitored prospectively before and after surgery. They were aged 35 years (21 to 56), with male to female ratio of 33.3%:66.7%. The median follow-up was 5.7 months (1.2 to 12). All except 1 were Chinese (1 Indian). All the donors completed the questionnaires on schedule. Donor quality of life before surgery was excellent physically as they were by definition healthy individuals. The worsening was most significant in the 1st to 3rd month post-operatively, especially in physical functioning and bodily pain. These and other psychological aspects returned to the previous levels in 6 months’ time. 86.7% (N=26) of these donors would undergo the same procedure again should there be such a need from the recipient. Donor quality of life was adversely affected immediately following surgery. Return to previous levels could be expected at 6 month. Live donor liver transplantation seems to be acceptable for the rescue of recipients with end-stage liver disease as adverse changes in donor quality of health is temporary.
DescriptionThis journal suppl. entitled: Hong Kong-Shanghai International Liver Congress 2004
Free Paper Abstracts
Persistent Identifierhttp://hdl.handle.net/10722/108448
ISSN
2015 Impact Factor: 3.322
2015 SCImago Journal Rankings: 1.190

 

DC FieldValueLanguage
dc.contributor.authorChan, SC-
dc.contributor.authorLiu, CL-
dc.contributor.authorLo, CM-
dc.contributor.authorFan, ST-
dc.date.accessioned2010-09-26T00:40:04Z-
dc.date.available2010-09-26T00:40:04Z-
dc.date.issued2004-
dc.identifier.citationThe 2004 Hong Kong-Shanghai International Liver Congress, The 3rd Scientific Meeting of Cheng Si Yuan (China-International) Hepatic Research Foundation, and The 5th Shanghai International Symposium on Liver Cancer and Hepatitis, Hong Kong, 14-17 February 2004. In Journal of Gastroenterology and Hepatology, 2004, v. 19 n. suppl. 2, p. A171, abstract no. ABS00218-
dc.identifier.issn0815-9319-
dc.identifier.urihttp://hdl.handle.net/10722/108448-
dc.descriptionThis journal suppl. entitled: Hong Kong-Shanghai International Liver Congress 2004-
dc.descriptionFree Paper Abstracts-
dc.description.abstractINTRODUCTION: Donor right hepatectomy subjects a healthy donor to an ultra-major surgical operation only for the benefit of the recipient. This has become a standard treatment modality to partially relieve the refractory shortage of cadaveric liver grafts. Justification of this procedure ought to be made with the full knowledge of the potential negative effects on the donor. Psychosocial assessment and monitoring of the donor has to be an integral part of such program. To quantify the impact of donor right hepatectomy including the middle hepatic vein on donor quality of life before and after surgery. MATERIALS AND METHODS: Questionnaires with condition specific and generic components were completed by a face-to-face interview by one of the two full-time liver transplantation coordinators before operation, and 1, 2, 3, 6, and 12 months after operation. The generic instrument used was the Chinese (Hong Kong) version of the SF-36 Health Survey. The latter measures eight concepts: physical functioning, physical role, emotional role, social functioning, bodily pain, mental health, vitality, and general health. Condition specific questions were also included. RESULTS: Between December 2002 and November 2003, 30 consecutive donors who underwent donor right hepatectomy including the middle hepatic vein were assessed and monitored prospectively before and after surgery. They were aged 35 years (21 to 56), with male to female ratio of 33.3%:66.7%. The median follow-up was 5.7 months (1.2 to 12). All except 1 were Chinese (1 Indian). All the donors completed the questionnaires on schedule. Donor quality of life before surgery was excellent physically as they were by definition healthy individuals. The worsening was most significant in the 1st to 3rd month post-operatively, especially in physical functioning and bodily pain. These and other psychological aspects returned to the previous levels in 6 months’ time. 86.7% (N=26) of these donors would undergo the same procedure again should there be such a need from the recipient. Donor quality of life was adversely affected immediately following surgery. Return to previous levels could be expected at 6 month. Live donor liver transplantation seems to be acceptable for the rescue of recipients with end-stage liver disease as adverse changes in donor quality of health is temporary.-
dc.languageeng-
dc.publisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JGH-
dc.relation.ispartofJournal of Gastroenterology and Hepatology-
dc.titleProspective study on donor quality of life before and after right lobe adult-to-adult live donor liver transplantation-
dc.typeConference_Paper-
dc.identifier.emailChan, SC: chanlsc@hku.hk-
dc.identifier.emailLiu, CL: clliu@hkucc.hku.hk-
dc.identifier.emailLo, CM: chungmlo@hkucc.hku.hk-
dc.identifier.emailFan, ST: stfan@hku.hk-
dc.identifier.authorityChan, SC=rp01568-
dc.identifier.authorityLo, CM=rp00412-
dc.identifier.authorityFan, ST=rp00355-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1440-1746.2004.abs_2.x-
dc.identifier.hkuros87616-
dc.identifier.volume19-
dc.identifier.issuesuppl. 2-
dc.identifier.spageA171, abstract no. ABS00218-
dc.identifier.epageA171, abstract no. ABS00218-
dc.publisher.placeAustralia-

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