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Conference Paper: Granulin-epithelin precursor modulates chemo-resistance in liver cancer
Title | Granulin-epithelin precursor modulates chemo-resistance in liver cancer |
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Authors | |
Keywords | Medical sciences Oncology |
Issue Date | 2010 |
Publisher | American Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/ |
Citation | The 101st Annual Meeting of the American Association for Cancer Research (AACR 2010), Washington, DC., 17-21 April 2010. In Cancer Research, 2010, v. 70 n. 8 suppl. 1, abstract 2556 How to Cite? |
Abstract | BACKGROUND AND OBJECTIVE: Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and is responsible for 80% of the primary liver tumors in adults. HCC is found to be resistant to most current chemo-therapeutic agents, making the disease as one of the most mortal in the world. There is therefore an urgent demand for better therapeutic approaches. Granulin-epithelin precursor (GEP) was identified as a potential therapeutic target from our genome-wide expression profiles study for HCC. It was an autocrine growth factor with over-expression in most HCCs, and involved in HCCs proliferation, invasion and tumorigenicity. The aim of the ... |
Description | This journal suppl. entitled: Proceedings: AACR 101st Annual Meeting 2010... Poster Presentations - Mechanisms of Resistance 3: Chemotherapeutics: abstract 2556 |
Persistent Identifier | http://hdl.handle.net/10722/107134 |
ISSN | 2023 Impact Factor: 12.5 2023 SCImago Journal Rankings: 3.468 |
DC Field | Value | Language |
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dc.contributor.author | Wong, CL | en_HK |
dc.contributor.author | Cheung, FY | en_HK |
dc.contributor.author | Cheung, ST | en_HK |
dc.date.accessioned | 2010-09-25T23:44:59Z | - |
dc.date.available | 2010-09-25T23:44:59Z | - |
dc.date.issued | 2010 | en_HK |
dc.identifier.citation | The 101st Annual Meeting of the American Association for Cancer Research (AACR 2010), Washington, DC., 17-21 April 2010. In Cancer Research, 2010, v. 70 n. 8 suppl. 1, abstract 2556 | en_HK |
dc.identifier.issn | 0008-5472 | - |
dc.identifier.uri | http://hdl.handle.net/10722/107134 | - |
dc.description | This journal suppl. entitled: Proceedings: AACR 101st Annual Meeting 2010... | - |
dc.description | Poster Presentations - Mechanisms of Resistance 3: Chemotherapeutics: abstract 2556 | - |
dc.description.abstract | BACKGROUND AND OBJECTIVE: Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and is responsible for 80% of the primary liver tumors in adults. HCC is found to be resistant to most current chemo-therapeutic agents, making the disease as one of the most mortal in the world. There is therefore an urgent demand for better therapeutic approaches. Granulin-epithelin precursor (GEP) was identified as a potential therapeutic target from our genome-wide expression profiles study for HCC. It was an autocrine growth factor with over-expression in most HCCs, and involved in HCCs proliferation, invasion and tumorigenicity. The aim of the ... | - |
dc.language | eng | en_HK |
dc.publisher | American Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/ | - |
dc.relation.ispartof | Cancer Research | en_HK |
dc.subject | Medical sciences | - |
dc.subject | Oncology | - |
dc.title | Granulin-epithelin precursor modulates chemo-resistance in liver cancer | en_HK |
dc.type | Conference_Paper | en_HK |
dc.identifier.email | Cheung, FY: cphyllis@hkucc.hku.hk | en_HK |
dc.identifier.email | Cheung, ST: stcheung@hku.hk | en_HK |
dc.identifier.authority | Cheung, ST=rp00457 | en_HK |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.doi | 10.1158/1538-7445.AM10-2556 | - |
dc.identifier.hkuros | 170226 | en_HK |
dc.identifier.volume | 70 | en_HK |
dc.identifier.issue | 8 suppl. 1 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 0008-5472 | - |