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Conference Paper: Discrepant FA reduction between the frontal and parietal lobes of post irradiation medulloblastoma survivors: preliminary findings of regional susceptibility?

TitleDiscrepant FA reduction between the frontal and parietal lobes of post irradiation medulloblastoma survivors: preliminary findings of regional susceptibility?
Authors
Issue Date2006
PublisherThe International Society for Magnetic Resonance in Medicine (ISMRM)
Citation
The International Society for Magnetic Resonance in Medicine (ISMRM) 14th Scientific Meeting & Exhibition, Seattle, WA, 6-12 May 2006 How to Cite?
AbstractIn this study of 16 medulloblastoma survivors and corresponding age-matched control subjects, we tested the hypothesis that fractional anisotropy (FA) in the frontal lobe is more severely reduced than the parietal lobe after whole brain irradiation. Quantitative measurement of regional mean FA was performed using automatically generated masks. We found significant FA reduction in the frontal lobe, but not parietal lobe, in the medulloblastoma survivors compared to controls. Although more severe FA reduction in the frontal lobe was found, this difference did not achieve statistical significance. However, a trend of regional susceptibility of the frontal lobe to radiation was suggested.
Persistent Identifierhttp://hdl.handle.net/10722/105632

 

DC FieldValueLanguage
dc.contributor.authorQiu, Den_HK
dc.contributor.authorLeung, Len_HK
dc.contributor.authorKwong, DLWen_HK
dc.contributor.authorChan, GLHen_HK
dc.contributor.authorCao, Gen_HK
dc.contributor.authorKhong, PLen_HK
dc.date.accessioned2010-09-25T22:42:14Z-
dc.date.available2010-09-25T22:42:14Z-
dc.date.issued2006en_HK
dc.identifier.citationThe International Society for Magnetic Resonance in Medicine (ISMRM) 14th Scientific Meeting & Exhibition, Seattle, WA, 6-12 May 2006-
dc.identifier.urihttp://hdl.handle.net/10722/105632-
dc.description.abstractIn this study of 16 medulloblastoma survivors and corresponding age-matched control subjects, we tested the hypothesis that fractional anisotropy (FA) in the frontal lobe is more severely reduced than the parietal lobe after whole brain irradiation. Quantitative measurement of regional mean FA was performed using automatically generated masks. We found significant FA reduction in the frontal lobe, but not parietal lobe, in the medulloblastoma survivors compared to controls. Although more severe FA reduction in the frontal lobe was found, this difference did not achieve statistical significance. However, a trend of regional susceptibility of the frontal lobe to radiation was suggested.-
dc.languageengen_HK
dc.publisherThe International Society for Magnetic Resonance in Medicine (ISMRM)-
dc.relation.ispartofThe International Society for Magnetic Resonance in Medicine (ISMRM) Scientific Meeting & Exhibitionen_HK
dc.titleDiscrepant FA reduction between the frontal and parietal lobes of post irradiation medulloblastoma survivors: preliminary findings of regional susceptibility?en_HK
dc.typeConference_Paperen_HK
dc.identifier.emailQiu, D: dgiu@hku.hken_HK
dc.identifier.emailKwong, DLW: dlwkwong@hkucc.hku.hken_HK
dc.identifier.emailChan, GLH: chanlh@ha.org.hken_HK
dc.identifier.emailKhong, PL: plkhong@hkucc.hku.hken_HK
dc.identifier.authorityKwong, DLW=rp00414en_HK
dc.identifier.authorityKhong, PL=rp00467en_HK
dc.identifier.hkuros114487en_HK

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