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Conference Paper: Cognitive performance and occupational functioning in first episode schizophrenia: an exploratory study

TitleCognitive performance and occupational functioning in first episode schizophrenia: an exploratory study
Authors
Issue Date2002
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schres
Citation
The 11th Biennial Winter Workshop on Schizophrenia, Davos, Switzerland, 24 February-1 March 2002. In Schizophrenia Research, 2002, v. 53 n. 3 suppl. 1, p. 125, abstract A263 How to Cite?
AbstractThe present study adopted a prospective design to investigate the relationship between neurocognitive performance and occupational functioning in a group of first-episode schizophrenic patients (51 males, 64 females) at 16-month follow-up. The mean age of onset and educational level were 31.8 years (SD = 9.3. and 10.4 years (SD = 3.2), respectively. A set of neurocognitive tests tapping attention (continuous performance test, digit forward span), memory (logical memory, visual reproduction) and executive function (verbal fluency, Wisconsin card sorting test) were implemented to all participants upon discharge and at 16-month interval. Psychotic symptoms and occupational functioning were measured by Positive and Negative Symptoms Scale (PANSS) and “work” sub-scale of Disability Assessment Schedule (DAS). Significant correlations were found between the “work” sub-scale score at 16-month interval and early cognitive function as well as psychotic symptoms: verbal fluency (r = -0.314, p < 0.05), visual reproduction (r = -0.488, p < 0.001), negative symptoms (r = 0.57, p < 0.0005) and total symptoms (0.561, p < 0.0005). Regression analysis further demonstrated that total PANSS score (Beta = 0.46, R2 = 0.33. and visual reproduction (Beta = -0.31, R2 = 0.08) were the only significant predictors of “work” sub-scale of DAS. These findings suggest that although occupational functioning at 16 months could be related to cognitive performance and negative symptom level discharge from the first illness episode.
Persistent Identifierhttp://hdl.handle.net/10722/105386
ISSN
2015 Impact Factor: 4.453
2015 SCImago Journal Rankings: 2.304

 

DC FieldValueLanguage
dc.contributor.authorChen, EYHen_HK
dc.contributor.authorChan, RCKen_HK
dc.contributor.authorTso, Fen_HK
dc.contributor.authorDunn, ELWen_HK
dc.contributor.authorChen, RYLen_HK
dc.contributor.authorChan, WFen_HK
dc.contributor.authorMiao, YKen_HK
dc.contributor.authorYeung, WSen_HK
dc.contributor.authorWong, CKen_HK
dc.contributor.authorTang, OWNen_HK
dc.date.accessioned2010-09-25T22:32:00Z-
dc.date.available2010-09-25T22:32:00Z-
dc.date.issued2002en_HK
dc.identifier.citationThe 11th Biennial Winter Workshop on Schizophrenia, Davos, Switzerland, 24 February-1 March 2002. In Schizophrenia Research, 2002, v. 53 n. 3 suppl. 1, p. 125, abstract A263en_HK
dc.identifier.issn0920-9964en_HK
dc.identifier.urihttp://hdl.handle.net/10722/105386-
dc.description.abstractThe present study adopted a prospective design to investigate the relationship between neurocognitive performance and occupational functioning in a group of first-episode schizophrenic patients (51 males, 64 females) at 16-month follow-up. The mean age of onset and educational level were 31.8 years (SD = 9.3. and 10.4 years (SD = 3.2), respectively. A set of neurocognitive tests tapping attention (continuous performance test, digit forward span), memory (logical memory, visual reproduction) and executive function (verbal fluency, Wisconsin card sorting test) were implemented to all participants upon discharge and at 16-month interval. Psychotic symptoms and occupational functioning were measured by Positive and Negative Symptoms Scale (PANSS) and “work” sub-scale of Disability Assessment Schedule (DAS). Significant correlations were found between the “work” sub-scale score at 16-month interval and early cognitive function as well as psychotic symptoms: verbal fluency (r = -0.314, p < 0.05), visual reproduction (r = -0.488, p < 0.001), negative symptoms (r = 0.57, p < 0.0005) and total symptoms (0.561, p < 0.0005). Regression analysis further demonstrated that total PANSS score (Beta = 0.46, R2 = 0.33. and visual reproduction (Beta = -0.31, R2 = 0.08) were the only significant predictors of “work” sub-scale of DAS. These findings suggest that although occupational functioning at 16 months could be related to cognitive performance and negative symptom level discharge from the first illness episode.-
dc.languageengen_HK
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schresen_HK
dc.relation.ispartofSchizophrenia Researchen_HK
dc.rightsSchizophrenia Research. Copyright © Elsevier BV.en_HK
dc.titleCognitive performance and occupational functioning in first episode schizophrenia: an exploratory studyen_HK
dc.typeConference_Paperen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0920-9964&volume=53&issue=3&spage=125&epage=&date=2002&atitle=Cognitive+performance+and+occupational+functioning+in+first+episode+schizophrenia:+an+exploratory+studyen_HK
dc.identifier.emailChen, EYH: eyhchen@hku.hken_HK
dc.identifier.emailChan, RCK: ckrchan@graduate.hku.hken_HK
dc.identifier.emailDunn, ELW: dunnlw@ha.org.hken_HK
dc.identifier.emailChen, RYL: rylchen@hkucc.hku.hken_HK
dc.identifier.emailChan, WF: chanwf@ha.org.hken_HK
dc.identifier.emailTang, OWN: wntang@ha.org.hken_HK
dc.identifier.doi10.1016/S0920-9964(01)00381-4-
dc.identifier.hkuros73387en_HK
dc.identifier.volume53en_HK
dc.identifier.issue3 suppl. 1en_HK
dc.identifier.spage125, abstract A263en_HK
dc.identifier.epage125, abstract A263-

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