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Conference Paper: Regional brain volume correlations in disorders of neurodevelopment: can we date the onset of pathology?

TitleRegional brain volume correlations in disorders of neurodevelopment: can we date the onset of pathology?
Authors
Issue Date2004
PublisherJohn Wiley & Sons, Inc.
Citation
The 28th International Congress of Psychology (ICP 2004), Beijing, China, 8-13 August 2004. In International Journal of Psychology, 2004, v. 39 n. 5-6, Abstract no. 2028.153 How to Cite?
AbstractNeurodevelopmental disorders have abnormalities across brain networks. Reciprocal afferentation of brain regions established in utero gives mutually trophic support, thus their volumes should positively correlate. We predicted children with autism or ADHD would have disrupted network connectivity reflected by less positive correlation coefficients between regions of grey matter abnormality. This was true for autism, but despite regional grey matter reductions, children with ADHD retained a pattern of positive frontostriatal intercorrelations similar to controls. Therefore initial neuropathology in autism may arise earlier in fetal life than ADHD. The implications for assessing aetiological impact of postnatal events upon each condition are discussed.
Persistent Identifierhttp://hdl.handle.net/10722/105384
ISSN
2015 SCImago Journal Rankings: 0.552

 

DC FieldValueLanguage
dc.contributor.authorMcAlonan, GMen_HK
dc.contributor.authorCheung, Ven_HK
dc.contributor.authorCheung, Cen_HK
dc.contributor.authorHo, TPen_HK
dc.contributor.authorChua, SEen_HK
dc.date.accessioned2010-09-25T22:31:55Z-
dc.date.available2010-09-25T22:31:55Z-
dc.date.issued2004en_HK
dc.identifier.citationThe 28th International Congress of Psychology (ICP 2004), Beijing, China, 8-13 August 2004. In International Journal of Psychology, 2004, v. 39 n. 5-6, Abstract no. 2028.153-
dc.identifier.issn1464-066X-
dc.identifier.urihttp://hdl.handle.net/10722/105384-
dc.description.abstractNeurodevelopmental disorders have abnormalities across brain networks. Reciprocal afferentation of brain regions established in utero gives mutually trophic support, thus their volumes should positively correlate. We predicted children with autism or ADHD would have disrupted network connectivity reflected by less positive correlation coefficients between regions of grey matter abnormality. This was true for autism, but despite regional grey matter reductions, children with ADHD retained a pattern of positive frontostriatal intercorrelations similar to controls. Therefore initial neuropathology in autism may arise earlier in fetal life than ADHD. The implications for assessing aetiological impact of postnatal events upon each condition are discussed.-
dc.languageengen_HK
dc.publisherJohn Wiley & Sons, Inc.-
dc.relation.ispartofInternational Journal of Psychologyen_HK
dc.titleRegional brain volume correlations in disorders of neurodevelopment: can we date the onset of pathology?en_HK
dc.typeConference_Paperen_HK
dc.identifier.emailMcAlonan, GM: mcalonan@hkucc.hku.hken_HK
dc.identifier.emailCheung, V: cheungv@graduate.hku.hken_HK
dc.identifier.emailCheung, C: charlton@hkucc.hku.hken_HK
dc.identifier.emailHo, TP: hrmchtp@hkucc.hku.hken_HK
dc.identifier.emailChua, SE: sechua@hku.hken_HK
dc.identifier.authorityMcAlonan, GM=rp00475en_HK
dc.identifier.authorityChua, SE=rp00438en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1080/00207594.2004.20040810-
dc.identifier.hkuros103850en_HK

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