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Conference Paper: Semantic memory anomaly in first-episode schizophrenia patients

TitleSemantic memory anomaly in first-episode schizophrenia patients
Authors
Issue Date2001
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schres
Citation
Schizophrenia Research, 2001, v. 49 n. 2 suppl., p. 147-148 How to Cite?
AbstractSemantic memory abnormalities in chronic schizophrenia have been studied using a variety of paradigms. Previous studies using a semantic categorization task reported that patients exhibit an extension of the category boundary to semantically related items outside the category. We attempt to replicate the study in a sample of first episode patients. Forty-five first-episode DSM-IV schizophrenic inpatients were assessed at the time of admission (25 of them were medication-naȉve, 20 had received medication for a short period of time). They were assessed again after their symptoms were stabilized with conventional anti-psychotic medication. Compared with normal controls, medication-naȉve patients showed a similar reaction time (RT) profile in the categorization task, ie the borderline condition taking the longest. However, the recently medicated patients showed an increase in RT in the related condition. This increase normalized after the symptoms were controlled by longer treatment with anti-psychotic medication. These findings suggest that semantic memory abnormalities might not be detectable in all patients across different stages in their illness. There is also some suggestion that early changes in semantic system might be reversed by medication.
DescriptionThis journal suppl. contain Abstracts of the ICOSR
Persistent Identifierhttp://hdl.handle.net/10722/105317
ISSN
2015 Impact Factor: 4.453
2015 SCImago Journal Rankings: 2.304

 

DC FieldValueLanguage
dc.contributor.authorWong, AWen_HK
dc.contributor.authorChen, EYHen_HK
dc.date.accessioned2010-09-25T22:29:06Z-
dc.date.available2010-09-25T22:29:06Z-
dc.date.issued2001en_HK
dc.identifier.citationSchizophrenia Research, 2001, v. 49 n. 2 suppl., p. 147-148en_HK
dc.identifier.issn0920-9964en_HK
dc.identifier.urihttp://hdl.handle.net/10722/105317-
dc.descriptionThis journal suppl. contain Abstracts of the ICOSR-
dc.description.abstractSemantic memory abnormalities in chronic schizophrenia have been studied using a variety of paradigms. Previous studies using a semantic categorization task reported that patients exhibit an extension of the category boundary to semantically related items outside the category. We attempt to replicate the study in a sample of first episode patients. Forty-five first-episode DSM-IV schizophrenic inpatients were assessed at the time of admission (25 of them were medication-naȉve, 20 had received medication for a short period of time). They were assessed again after their symptoms were stabilized with conventional anti-psychotic medication. Compared with normal controls, medication-naȉve patients showed a similar reaction time (RT) profile in the categorization task, ie the borderline condition taking the longest. However, the recently medicated patients showed an increase in RT in the related condition. This increase normalized after the symptoms were controlled by longer treatment with anti-psychotic medication. These findings suggest that semantic memory abnormalities might not be detectable in all patients across different stages in their illness. There is also some suggestion that early changes in semantic system might be reversed by medication.-
dc.languageengen_HK
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schresen_HK
dc.relation.ispartofSchizophrenia Researchen_HK
dc.rightsSchizophrenia Research. Copyright © Elsevier BV.en_HK
dc.titleSemantic memory anomaly in first-episode schizophrenia patientsen_HK
dc.typeConference_Paperen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0920-9964&volume=49 &issue=Supplement&spage=147&epage=&date=2001&atitle=Semantic+memory+anomaly+in+first-episode+schizophrenia+patientsen_HK
dc.identifier.emailChen, EYH: eyhchen@hku.hken_HK
dc.identifier.doi10.1016/S0920-9964(01)00159-1-
dc.identifier.hkuros61794en_HK
dc.identifier.volume49en_HK
dc.identifier.issueSupplementen_HK
dc.identifier.issue2 suppl.-
dc.identifier.spage147en_HK

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