File Download

There are no files associated with this item.

Conference Paper: Characterization of low pathogenic H5 subtype influenza viruses from Eurasia: Implications for the origin of highly pathogenic H5N1 viruses

TitleCharacterization of low pathogenic H5 subtype influenza viruses from Eurasia: Implications for the origin of highly pathogenic H5N1 viruses
Authors
Issue Date2007
PublisherInternational Medical Press Ltd.
Citation
The 2007 International Scientific Conference of Options for the Control of Influenza (Options-6), Toronto, ON., Canada, 17-23 June 2007. In Conference Proceedings, 2007, p. 135-138 How to Cite?
AbstractHighly pathogenic avian influenza (HPAI) H5N1 viruses are now endemic in many Asian countries. The immediate precursor of these HPAI viruses was recognized as A/Goose/Guangdong/1/96 (Gs/Gd)-like H5N1 HPAI viruses first detected in Guangdong in 1996. However, precursors of the Gs/GD-like viruses and their subsequent reassortants have not been fully determined. Here we characterize low pathogenic avian influenza (LPAI) H5 subtype viruses isolated from poultry and migratory birds in southern China and Europe from the 1970s to the 2000s. Phylogenetic analyses revealed that Gs/GD-like virus was likely derived from an LPAI H5 virus in migratory birds. However, its variants arose from multiple reassortments between Gs/GD-like virus and viruses from migratory birds, or with those Eurasian viruses isolated in the 1970s. It is of note that unlike HPAI H5N1 viruses, those recent LPAI H5 viruses have not become established in aquatic or terrestrial poultry. Phylogenetic analyses revealed the dynamic nature of the influenza gene pool in Eurasia with repeated transmissions between the eastern and western extremities of the continent. The data also shows reassortment between influenza viruses from domestic and migratory birds in this region that has contributed to the expanded diversity of the influenza gene pool among poultry in Eurasia ...
DescriptionOral Presentations - Genetic and Antigenic Evolution
Persistent Identifierhttp://hdl.handle.net/10722/103171
ISBN

 

DC FieldValueLanguage
dc.contributor.authorDuan, Len_HK
dc.contributor.authorCampitelli, Len_HK
dc.contributor.authorSmith, GJDen_HK
dc.contributor.authorBahl, Jen_HK
dc.contributor.authorDonatelli, Ien_HK
dc.contributor.authorWebster, RGen_HK
dc.contributor.authorShortridge, KFen_HK
dc.contributor.authorPeiris, JSMen_HK
dc.contributor.authorChen, Hen_HK
dc.contributor.authorGuan, Yen_HK
dc.date.accessioned2010-09-25T21:01:07Z-
dc.date.available2010-09-25T21:01:07Z-
dc.date.issued2007en_HK
dc.identifier.citationThe 2007 International Scientific Conference of Options for the Control of Influenza (Options-6), Toronto, ON., Canada, 17-23 June 2007. In Conference Proceedings, 2007, p. 135-138-
dc.identifier.isbn978-1-901-769-15-6-
dc.identifier.urihttp://hdl.handle.net/10722/103171-
dc.descriptionOral Presentations - Genetic and Antigenic Evolution-
dc.description.abstractHighly pathogenic avian influenza (HPAI) H5N1 viruses are now endemic in many Asian countries. The immediate precursor of these HPAI viruses was recognized as A/Goose/Guangdong/1/96 (Gs/Gd)-like H5N1 HPAI viruses first detected in Guangdong in 1996. However, precursors of the Gs/GD-like viruses and their subsequent reassortants have not been fully determined. Here we characterize low pathogenic avian influenza (LPAI) H5 subtype viruses isolated from poultry and migratory birds in southern China and Europe from the 1970s to the 2000s. Phylogenetic analyses revealed that Gs/GD-like virus was likely derived from an LPAI H5 virus in migratory birds. However, its variants arose from multiple reassortments between Gs/GD-like virus and viruses from migratory birds, or with those Eurasian viruses isolated in the 1970s. It is of note that unlike HPAI H5N1 viruses, those recent LPAI H5 viruses have not become established in aquatic or terrestrial poultry. Phylogenetic analyses revealed the dynamic nature of the influenza gene pool in Eurasia with repeated transmissions between the eastern and western extremities of the continent. The data also shows reassortment between influenza viruses from domestic and migratory birds in this region that has contributed to the expanded diversity of the influenza gene pool among poultry in Eurasia ...-
dc.languageengen_HK
dc.publisherInternational Medical Press Ltd.-
dc.relation.ispartofOptions for the Control of Influenza VI: Proceedings of the International Conference on Options for the Control of Influenza VI held in Toronto, Ontario, Canada, June 17-23, 2007en_HK
dc.titleCharacterization of low pathogenic H5 subtype influenza viruses from Eurasia: Implications for the origin of highly pathogenic H5N1 virusesen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailDuan, L: dlhku@hkucc.hku.hken_HK
dc.identifier.emailSmith, GJ: gjsmith@HKUCC.hku.hken_HK
dc.identifier.emailBahl, J: justinbahl@hotmail.comen_HK
dc.identifier.emailWebster, RG: stjude@hkucc.hku.hken_HK
dc.identifier.emailShortridge, KF: microgen@hkucc.hku.hken_HK
dc.identifier.emailPeiris, JSM: malik@hkucc.hku.hken_HK
dc.identifier.emailChen, H: hlchen@hku.hken_HK
dc.identifier.emailGuan, Y: yguan@hkucc.hku.hken_HK
dc.identifier.authoritySmith, GJ=rp00444en_HK
dc.identifier.authorityPeiris, JSM=rp00410en_HK
dc.identifier.authorityChen, H=rp00383en_HK
dc.identifier.authorityGuan, Y=rp00397en_HK
dc.identifier.hkuros132388en_HK
dc.identifier.spage135-
dc.identifier.epage138-
dc.publisher.placeUnited States-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats