File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
  • Find via Find It@HKUL
Supplementary

Conference Paper: Differential in Inter-atrial Dyssynchrony and Atrial Mechanical Function in Sick Sinus Syndrome with or without Paroxysmal Atrial Fibrillation

TitleDifferential in Inter-atrial Dyssynchrony and Atrial Mechanical Function in Sick Sinus Syndrome with or without Paroxysmal Atrial Fibrillation
Authors
Issue Date2007
PublisherAmerican Heart Association, Inc.
Citation
The American Heart Association Scientific Sessions 2007, Orlando, FL, 3-7 November 2007. In Circulation, 2007, v. 116 n. S16, p. II_687-II_688 Abstract no. 3067 How to Cite?
AbstractObjectives: To investigate the intra- and inter-atrial dyssynchrony in pts with sick sinus syndrome (SSS) combined with paroxysmal atrial fibrillation (PAF). Background: Sick sinus syndrome is associated with an increased incidence of atria fibrillation. However, the atrial electromechanical dyssynchrony, structural remodeling, and contraction for SSS combined with PAF are still remained clear. Methods: 30 pts in SSS with or without PAF and normal left ventricular systolic function were included. 19 pts combined with PAF (PAF group) and 11 without history of AF (SSS group) were divided. Doppler echo with tissue Doppler imaging (TDI) was performed from apical 4, 2 and 3 chambers during in sinus rhythm. The peak atrial contraction velocities (Va) and the timing of mechanical events (Ta) were measured at the mid of left atrial (LA) and right atrial free wall (RA). Intra-atrial delay was defined by the standard deviation of Ta among LA sep/lat/inf/ant/post/antsep wall. Inter-atrial delay was defined by the time difference between LA and RA free wall. Results: There were no significant difference in age (73±9 vs.71±9), body surface area, ECG p wave duration, LV ejection fraction, mitral inflow velocities, LA ejection fraction between PAF and SSS groups. LA volume index was increased both in PAF and SSS groups, but there was no difference (42±14 vs.34±15 ml/m2). However, LA active empting fraction was lower in PAF compared to SSS groups (24±14 vs.36±13 %, p=0.027). Mean Va of LA was significantly decreased in PAF group as well (2.6±0.9 vs.3.4±0.9 cm/s, p=0.028). Va of RA was no difference between PAF and SSS groups (4.1±1.5 vs.4.6±2.1 cm/s). Inter-atrial delay was significantly prolonged in PAF compared to SSS groups (33±25 vs.12±19 ms, p=0.022). Neither the standard deviation of Ta nor the maximum difference of Ta among 6 segments of LA showed difference between two groups. Conclusion: In pts with SSS combined with PAF, worsening of LA mechanical contraction and inter-artrial dyssynchrony occurred even in normal left ventricular systolic function. Appropriate atrial pacing for those patients should be considered.
Persistent Identifierhttp://hdl.handle.net/10722/102785
ISSN
2015 Impact Factor: 17.047
2015 SCImago Journal Rankings: 7.853

 

DC FieldValueLanguage
dc.contributor.authorWang, MMen_HK
dc.contributor.authorTse, HFen_HK
dc.contributor.authorLee, KLFen_HK
dc.contributor.authorZhang, Xen_HK
dc.contributor.authorSiu, DCWen_HK
dc.contributor.authorLau, CPen_HK
dc.date.accessioned2010-09-25T20:44:44Z-
dc.date.available2010-09-25T20:44:44Z-
dc.date.issued2007en_HK
dc.identifier.citationThe American Heart Association Scientific Sessions 2007, Orlando, FL, 3-7 November 2007. In Circulation, 2007, v. 116 n. S16, p. II_687-II_688 Abstract no. 3067-
dc.identifier.issn0009-7322-
dc.identifier.urihttp://hdl.handle.net/10722/102785-
dc.description.abstractObjectives: To investigate the intra- and inter-atrial dyssynchrony in pts with sick sinus syndrome (SSS) combined with paroxysmal atrial fibrillation (PAF). Background: Sick sinus syndrome is associated with an increased incidence of atria fibrillation. However, the atrial electromechanical dyssynchrony, structural remodeling, and contraction for SSS combined with PAF are still remained clear. Methods: 30 pts in SSS with or without PAF and normal left ventricular systolic function were included. 19 pts combined with PAF (PAF group) and 11 without history of AF (SSS group) were divided. Doppler echo with tissue Doppler imaging (TDI) was performed from apical 4, 2 and 3 chambers during in sinus rhythm. The peak atrial contraction velocities (Va) and the timing of mechanical events (Ta) were measured at the mid of left atrial (LA) and right atrial free wall (RA). Intra-atrial delay was defined by the standard deviation of Ta among LA sep/lat/inf/ant/post/antsep wall. Inter-atrial delay was defined by the time difference between LA and RA free wall. Results: There were no significant difference in age (73±9 vs.71±9), body surface area, ECG p wave duration, LV ejection fraction, mitral inflow velocities, LA ejection fraction between PAF and SSS groups. LA volume index was increased both in PAF and SSS groups, but there was no difference (42±14 vs.34±15 ml/m2). However, LA active empting fraction was lower in PAF compared to SSS groups (24±14 vs.36±13 %, p=0.027). Mean Va of LA was significantly decreased in PAF group as well (2.6±0.9 vs.3.4±0.9 cm/s, p=0.028). Va of RA was no difference between PAF and SSS groups (4.1±1.5 vs.4.6±2.1 cm/s). Inter-atrial delay was significantly prolonged in PAF compared to SSS groups (33±25 vs.12±19 ms, p=0.022). Neither the standard deviation of Ta nor the maximum difference of Ta among 6 segments of LA showed difference between two groups. Conclusion: In pts with SSS combined with PAF, worsening of LA mechanical contraction and inter-artrial dyssynchrony occurred even in normal left ventricular systolic function. Appropriate atrial pacing for those patients should be considered.-
dc.languageengen_HK
dc.publisherAmerican Heart Association, Inc.-
dc.relation.ispartofCirculationen_HK
dc.titleDifferential in Inter-atrial Dyssynchrony and Atrial Mechanical Function in Sick Sinus Syndrome with or without Paroxysmal Atrial Fibrillationen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailWang, MM: meiwang@hkucc.hku.hken_HK
dc.identifier.emailTse, HF: hftse@hkucc.hku.hken_HK
dc.identifier.emailLee, KLF: klflee@HKUCC.hku.hken_HK
dc.identifier.emailZhang, X: zxuehua@yahoo.comen_HK
dc.identifier.emailSiu, DCW: cwdsiu@hkucc.hku.hken_HK
dc.identifier.emailLau, CP: cplau@hku.hken_HK
dc.identifier.authorityWang, MM=rp00281en_HK
dc.identifier.authorityTse, HF=rp00428en_HK
dc.identifier.authoritySiu, DCW=rp00534en_HK
dc.identifier.hkuros135471en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats