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Conference Paper: Recurrence of atrial fibrillation in hyperthyroidism related atrial fibrillation: a matched case-control study

TitleRecurrence of atrial fibrillation in hyperthyroidism related atrial fibrillation: a matched case-control study
Authors
Issue Date2008
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/heartrhythmjournal
Citation
The 29th Annual Scientific Session of the Heart Rhythm Society (Heart Rhythm 2008), San Francisco, CA., 14-17 May 2008. In Heart Rhythm, v. 5 n. 5 suppl., p. S274, abstract no. PO4-45 How to Cite?
AbstractINTRODUCTION: Although hyperthyroidism related AF usually reverts to sinus rhythm after the return of euthyroid state, whether hyperthyroidism related AF after sinus conversion carries a lower risk of recurrence remains unclear. METHODS: We prospectively studied the AF recurrence rate in 37 hyperthyroid patients with self-terminated AF (48±2 years, male 57%) and 58 hyperthyroid patients with persistent AF converted by electrical cardioversion (57±2 years, male 72%). Age- and sex-matched non-thyroid patients with self-terminated AF and with persistent AF converted by electrical cardioversion were compared. RESULTS: After 29±4 months of follow-up, 14 hyperthyroid patients with self-terminated AF (38%) and 34 hyperthyroid patients with persistent AF converted by electrical cardioversion (59%) developed AF recurrence, which were significantly lower than the non-hyperthyroid controls: 62% (Hazard Ratio (HR): 0.39, 95% confidence interval (CI): 0.18-0.71, P<0.01) and 83% (HR: 0.64, 95% CI: 0.39-0.97, P=0.04) respectively. In Cox regression analysis, only low thyroxine level predicted AF recurrence in hyperthyroid patients with self-terminated AF, whereas long AF duration predicts AF recurrence in hyperthyroid patients with persistent AF. CONCLUSIONS: Hyperthyroidism related AF carries a lower recurrence rate after sinus version. Early electrical cardioversion should be considered in management of hyperthyroid patients with persistent AF.
DescriptionPoster Session 4: no. PO4-45
Persistent Identifierhttp://hdl.handle.net/10722/102293
ISSN
2015 Impact Factor: 4.391
2015 SCImago Journal Rankings: 2.756

 

DC FieldValueLanguage
dc.contributor.authorSiu, DCWen_HK
dc.contributor.authorZhang, Xen_HK
dc.contributor.authorJim, MHen_HK
dc.contributor.authorKung, AWCen_HK
dc.contributor.authorLau, CPen_HK
dc.contributor.authorTse, HFen_HK
dc.date.accessioned2010-09-25T20:24:48Z-
dc.date.available2010-09-25T20:24:48Z-
dc.date.issued2008en_HK
dc.identifier.citationThe 29th Annual Scientific Session of the Heart Rhythm Society (Heart Rhythm 2008), San Francisco, CA., 14-17 May 2008. In Heart Rhythm, v. 5 n. 5 suppl., p. S274, abstract no. PO4-45-
dc.identifier.issn1547-5271-
dc.identifier.urihttp://hdl.handle.net/10722/102293-
dc.descriptionPoster Session 4: no. PO4-45-
dc.description.abstractINTRODUCTION: Although hyperthyroidism related AF usually reverts to sinus rhythm after the return of euthyroid state, whether hyperthyroidism related AF after sinus conversion carries a lower risk of recurrence remains unclear. METHODS: We prospectively studied the AF recurrence rate in 37 hyperthyroid patients with self-terminated AF (48±2 years, male 57%) and 58 hyperthyroid patients with persistent AF converted by electrical cardioversion (57±2 years, male 72%). Age- and sex-matched non-thyroid patients with self-terminated AF and with persistent AF converted by electrical cardioversion were compared. RESULTS: After 29±4 months of follow-up, 14 hyperthyroid patients with self-terminated AF (38%) and 34 hyperthyroid patients with persistent AF converted by electrical cardioversion (59%) developed AF recurrence, which were significantly lower than the non-hyperthyroid controls: 62% (Hazard Ratio (HR): 0.39, 95% confidence interval (CI): 0.18-0.71, P<0.01) and 83% (HR: 0.64, 95% CI: 0.39-0.97, P=0.04) respectively. In Cox regression analysis, only low thyroxine level predicted AF recurrence in hyperthyroid patients with self-terminated AF, whereas long AF duration predicts AF recurrence in hyperthyroid patients with persistent AF. CONCLUSIONS: Hyperthyroidism related AF carries a lower recurrence rate after sinus version. Early electrical cardioversion should be considered in management of hyperthyroid patients with persistent AF.-
dc.languageengen_HK
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/heartrhythmjournal-
dc.relation.ispartofHeart Rhythmen_HK
dc.rightsHeart Rhythm. Copyright © Elsevier Inc.-
dc.titleRecurrence of atrial fibrillation in hyperthyroidism related atrial fibrillation: a matched case-control studyen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailSiu, DCW: cwdsiu@hkucc.hku.hken_HK
dc.identifier.emailZhang, X: zxuehua@yahoo.comen_HK
dc.identifier.emailKung, AWC: awckung@hku.hken_HK
dc.identifier.emailLau, CP: cplau@hku.hken_HK
dc.identifier.emailTse, HF: hftse@hkucc.hku.hken_HK
dc.identifier.authoritySiu, DCW=rp00534en_HK
dc.identifier.authorityKung, AWC=rp00368en_HK
dc.identifier.authorityTse, HF=rp00428en_HK
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.hrthm.2008.03.049-
dc.identifier.hkuros146693en_HK
dc.identifier.hkuros161484-
dc.publisher.placeUnited States-

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