File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Conference Paper: Cryothermal cooled radiofrequency ablation increases lesion size without risk of thrombus formation

TitleCryothermal cooled radiofrequency ablation increases lesion size without risk of thrombus formation
Authors
Issue Date2005
PublisherOxford University Press. The Journal's web site is located at http://eurheartj.oxfordjournals.org/
Citation
The 2005 Congress of the European Society of Cardiology (ESC), Stockholm, Sweden, 3-7 September 2005. In European Heart Journal, 2005, v. 26 suppl. 1, p. 61-62, abstract no. P525 How to Cite?
AbstractSaline irrigation cooling creates larger and deeper radiofrequency (RF) ablation lesions, but is limited by the requirement for an above-freezing temperature of irrigated saline. A cryothermal cooling source may overcome this limitation to increase the lesion dimension and reduce the risk of thrombus formation. METHODS: We compared the lesion dimensions created by 1) RF and 2) salineirrigated RF (SI RF) using a 7 F, 4mm tip electrode catheter, 3) cryoablation (Cryo) and 4) cryothermal cooled RF (Cryo+RF) using a 10 F, 6.5 mm tip electrode catheter and Cryo system (CryoCor, CA) in vertical (V) or horizontal (H) orientiation to a thigh muscle preparation. All 3 modes of RF were delivered for 1 minute at 50W & 60°C, and Cryo was delivered with double-5 minutes freeze-thaw cycles. RESULTS: Of 211 (V=106, H=105) created, SI RF and Cryo+RF created deeper lesion than RF or Cryo application alone (Fig, p< 0.05). In all 4 modes of application, lesions diameter were greater with V than H orientation (Fig, p<0.05). Cryo and Cryo+RF were associated with a significant lower incidence of thrombus formation on the lesions compared with RF and SI RF (0/87vs.26/124, p<0.01). CONCLUSIONS: Cryothermal cooling during RF application resulted in a similar lesion dimension as SI RF. Both Cryo+RF and SI RF created significantly deeper lesions than Cryo, and significantly deeper and larger lesions than RF. The use of Cryo and Cryo+RF were associated with a lower risk of thrombus formation than RF and SI.
Persistent Identifierhttp://hdl.handle.net/10722/102140
ISSN
2015 Impact Factor: 15.064
2015 SCImago Journal Rankings: 6.997

 

DC FieldValueLanguage
dc.contributor.authorTse, HFen_HK
dc.contributor.authorRipley, KLen_HK
dc.contributor.authorZhang, Qen_HK
dc.contributor.authorSiu, CWen_HK
dc.contributor.authorVan Vleet, JFen_HK
dc.contributor.authorLau, CPen_HK
dc.date.accessioned2010-09-25T20:18:39Z-
dc.date.available2010-09-25T20:18:39Z-
dc.date.issued2005en_HK
dc.identifier.citationThe 2005 Congress of the European Society of Cardiology (ESC), Stockholm, Sweden, 3-7 September 2005. In European Heart Journal, 2005, v. 26 suppl. 1, p. 61-62, abstract no. P525-
dc.identifier.issn0195-668Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/102140-
dc.description.abstractSaline irrigation cooling creates larger and deeper radiofrequency (RF) ablation lesions, but is limited by the requirement for an above-freezing temperature of irrigated saline. A cryothermal cooling source may overcome this limitation to increase the lesion dimension and reduce the risk of thrombus formation. METHODS: We compared the lesion dimensions created by 1) RF and 2) salineirrigated RF (SI RF) using a 7 F, 4mm tip electrode catheter, 3) cryoablation (Cryo) and 4) cryothermal cooled RF (Cryo+RF) using a 10 F, 6.5 mm tip electrode catheter and Cryo system (CryoCor, CA) in vertical (V) or horizontal (H) orientiation to a thigh muscle preparation. All 3 modes of RF were delivered for 1 minute at 50W & 60°C, and Cryo was delivered with double-5 minutes freeze-thaw cycles. RESULTS: Of 211 (V=106, H=105) created, SI RF and Cryo+RF created deeper lesion than RF or Cryo application alone (Fig, p< 0.05). In all 4 modes of application, lesions diameter were greater with V than H orientation (Fig, p<0.05). Cryo and Cryo+RF were associated with a significant lower incidence of thrombus formation on the lesions compared with RF and SI RF (0/87vs.26/124, p<0.01). CONCLUSIONS: Cryothermal cooling during RF application resulted in a similar lesion dimension as SI RF. Both Cryo+RF and SI RF created significantly deeper lesions than Cryo, and significantly deeper and larger lesions than RF. The use of Cryo and Cryo+RF were associated with a lower risk of thrombus formation than RF and SI.-
dc.languageengen_HK
dc.publisherOxford University Press. The Journal's web site is located at http://eurheartj.oxfordjournals.org/en_HK
dc.relation.ispartofEuropean Heart Journalen_HK
dc.rightsEuropean Heart Journal. Copyright © Oxford University Press.en_HK
dc.titleCryothermal cooled radiofrequency ablation increases lesion size without risk of thrombus formationen_HK
dc.typeConference_Paperen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0195-668X&volume=&spage=&epage=&date=2005&atitle=Cryothermal+cooled+radiofrequency+ablation+increases+lesion+size+without+without+risk+of+thrombus+formation.en_HK
dc.identifier.emailTse, HF: hftse@hkucc.hku.hken_HK
dc.identifier.emailLau, CP: cplau@hku.hken_HK
dc.identifier.authorityTse, HF=rp00428en_HK
dc.identifier.doi10.1093/eurheartj/26.suppl_1.1-
dc.identifier.hkuros100895en_HK
dc.identifier.volume26-
dc.identifier.issuesuppl. 1-
dc.identifier.spage61, abstract no. P525-
dc.identifier.epage62-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats