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Conference Paper: Effect of calcitriol on bone mineral density (BMD) in Chinese premenopausal women on chronic steroid therapy

TitleEffect of calcitriol on bone mineral density (BMD) in Chinese premenopausal women on chronic steroid therapy
Other TitlesEffect of calcitriol on bone mineral density in Chinese premenopausal women on chronic steroid therapy
Authors
Issue Date2000
PublisherSpringer UK.
Citation
The 2000 World Congress on Osteoporosis, Chicago, IL., 15-18 June 2000. In Osteoporosis International, 2000, v. 11 suppl. 2, p. S183, abstract no. 474 (438) How to Cite?
AbstractThe effect of chronic steroid therapy on BMD in premenopausal women with normal menstrual cycles and its treatment was evaluated in 81 lupus patients. They were randomly allocated to three groups: 1: 0.5mg calcitriol and 1200mg calcium daily, 2: 1200mg calcium and placebo calcitriol and 3: placebo. Baseline T-score at the lumbar spine was > ±1 in 56.8% and 5±2.5 in 3.7% of the patients. At the end of two years, patients in the calcitriol group exhibited a significant increase of 2.1 2.4% in the BMD at the lumbar spine when compared to baseline value (p<0.05). However this change was not significantly different from the respective change in either the calcium (0.4 2.9%) or the placebo group (0.3 3.5%). No significant changes were observed in any of the treatment groups in the BMD at the hip or at the radius. Alkaline phophatase remained stable in the calcitriol group but increased in both the calcium and placebo group. In conclusion, the beneficial effect of calcitriol treatment in these premenopausal women was small, at least when it was instituted late in the course of steroid therapy.
Persistent Identifierhttp://hdl.handle.net/10722/102063
ISSN
2015 Impact Factor: 3.445
2015 SCImago Journal Rankings: 1.460

 

DC FieldValueLanguage
dc.contributor.authorHo, AYY-
dc.contributor.authorLambrinoudaki, I-
dc.contributor.authorChau, DMT-
dc.contributor.authorLau, WCS-
dc.contributor.authorKung, AWC-
dc.date.accessioned2010-09-25T20:15:35Z-
dc.date.available2010-09-25T20:15:35Z-
dc.date.issued2000-
dc.identifier.citationThe 2000 World Congress on Osteoporosis, Chicago, IL., 15-18 June 2000. In Osteoporosis International, 2000, v. 11 suppl. 2, p. S183, abstract no. 474 (438)-
dc.identifier.issn0937-941X-
dc.identifier.urihttp://hdl.handle.net/10722/102063-
dc.description.abstractThe effect of chronic steroid therapy on BMD in premenopausal women with normal menstrual cycles and its treatment was evaluated in 81 lupus patients. They were randomly allocated to three groups: 1: 0.5mg calcitriol and 1200mg calcium daily, 2: 1200mg calcium and placebo calcitriol and 3: placebo. Baseline T-score at the lumbar spine was > ±1 in 56.8% and 5±2.5 in 3.7% of the patients. At the end of two years, patients in the calcitriol group exhibited a significant increase of 2.1 2.4% in the BMD at the lumbar spine when compared to baseline value (p<0.05). However this change was not significantly different from the respective change in either the calcium (0.4 2.9%) or the placebo group (0.3 3.5%). No significant changes were observed in any of the treatment groups in the BMD at the hip or at the radius. Alkaline phophatase remained stable in the calcitriol group but increased in both the calcium and placebo group. In conclusion, the beneficial effect of calcitriol treatment in these premenopausal women was small, at least when it was instituted late in the course of steroid therapy.-
dc.languageeng-
dc.publisherSpringer UK.-
dc.relation.ispartofOsteoporosis International: with other metabolic bone diseases-
dc.rightsThe original publication is available at www.springerlink.com-
dc.titleEffect of calcitriol on bone mineral density (BMD) in Chinese premenopausal women on chronic steroid therapy-
dc.title.alternativeEffect of calcitriol on bone mineral density in Chinese premenopausal women on chronic steroid therapy-
dc.typeConference_Paper-
dc.identifier.emailLau, WCS: cslau@hku.hk-
dc.identifier.emailKung, AWC: awckung@hku.hk-
dc.identifier.authorityLau, WCS=rp01348-
dc.identifier.authorityKung, AWC=rp00368-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s001980070013-
dc.identifier.hkuros51323-
dc.identifier.volume11-
dc.identifier.issuesuppl. 2-
dc.identifier.spageS183, abstract no. 474 (438)-
dc.identifier.epageS183, abstract no. 474 (438)-
dc.publisher.placeUnited Kingdom-

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