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Conference Paper: Nocturnal reflux symptoms correlate with respiratory events in patients with obstructive sleep apnea

TitleNocturnal reflux symptoms correlate with respiratory events in patients with obstructive sleep apnea
Authors
Issue Date2007
PublisherWB Saunders Co. The Journal's web site is located at http://www.elsevier.com/locate/gastro
Citation
Digestive Disease Week and the 108th Annual Meeting of the American Gastroenterological Association Institute, Washington, DC, 19-24 May 2007. In Gastroenterology, 2007, v. 132 n. 4, p. A-482 Abstract no. T1173 How to Cite?
AbstractBackground: Both obstructive sleep apnea (OSA) and gastro-esophageal reflux disease (GERD) are common diseases that share similar risk factors. There have been ongoing controversies regarding the role of gastro-esophageal reflux (GER) in obstructive sleep apnea (OSA). Aims: To determine whether the presence and the severity of GERD is related to the severity of OSA. Methods: Consecutive patients with OSA diagnosed on polysomnography (PSG) (defined as respiratory distress (RDI) index >5) were recruited. Subjects completed a validated GERD questionnaire. The presence and the severity of nocturnal reflux were also assessed. Results: A total of 47 cases were recruited. The median RDI was 17.3 (range 5.1-63.1). The median arousal per hour was 23.5 (range 4.1 to 62.2). BMI positively correlated with RDI (r=0.606, p<0.001) but not with the number of arousals (p=0.201). No correlation was found between the presence of GERD and RDI (p=0.622) or number of arousals per hour (p=0.557). The severity of GERD did not correlate with both RDI (p=0.551) or number of arousals per hour (p=0.451). However, the severity of nocturnal reflux correlated with the number of arousals per hour (r=0.299, p=0.048). The severity of nocturnal reflux was also linked to RDI but it did not reach statistical significance (r= 0.293, p=0.054). Conclusions: This study demonstrated that nocturnal reflux appeared to affect sleep quality and contribute to the severity of sleep apnea. It is possible that the conflicting results of OSA and GERD from the current literature is that the population studied may not all have nocturnal GERD. Further study in this area should focus on patients that complain of nocturnal reflux.
Persistent Identifierhttp://hdl.handle.net/10722/101811
ISSN
2015 Impact Factor: 18.187
2015 SCImago Journal Rankings: 7.170

 

DC FieldValueLanguage
dc.contributor.authorCheung, TKen_HK
dc.contributor.authorLam, Ben_HK
dc.contributor.authorIp, MSMen_HK
dc.contributor.authorWong, YHen_HK
dc.contributor.authorChan, AOOen_HK
dc.contributor.authorLam, SKen_HK
dc.contributor.authorWong, BCYen_HK
dc.date.accessioned2010-09-25T20:05:20Z-
dc.date.available2010-09-25T20:05:20Z-
dc.date.issued2007en_HK
dc.identifier.citationDigestive Disease Week and the 108th Annual Meeting of the American Gastroenterological Association Institute, Washington, DC, 19-24 May 2007. In Gastroenterology, 2007, v. 132 n. 4, p. A-482 Abstract no. T1173en_HK
dc.identifier.issn0016-5085en_HK
dc.identifier.urihttp://hdl.handle.net/10722/101811-
dc.description.abstractBackground: Both obstructive sleep apnea (OSA) and gastro-esophageal reflux disease (GERD) are common diseases that share similar risk factors. There have been ongoing controversies regarding the role of gastro-esophageal reflux (GER) in obstructive sleep apnea (OSA). Aims: To determine whether the presence and the severity of GERD is related to the severity of OSA. Methods: Consecutive patients with OSA diagnosed on polysomnography (PSG) (defined as respiratory distress (RDI) index >5) were recruited. Subjects completed a validated GERD questionnaire. The presence and the severity of nocturnal reflux were also assessed. Results: A total of 47 cases were recruited. The median RDI was 17.3 (range 5.1-63.1). The median arousal per hour was 23.5 (range 4.1 to 62.2). BMI positively correlated with RDI (r=0.606, p<0.001) but not with the number of arousals (p=0.201). No correlation was found between the presence of GERD and RDI (p=0.622) or number of arousals per hour (p=0.557). The severity of GERD did not correlate with both RDI (p=0.551) or number of arousals per hour (p=0.451). However, the severity of nocturnal reflux correlated with the number of arousals per hour (r=0.299, p=0.048). The severity of nocturnal reflux was also linked to RDI but it did not reach statistical significance (r= 0.293, p=0.054). Conclusions: This study demonstrated that nocturnal reflux appeared to affect sleep quality and contribute to the severity of sleep apnea. It is possible that the conflicting results of OSA and GERD from the current literature is that the population studied may not all have nocturnal GERD. Further study in this area should focus on patients that complain of nocturnal reflux.-
dc.languageengen_HK
dc.publisherWB Saunders Co. The Journal's web site is located at http://www.elsevier.com/locate/gastroen_HK
dc.relation.ispartofGastroenterologyen_HK
dc.titleNocturnal reflux symptoms correlate with respiratory events in patients with obstructive sleep apneaen_HK
dc.typeConference_Paperen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0016-5085&volume=132 &issue=4&spage=A482&epage=&date=2007&atitle=Nocturnal+reflux+symptoms+correlate+with+respiratory+events+in+patients+with+obstructive+sleep+apnea.++Digestive+Disease+Week+2007,+Washington+DC,+USA,+19-24+Mayen_HK
dc.identifier.emailCheung, TK: cheungtingkin@yahoo.comen_HK
dc.identifier.emailLam, B: lambing@HKUCC.hku.hken_HK
dc.identifier.emailIp, MSM: msmip@hku.hken_HK
dc.identifier.emailChan, AOO: aoochan@hku.hken_HK
dc.identifier.emailLam, SK: deanmed@hku.hken_HK
dc.identifier.emailWong, BCY: bcywong@hku.hken_HK
dc.identifier.authorityIp, MSM=rp00347en_HK
dc.identifier.authorityWong, BCY=rp00429en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S0016-5085(07)60009-2-
dc.identifier.hkuros130480en_HK
dc.identifier.volume132en_HK
dc.identifier.issue4en_HK
dc.identifier.spage482en_HK

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