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Conference Paper: A comparative study of intense pulse light alone for treatment of facial acne in Asian skin and in combining photodyamic therapy.

TitleA comparative study of intense pulse light alone for treatment of facial acne in Asian skin and in combining photodyamic therapy.
Authors
Issue Date2006
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/34073
Citation
The 26th Annual Meeting of American Society for Laser Medicine and Surgery, Boston, MA., 5-9 April, 2006. In Lasers in Surgery and Medicine, 2006, v. 38 suppl. 18, p. 29, abstract no. 87 How to Cite?
AbstractBACKGROUND AND OBJECTIVES: Skin reaction with intense pulsed light (IPL) on Asian skin often differs from that on Caucasian. This study was to evaluate the reduction of acne using IPL in Asians and any enhanced effects when combining IPL with photodynamic therapy (PDT) using topical 5-aminolevulinic acid (ALA). METHODS: 22 Chinese patients with phototypes IV or V and moderate acne were enrolled for a randomized half facial treatments with IPL, ALA-IPL or controls. All applied adapalene gel 0.1% on the whole face during this period. 20% ALA was applied to half of the face 30 minutes prior to IPL. IPL by the Ellipse Flex system (Danish Dermatologic Development, Denmark) emitting wavelengths of 530–750 nm was used. Patients were treated 4 times at 3-week intervals. Single passes with double pulses with 10 ms delay and pulse duration of 2.5 ms were used. RESULTS: Eighteen patients completed fourth treatment and most had reduction of inflammatory acne that was statistically significant on the ALA-treated side (p?0.025) and control side (p?0.031). Mean reduction in inflammatory lesions was 54.1% after 4 weeks, and 57.7% 12 weeks after treatment in ALA-IPL group while clearance in IPL group were 22.2% after 4 weeks and 41.5% after 12 weeks. However, the control group had the best clearance at 4 week (55.9%) and at 12 week (87.1%) without statistically significant difference between the control and intervention groups. CONCLUSIONS: ALA-PDT combined with IPL using the same settings in Asians was not effective for moderate acne as in Caucasians.
DescriptionSession: Combined PDT/Dermatoplastics
This journal suppl. entitled: Supplement: American Society for Laser Medicine and Surgery, Twenty-Sixth Annual Meeting, Boston, Massachusetts, April 5–April 9, 2006
Persistent Identifierhttp://hdl.handle.net/10722/101735
ISSN
2015 Impact Factor: 2.135
2015 SCImago Journal Rankings: 0.977

 

DC FieldValueLanguage
dc.contributor.authorYeung, CKen_HK
dc.contributor.authorShek, SYNen_HK
dc.contributor.authorYu, CSen_HK
dc.contributor.authorKono, T.en_HK
dc.contributor.authorChan, HHLen_HK
dc.date.accessioned2010-09-25T20:01:43Z-
dc.date.available2010-09-25T20:01:43Z-
dc.date.issued2006en_HK
dc.identifier.citationThe 26th Annual Meeting of American Society for Laser Medicine and Surgery, Boston, MA., 5-9 April, 2006. In Lasers in Surgery and Medicine, 2006, v. 38 suppl. 18, p. 29, abstract no. 87en_HK
dc.identifier.issn0196-8092en_HK
dc.identifier.urihttp://hdl.handle.net/10722/101735-
dc.descriptionSession: Combined PDT/Dermatoplastics-
dc.descriptionThis journal suppl. entitled: Supplement: American Society for Laser Medicine and Surgery, Twenty-Sixth Annual Meeting, Boston, Massachusetts, April 5–April 9, 2006-
dc.description.abstractBACKGROUND AND OBJECTIVES: Skin reaction with intense pulsed light (IPL) on Asian skin often differs from that on Caucasian. This study was to evaluate the reduction of acne using IPL in Asians and any enhanced effects when combining IPL with photodynamic therapy (PDT) using topical 5-aminolevulinic acid (ALA). METHODS: 22 Chinese patients with phototypes IV or V and moderate acne were enrolled for a randomized half facial treatments with IPL, ALA-IPL or controls. All applied adapalene gel 0.1% on the whole face during this period. 20% ALA was applied to half of the face 30 minutes prior to IPL. IPL by the Ellipse Flex system (Danish Dermatologic Development, Denmark) emitting wavelengths of 530–750 nm was used. Patients were treated 4 times at 3-week intervals. Single passes with double pulses with 10 ms delay and pulse duration of 2.5 ms were used. RESULTS: Eighteen patients completed fourth treatment and most had reduction of inflammatory acne that was statistically significant on the ALA-treated side (p?0.025) and control side (p?0.031). Mean reduction in inflammatory lesions was 54.1% after 4 weeks, and 57.7% 12 weeks after treatment in ALA-IPL group while clearance in IPL group were 22.2% after 4 weeks and 41.5% after 12 weeks. However, the control group had the best clearance at 4 week (55.9%) and at 12 week (87.1%) without statistically significant difference between the control and intervention groups. CONCLUSIONS: ALA-PDT combined with IPL using the same settings in Asians was not effective for moderate acne as in Caucasians.-
dc.languageengen_HK
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/34073en_HK
dc.relation.ispartofLasers in Surgery and Medicineen_HK
dc.rightsLasers in Surgery and Medicine. Copyright © John Wiley & Sons, Inc.en_HK
dc.titleA comparative study of intense pulse light alone for treatment of facial acne in Asian skin and in combining photodyamic therapy.en_HK
dc.typeConference_Paperen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0196-8092&volume=S18&spage=87&epage=&date=2006&atitle=A+comparative+study+of+intense+pulse+light+alone+for+treatment+of+facial+acne+in+Asian+skin+and+in+combining+photodyamic+therapy.en_HK
dc.identifier.emailYeung, CK: yk890901@netvigator.comen_HK
dc.identifier.emailShek, SYN: samantha.shek@gmail.comen_HK
dc.identifier.emailYu, CS: carolsyu@hku.hken_HK
dc.identifier.emailChan, HHL: hhlchan@hkucc.hku.hken_HK
dc.identifier.authorityYu, CS=rp00305en_HK
dc.identifier.doi10.1002/lsm.20314-
dc.identifier.hkuros138151en_HK
dc.identifier.volume38en_HK
dc.identifier.issuesuppl. 18-
dc.identifier.spage29, abstract no. 87en_HK
dc.identifier.epage29, abstract no. 87-

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