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Conference Paper: Quantitative ultrasound and vertebral fracture in postmenopausal southern Chinese women

TitleQuantitative ultrasound and vertebral fracture in postmenopausal southern Chinese women
Authors
Issue Date1998
PublisherSpringer-Verlag London Ltd. The Journal's web site is located at http://link.springer.de/link/service/journals/00198/
Citation
The 1998 European Congress on Osteoporosis, Berlin, Germany, 11-15 September 1998. In Osteoporosis International, 1998, v. 8 n. 3 suppl., p. 54, abstract no. P147 How to Cite?
AbstractQuantitative Ultrasound (QUS) has recently been demonstrated to be able to evaluate fracture risk in osteoporotic patients. We evaluated the broadband, ultrasound attenuation (BUA), speed of sound (SOS) and stiffness (Quantitative Ultrasound Index, QUI) in 391 osteoporotic women with recent vertebral fractures using a waterless calcaneal ultrasound system (Sahara, Hologic, USA). Bone mineral density (BMD) at the spine and hip was determined by dual X ray absorptiometry (QDR 2000 plus, Hologic). Their results were compared to a group of 256 non-osteoporotic subjects. After adjustment for age, the relative risk (RR) of vertebral fracture for one standard deviation (SO) reduction was 1.9 (95% confidence interval 1.3-2.5) for BUA, 3.4 (1.9-6.0) for SOS and 1.8 (1.3-2.5) for QUI. A similar relation was observed with BMD at the spine (RR 3.6 (2.0-6.8) and at the hip (RR 2.6 (1.6 - 4.3). Adjustment for spine or hip BMD did not significantly alter the relation between BUA and vertebral fracture. e.g. after adjustment for spinal BMD, the RR of vertebral fracture for 1 SO reduction was 1.6 (1.1-2.4) for BUA, 2.6 (1.4-4.8) for SOS and 1.6 (1.2-2.3) for QUI. In conclusion, the relation between QUS parameters and vertebral fracture is similar to that observed for BMD and vertebral fracture. Our data suggest that QUS is a useful tool in the prediction of vertebral fractures.
Persistent Identifierhttp://hdl.handle.net/10722/101261
ISSN
2015 Impact Factor: 3.445
2015 SCImago Journal Rankings: 1.460

 

DC FieldValueLanguage
dc.contributor.authorKung, AWCen_HK
dc.contributor.authorTang, GWKen_HK
dc.contributor.authorLuk, KDKen_HK
dc.date.accessioned2010-09-25T19:42:25Z-
dc.date.available2010-09-25T19:42:25Z-
dc.date.issued1998en_HK
dc.identifier.citationThe 1998 European Congress on Osteoporosis, Berlin, Germany, 11-15 September 1998. In Osteoporosis International, 1998, v. 8 n. 3 suppl., p. 54, abstract no. P147en_HK
dc.identifier.issn0937-941Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/101261-
dc.description.abstractQuantitative Ultrasound (QUS) has recently been demonstrated to be able to evaluate fracture risk in osteoporotic patients. We evaluated the broadband, ultrasound attenuation (BUA), speed of sound (SOS) and stiffness (Quantitative Ultrasound Index, QUI) in 391 osteoporotic women with recent vertebral fractures using a waterless calcaneal ultrasound system (Sahara, Hologic, USA). Bone mineral density (BMD) at the spine and hip was determined by dual X ray absorptiometry (QDR 2000 plus, Hologic). Their results were compared to a group of 256 non-osteoporotic subjects. After adjustment for age, the relative risk (RR) of vertebral fracture for one standard deviation (SO) reduction was 1.9 (95% confidence interval 1.3-2.5) for BUA, 3.4 (1.9-6.0) for SOS and 1.8 (1.3-2.5) for QUI. A similar relation was observed with BMD at the spine (RR 3.6 (2.0-6.8) and at the hip (RR 2.6 (1.6 - 4.3). Adjustment for spine or hip BMD did not significantly alter the relation between BUA and vertebral fracture. e.g. after adjustment for spinal BMD, the RR of vertebral fracture for 1 SO reduction was 1.6 (1.1-2.4) for BUA, 2.6 (1.4-4.8) for SOS and 1.6 (1.2-2.3) for QUI. In conclusion, the relation between QUS parameters and vertebral fracture is similar to that observed for BMD and vertebral fracture. Our data suggest that QUS is a useful tool in the prediction of vertebral fractures.-
dc.languageengen_HK
dc.publisherSpringer-Verlag London Ltd. The Journal's web site is located at http://link.springer.de/link/service/journals/00198/en_HK
dc.relation.ispartofOsteoporosis Internationalen_HK
dc.titleQuantitative ultrasound and vertebral fracture in postmenopausal southern Chinese womenen_HK
dc.typeConference_Paperen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0937-941X&volume=8 &issue=Suppl 3&spage=P147&epage=&date=1999&atitle=Quantitative+ultrasound+and+vertebral+fracture+in+postmenopausal+southern+Chinese+womenen_HK
dc.identifier.emailKung, AWC: awckung@hku.hken_HK
dc.identifier.emailTang, GWK: gwktang@hkucc.hku.hken_HK
dc.identifier.emailLuk, KDK: hrmoldk@hkucc.hku.hken_HK
dc.identifier.authorityKung, AWC=rp00368en_HK
dc.identifier.authorityTang, GWK=rp00328en_HK
dc.identifier.authorityLuk, KDK=rp00333en_HK
dc.identifier.hkuros41434en_HK
dc.identifier.volume8en_HK
dc.identifier.issue3 suppl.en_HK
dc.identifier.spage54, abstract no. P147en_HK
dc.identifier.epage54, abstract no. P147-

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