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Conference Paper: A computational investigation on the effect of biomechanical factors related to stent-graft models in the thoracic aorta

TitleA computational investigation on the effect of biomechanical factors related to stent-graft models in the thoracic aorta
Authors
Issue Date2007
Citation
Annual International Conference Of The Ieee Engineering In Medicine And Biology - Proceedings, 2007, p. 943-946 How to Cite?
AbstractEndovascular aortic stent-graft is a new, minimally invasive procedure for treating thoracic aortic diseases, and has quickly evolved to be one of the standard treatments subject to anatomic constraints. Stent-graft deployment in the thoracic aorta, especially close to the aortic arch, normally experiences a significant drag force which might lead to the risk of stent-graft failure. A comprehensive investigation on the biomechanical factors affecting the drag force on a stent-graft in the thoracic aorta is thus in order, and the goal here is to perform an in-depth study on the contributing biomechanical factors. Three factors affecting the deployed stent-graft are considered, namely, the internal diameter of the vessel, the starting position of the graft and the diameter of curvature of the aortic arch. Computational fluid dynamic techniques are applied to model the blood flow. The three-dimensional continuity equation and the time-dependent Navier-Stokes equations for an incompressible fluid were solved numerically. The drag force due to the change of momentum within the stent-graft and the shear stress were calculated and analyzed. The drag force on a stent-graft will depend critically on the internal diameter and the starting position of stent-graft deployment. Larger internal diameter leads to larger drag force and the stent-graft deployed at the more distal position may be associated with significantly diminished drag force. Smaller diameter of curvature of the aortic arch results in a decrease of the drag force. These findings may have important implications for the choice and design of stent-grafts in the future. © 2007 IEEE.
Persistent Identifierhttp://hdl.handle.net/10722/100809
ISSN
References

 

DC FieldValueLanguage
dc.contributor.authorLam, SKen_HK
dc.contributor.authorFung, GSKen_HK
dc.contributor.authorCheng, SWKen_HK
dc.contributor.authorChow, KWen_HK
dc.date.accessioned2010-09-25T19:24:24Z-
dc.date.available2010-09-25T19:24:24Z-
dc.date.issued2007en_HK
dc.identifier.citationAnnual International Conference Of The Ieee Engineering In Medicine And Biology - Proceedings, 2007, p. 943-946en_HK
dc.identifier.issn0589-1019en_HK
dc.identifier.urihttp://hdl.handle.net/10722/100809-
dc.description.abstractEndovascular aortic stent-graft is a new, minimally invasive procedure for treating thoracic aortic diseases, and has quickly evolved to be one of the standard treatments subject to anatomic constraints. Stent-graft deployment in the thoracic aorta, especially close to the aortic arch, normally experiences a significant drag force which might lead to the risk of stent-graft failure. A comprehensive investigation on the biomechanical factors affecting the drag force on a stent-graft in the thoracic aorta is thus in order, and the goal here is to perform an in-depth study on the contributing biomechanical factors. Three factors affecting the deployed stent-graft are considered, namely, the internal diameter of the vessel, the starting position of the graft and the diameter of curvature of the aortic arch. Computational fluid dynamic techniques are applied to model the blood flow. The three-dimensional continuity equation and the time-dependent Navier-Stokes equations for an incompressible fluid were solved numerically. The drag force due to the change of momentum within the stent-graft and the shear stress were calculated and analyzed. The drag force on a stent-graft will depend critically on the internal diameter and the starting position of stent-graft deployment. Larger internal diameter leads to larger drag force and the stent-graft deployed at the more distal position may be associated with significantly diminished drag force. Smaller diameter of curvature of the aortic arch results in a decrease of the drag force. These findings may have important implications for the choice and design of stent-grafts in the future. © 2007 IEEE.en_HK
dc.languageengen_HK
dc.relation.ispartofAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedingsen_HK
dc.titleA computational investigation on the effect of biomechanical factors related to stent-graft models in the thoracic aortaen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailCheng, SWK: wkcheng@hkucc.hku.hken_HK
dc.identifier.authorityCheng, SWK=rp00374en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1109/IEMBS.2007.4352447en_HK
dc.identifier.pmid18002113-
dc.identifier.scopuseid_2-s2.0-84926231232en_HK
dc.identifier.hkuros129610en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-57649240565&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.spage943en_HK
dc.identifier.epage946en_HK
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLam, SK=7402279473en_HK
dc.identifier.scopusauthoridFung, GSK=7004213392en_HK
dc.identifier.scopusauthoridCheng, SWK=7404684779en_HK
dc.identifier.scopusauthoridChow, KW=23974180300en_HK

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