Dr Deng, Wen 鄧文
- Psychological stress (induced by intimate partner abuse)
- Cellular aging (focusing on aging modulators: telomere shortening, oxidative stress and inflammation)
- Cancer risk factors (focusing on short telomere profiles and oncological virus infection)
- Mechanisms of genomic instability in cancer and immortalized cells
Dr Wen DENG is currently a Research Assistant Professor in the School of Nursing, The University of Hong Kong (HKU). He is also an Honorary Assistant Professor in Department of Anatomy, HKU. He received his BSc from Department of Physics in Sichuan University and PhD from the Department of Anatomy in HKU. His early career on radiation safety in Sichuan Center for Disease Control and Prevention (previously Sichuan Institute of Occupational Health where he was promoted to Associate Professor) made him interested in radiation biology and DNA damage repair. He was selected as a World Health Organization Fellow by Ministry of Health of the People's Republic of China in 1997 and worked as Research Fellow at Lawrence Livermore National Laboratory, University of California, USA, from 1997 until 2000. He was the first in the world to develop the technique of combined telomere quantitative fluorescence in situ hybridization (Q-FISH) and whole-chromosome painting in human cells. During his PhD study in cancer biology, he was the first to develop the technique of combined telomere Q-FISH and 24-color spectral karyotyping (SKY) in the same human metaphases. This technique has important applications in aging, cancer and telomere biology; and he won the Outstanding Postgraduate Student Award in HKU. He started his new career on cancer and aging in 2005 in HKU. He won Faculty Outstanding Research Output Award in HKU in 2006. He has published about 40 articles in peer-reviewed international journals including Nature Medicine, Proceedings of the National Academy of the Sciences of the United States of America, Cancer Research, and Oncogene. He also has published about 20 Chinese articles in peer-reviewed Chinese national journals.
His current research interests include the relationship between psychological stress (induced by intimate partner abuse) and cellular aging (focusing on aging modulators: telomere shortening, oxidative stress and inflammation), cancer risk factors (focusing on short telomere profiles and oncological virus infection), and mechanisms of genomic instability in cancer and immortalized cells. These areas of research aim to provide insights into cancer and aging intervention or prevention.
|Awardees||Award Date||Honours / Awards / Prizes||Category|
|2006-11-01||Faculty Outstanding Research Output Award: The University of Hong Kong||Research Achievement|
|2006-09-09||Award for Outstanding Research Postgraduate Student (September 2004 - August 2005): The University of Hong Kong||Others|
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