Dr Wang, Xiaoqi 王曉琪
Our research focuses on stem cell and cancer stem cell biology covering from basic to clinical research. Our study, for the first time, demonstrates the presence of the putative hematopoietic stem/progenitor cell (HSPC) population in human adult liver, which opens a new path for understanding of extra-marrow hematopoiesis, liver regeneration, tolerance in organ transplantation, and de novo cancer recurrence in transplantation patients. Moreover,we are the first to raise the concept that human stem cells possess DNA damage checkpoint, which is essential for genomic stability of SC.We then extend the research to potential roles of cell cycle regulators in controllingof pluripotency and differentiation in normal stem cells and liver cancer stem cells, aiming to provide a molecular basis for translating research.
|Awardees||Award Date||Honours / Awards / Prizes||Category|
|2004-02-14||Young Investigator Award, Characterization of LI-Cadherin mutation in HCC (abstract, oral presentation): Hong Kong-Shanghai International Liver Congress, The 3rd Scientific Meeting of Cheng Si Yuan (China-International) Hepatic Research Foundation, and The 5th Shanghai International Symposium on Liver Cancer and Hepatitis, Hong Kong, 14-17 February 2004||Research Achievement|
|2012-01-01||Listed in Who's Who in the World, edition 2012: Who's Who in the World (a directory containing short biographies, published by Marquis Who's Who, an American publisher), edition 2012||Research Achievement|
|2003-07-01||AFLAC Travel Awards, ATR dependent activation of Chk2 and Chk1 (Abstract, oral presentation): American Association of Cancer Research, U.S.A.||Research Achievement|
|2013-04-01||2013 Outstanding Basic Research Paper (Paper titled "Hematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liver"): Department of Surgery, The University of Hong Kong||Research Achievement|
|Term Period||Position||Professional Societies|
|2011-present||member||State Key Laboratory for Liver Research, The University of Hong Kong|
|2/2009-present||full member||The University of Hong Kong Centre for Cancer Research|
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