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Professor Huang, Jiandong 黃建東

Title:
L & T Charitable Foundation Professor in Biomedical Sciences
Professor, Chair of Synthetic Biology
Professor

Department:
School of Biomedical Sciences

Faculty:
Li Ka Shing Faculty of Medicine

Principal Investigator
StatusProject CodeProject TitleAmountFunding Year
 
09202306Functional, phenotypical, and multimodal analysis of the tertiary lymphoid structure (TLS) and TLS B cells as potential novel biomarkers and immunotherapeutic targets for lung cancer 14956922021
 
17127015Characterization of the interaction between Kif5b and NMDAR in ischemic provoked neurodegeneration7931352015
 
HKU 7321/04MFunctions of the ubiquitously expressed kinesin in Purkinje neurons17395002004
 
HKU 767012MRole of kinesin-1 in NMDAR trafficking and cerebral ischemia8500002012
 
HKU 7238/00MMolecular genetic analysis of unconventional myosin 5b (Myo5b): its function and interplay with myosin 5a (Myo5a)7632002000
 
HKU 7188/01MIdentification of myosin VA interacting proteins15138202001
 
08070592Toward a Bioshield against Influenza Virus Infection by Commensal Bacteria Secreting Antiviral Peptide8000002007
 
HKU 785112MGuiding the immune response: a novel approach for HIV-1 vaccine development12000002012
 
HKU 7636/05MRole of kinesin-mediated intracellular transportation in Alzheimer's Disease13609572005
 
HKU 7485/06MTowards a visualized proteome of <I>Escherichia coli</I>14295002006
 
N_HKU 717/99Development of a new method of modifying the mouse genome7000001999
 
HKU 7278/99MMolecular genetic dissection of the function of ubiquitously expressed kinesin and its interaction with myosin VA7755001999
 
N_HKU 712/02DNA recombineering mediated by single stranded oligonucleotides8000002002
 
01030182Helicases as antiviral drug targets8049992003
 
F-HK28/04TDevelopment of an Efficient Recombinant Protein Expression System in Pseudoalteromonas haloplanktis TAC125625002004
 
02040192Determine the functions of the putative metal-binding domain of SARS-CoV helicase8050002004
 
07060572Development of bacteria-mediated oral vaccine against highly pathogenic avian influenza viruses for veterinary use8000002007
 
N_HKU 719/08Toward the treatment of breast cancer by targeting breast tumor initiating cells with microRNAs7120002008
 
HKUST6/CRF/08Protein Trafficking: Mechanism and Diseases2000002008
 
InP/290/09Development of a Pan-organism Riboregulator Device2142002009
 
ITS/148/09Development of a Pan-organism Riboregulator Device9745242009
 
HKU 767110MMechanistic study of the roles of kinesin-1 in myofibril assembly11683782010
 
HKU1/CRF/10Programming the Second Generation Tumor-targeting Bacteria62800002010
 
HKU 767711MQuantitative characterization of mouse embryonic stem cell self- renewal, differentiation and dedifferentiation5600002011
 
HKUST10/CRF/12RProtein Trafficking: Mechanism and Diseases4000002012
 
HKU 768113MNon-canonical role of Kif5b in clathrin uncoating and the endocytic regulation of muscarinic acetylcholine receptors7361282013
 
F-HK704/13TA Generic Mechanism for Pattern Formation: From Theoretical Physics To Synthetic Biology900002013
 
202011033000111Analysis of related factors of early recurrence and late recurrence/non-recurrence of locally advanced gastric cancer12560002020
 
14130742A feasibility study on the inhibition of Staphylococcus aureus infection using AdsA specific antibodies9857602014
 
A-HKU712/14Pattern formation by bacteria: from theoretical physics to synthetic biology19465872014
 
COVID190117Rapid development of anti-SARS-CoV-2 (2019-nCoV) vaccines and exploration of the feasibility of a Pancoronavirus vaccine32026882019
 
17124514Bridge the gap in nerve tissue injury to promote axonal regeneration with fabrication of a bioactive nanofibrous conduit6370052014
 
05162936Investigating the effect of Intracellular Sigma Protein in the treatment of amyotrophic lateral sclerosis and multiple sclerosis9496002017
 
16150422Virus-like particle (VLP)-based mucosal vaccine for inducing cross-serotype immunity against Streptococcus pneumoniae infection11910642016
 
N/AInvestigating the roles of noncoding RNA and arginine methylation in kinesin-mediated cargo transportation in neurons30421402020
 
17124921Characterization of the interactions between NORAD and Kinesin-111357322021
Co-Investigator
StatusProject CodeProject TitleAmountFunding Year
 
CID-HKU1Research for the control of emerging or important acute microbial infections with public health threat to HKSAR280000002020
 
C7147-20GDevelopment of glycopeptide-based anti SARS-CoV-2 vaccines59567432020
 
AoE/M-04/04Developmental genomics and skeletal research809740002003
 
T12-708/12-NFunctional Analyses of How Genomic Variation Affects Personal Risk for Degenerative Skeletal Disorders637500002012
 
GHP/008/06A novel anti-H5N1 avian influenza virus agent using silver nano-particle40000002006
 
T11-709/21-NEcology, molecular virology and pathogenesis of SARSCoV-2: From bedside to bench and back311360002021
 
HKU 7589/05MEvolution, validation and delivery of aptamer-based inhibitors that target the SARS coronavirus9828002005
 
HKU 4/05CGenomic approaches to uncover functionally relevant signalling pathways in craniofacial development65000002005
 
HKU 705007PPolyphosphate metabolic enzymes as potential targets for anti-tuberculosis and general antibiotic drug development5450002007
 
C7034-20EMass cytometry, a multiplexed single-cell technology for chemical biology and precision medicine120000002020
 
N_HKU 711/00Molecular genetic and biochemical analyses of hereditary bone tumours (osteochondromas / exostosis) in Chinese8000002000
 
COVID1903010Preparing for COVID-19 upcoming challenges by clinical and virological investigations335233652021
 
17103618Investigation into high γ -aminobutyric acid producing lactic acid bacteria: insights into genomics, and transcriptomics8692922018
 
HKU 2/01CGenomic approaches to uncover functionally relevant signalling pathways in craniofacial development50000002001
 
HKU 704508PA Molecular toolbox for genetic, proteomic and metabolic engineering in the ethanol-producing bacterium Zymomonas mobilis3437002008
 
17135816Investigating the role of the kinesin motor KIF5B in dendritic mRNA trafficking in neurons12330672016
 
18170512The identification of protective epitopes of a protein vaccine Sta-C9 against Methicillin-resistant Staphylococcus aureus (MRSA) infection and design of a novel multi-epitope vaccine13998322018
 
HKU 1/06CMolecular pathology of liver cancer - a multidisciplinary study64000002006
 
12110962Roles of Epstein-Barr virus-encoded miR-BART microRNAs in viral persistence and transformation of epithelial cells9535922012
 
HKU 704207PChemical and Biochemical Characterization of the Histidine- and Glutamine-rich Protein, Hpn-like: Implications for the Role of Histidine-rich Proteins in Microorganisms5575002007
 
C7037-14GNovel Structure and Function of Human Sirtuins54000002014
 
HKU 7358/04MThe role of neuronal nitric oxide synthase in motoneuron degeneration9399682004
 
03142036Enhancing axonal regeneration of spinal motoneurons after root avulsion by manipulation of chondroitin sulfate proteoglycans (CSPGs)11923762015
 
HKU 1/07CStructure-function of metal-binding proteins in Helicobacter pylori51000002007
 
17102120The role of KIF5B in cue- and location-specific dendritic spine plasticity in fear learning and extinction9962852020
 
HKU 7039/04PCharacterization of a nickel-storage protein Hpn: its relation with bismuth antiulcer drugs2830002004
 
HKU 7393/04MCharacterization of roles of a novel oncogene ALC-1 in the development of hepatocellular carcinoma16367602004
 
HKU 778609MEvolution and functional specialization of alternative promoters in humans8502302009
 
HKU 781008MMolecular characterization of human coronavirus HKU15815412008
 
HKU 779109MGenes get 'recT' : new and improved methods for bacterial DNA engineering9088502009
 
HKU 781509MTranscriptional regulation of multidrug resistance genes by anaerobic adaptation in Escherichia coli11000002009
 
C7103-22GDissecting the pathogenesis of SARS-CoV-2 Omicron and emerging variants61100002022