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Ten Representative Publications
1. Yong KJ, Gao C, Lim JS, Yan B, Yang H, Dimitrov T, Kawasaki A, Ong CW, Wong KF, Lee S, Ravikumar S, Srivastava S, Tian X, Poon RT, Fan ST, Luk JM, Dan YY, Salto-Tellez M, Chai L, Tenen DG. Oncofetal gene SALL4 in aggressive hepatocellular carcinoma. The New England Journal of Medicine. 2013 Jun 13;368(24):2266-76.
2. Sung WK, Zheng H, Li S, Chen R, Liu X, Li Y, Lee NP, Lee WH, Ariyaratne PN, Tennakoon C, Mulawadi FH, Wong KF, Liu AM, Poon RT et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nature Genetics. 2012; 44(7):765-9
3. Lee TK, Murphy SR, Cawley NX, Dhanvantari S, Hewitt ST, Lou H, Lau T, Ma S, Huynh Thanh, Wesley RA, Ng IO, Pacak, Poon RT and Peng Loh. An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers (Corresponding author). Journal of Clinical Investigation 2011. 121:3:880-892 (Impact factor 15.387)
4. Thomas M, Jaffe D, Choti M, Belghiti J, Curley S, Fong Y, Gores G, Kerlan R, Merle P, O'Neil B, Poon RT, Schwartz L, Tepper J, Yao F, Haller D, Mooney M, Venook A. Hepatocellular Carcinoma: Consensus Recommendations of the National Cancer Institute Clinical Trials Planning Meeting. Journal of Clinical Oncology 2010;28(25):3994-4005 (Impact factor 17.793)
5. Pang R, Law WL, Chu ACY, Poon JT, Lam SC, Chow AKM, Ng L, Cheung LW, Lan XR, Lan HY, Tan VPY, Yau TC, Poon RT, Wong BCY. A Subpopulation of CD26+ Cancer Stem Cells with Metastatic Capacity in Human Colorectal Cancer.Cell Stem Cell 2010; 6(6):603-15. (Impact factor 23.563)
6. Wang XQ, Ongkeko WM, Chen L, Yang ZF, Lu P, Chen KK, Lopez JP, Poon RT, and Fan ST. Octamer 4 (Oct4) mediates chemotherapeutic drug resistance in liver cancer cells through a potential a Oct4-AKT-ATP-binding cassette G2 pathway. (Corresponding author). Hepatology 2010; 52(2):528-39. (Impact factor 10.84)
7. Yang ZF, Ho DW, Ng MN, Lau CK, Yu WC, Ngai P, Chu PWK, Lam CT, Poon RT, Fan ST. Significance of CD90+ Cancer Stem Cells in Human Liver Cancer. Cancer Cell 2008;13(2):153-166. (Impact factor 25.288)
8. Ho JWY, Pang RWC, Sun CKW, Yu WC, Fan ST, Poon RTP. Significance of Circulating Endothelial Progenitor Cells in Hepatocellular Carcinoma. (Corresponding author). Hepatology 2006;44:836-843. (Impact factor 10.84)
9. Poon RTP, Ng IOL, Lau C, Yu WC, Yang ZF, Fan ST, Wong J. Tumor Microvessel Density as a Predictor of Recurrence after Resection Hepatocellular Carcinoma: a Prospective Study. (Corresponding author). Journal of Clinical Oncology 2002;20:1775-1785. (Impact factor 17.793)
10. Poon RTP, Fan ST, Lo CM, Liu CL, Ng IOL, Wong J. Long-term Prognosis after Resection of Hepatocellular Carcinoma Complicating Hepatitis B-Related Cirrhosis. (Corresponding author) (awarded “classic paper in gastrointestinal cancer research of the year” by the journal). Journal of Clinical Oncology 2000;18:1094-101. (Impact factor 17.793)
Prof. Ronnie T.P. Poon graduated from the medical school of the University of Hong Kong in 1989 with the award of John Anderson Gold Medal. He also obtained MS & PhD degrees from the University of Hong Kong. He received general surgery residency training at St. Vincent’s Hospital of Sydney, Australia and Queen Mary Hospital, Hong Kong. After completion of residency training, he specialized in hepatobiliary and pancreatic surgery and joined the Department of Surgery of the University of Hong Kong in 1998 as an Assistant Professor. He was promoted to Associate Professor in 1991, Professor of Surgery in 1996 and Chair Professor in 2011. He is the bearer of Suen Chi-Sun Endowed Professorship. He is currently the Chief of the Division of Hepatobiliary and Pancreatic Surgery at Queen Mary Hospital. He has served as Assistant Dean of the Faculty of Medicine from 2001 to 2008.
Prof. Poon’s main clinical and research interest is in hepatobiliary and pancreatic cancers. In particular, he has devoted much of his research effort to improve the outcomes of liver cancer, ranging from surgical resection or ablation for early cancer to molecular targeted therapy for advanced disease. He also has interest in basic research on molecular biology and development of novel therapies for liver cancer. He has published more than 360 original articles in international journals, including papers in top journals such as New England Journal of Medicine, Nature Genetics, Cancer Cell, Cell Stem Cell, Journal of Clinical Oncology, Gastroenterology and Annals of Surgery. His articles are highly cited and for the past consecutive 5 years, he has been among the top 1% scholar according to the ISI Essential Science Indicators. He has also published 15 invited editorials, 17 book chapters and edited two surgical textbooks. He has delivered over 270 invited lectures in international conferences on his research work, including keynote lectures in international conferences such as World Conference on Interventional Oncology and Annual Congress of American Hepato-pancreato-biliary Association. He has contributed to the establishment of consensus guidelines on management of liver cancer by various international organizations, including Asian-Pacific Association for Study of the Liver and National Cancer Institute of the USA. He is the Chairman of the Scientific Committee of the International Hepato-Pancreato-Biliary Association, the Founding Board and Governing Council Member of the International Liver Cancer Association and Executive Secretary of Asia-Pacific Primary Liver Cancer Expert Association. He also serves as the Chairman of Medical Advisory Board for Asian Foundation for Cancer Research.
Prof. Poon has received several awards for his research accomplishment, including the G.B. Ong Traveling Fellowship in 2001, Outstanding Young Researcher Award of the University of Hong Kong in 2003, the International Guest Scholarship of the American College of Surgeons in 2006, Outstanding Researcher Award of the University of Hong Kong 2007 and James IV Traveling Fellowship for 2007. He has served as Chief Editor of Hepatic Oncology, Associate Editor of the World Journal of Surgery, and he also serves in the editorial board of several surgical, gastroenterology and oncology journals including Cancer Therapy, World Journal of Gastroenterology, HBP Surgery, Journal of Gastrointestinal Surgery and Annals of Surgical Oncology.