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Professor Ngan, Elly Sau Wai 顏秀慧

Title:
Professor

Department:

Principal Investigator
StatusProject CodeProject TitleAmountFunding Year
 
17109215Genetic interaction between SUFU, GLI2 and βTrCP in medulloblastoma tumorigenesis9690662015
 
17110818Genetic study on the novel roles of vinculin in enteric and cardiac neural crest cell development and the associated congenital diseases9720002018
 
17111824Delineate the novel roles of Vinculin (Vcl) and pleiotrophin (Ptn) pathway in developing enteric nervous system15595802024
 
HKU 773909MProkineticin signaling in neuroblastoma7557602009
 
HKU 772808MThyroid transcription factor-1 (TTF-1), a potential susceptibility gene for familial papillary thyroid carcinoma15122742008
 
HKU 775710MPremature gliogenesis of enteric neural crest cells induced by aberrant Sonic hedgehog-Notch signalling: a cause of Hirschsprung disease?12000002010
 
01121476Potential use of patient specific induced-pluriopotent stem cell (iPSC) to define genetic lesions contributing to the disease phenotypes of syndromic Hirschsprung (HSCR)9897602013
 
17116914Genetic analysis of interaction between Sufu, Gli and Sox10 in Hedgehog mediated gliogenesis of enteric neural crest cells7482782014
 
17101320Define the core regulomes underlying Hirschsprung pathogenesis using single-cell transcriptomic analysis of human iPSC-derived enteric neural crest9962852020
 
02132396Human stem cell based model for studying neuronal versus glial lineage differentiation of neural crest cells: implication in Hirschsprung disease10000002014
 
07181926Understanding the selective vulnerability of human neurons to PHOX2B polyalanine repeat expansion mutations associated with the congenital central hypoventilation syndrome and Hirschsprung disease15000002019
 
03143236Reading Hedgehog signaling in enteric neural crest cells: implications in Hirschsprung disease12000002015
 
17112416Kinesin family member protein 7 (KIF7) in ciliopathy associated gut motility disorders9610332016
 
06173306Establishment of experiment paradigm for defining functional genetic variants and their epistasis contributing to Hirschsprung (HSCR) disease using human pluripotent stem cells (hPSC)14999702018
 
08192786Analysis of EZH2 mediated neurogenic-to-gliogenic switch in development of enteric neurons and gastrointestinal motility disorders15000002020
 
17108019Potential implications of Hedgehog-mediated metabolic pathways in neural fate acquisition of human neural crest11160192019
 
17107322Vinculin-Yap1-TGFβ signaling in cardiac neural crest cell-mediated valvulogenesis9284382022