Genetic interaction between SUFU, GLI2 and βTrCP in medulloblastoma tumorigenesis


Grant Data
Project Title
Genetic interaction between SUFU, GLI2 and βTrCP in medulloblastoma tumorigenesis
Principal Investigator
Dr Ngan, Elly Sau Wai   (Principal investigator)
Co-Investigator(s)
Professor Hui Chi-Chung   (Co-Investigator)
Duration
36
Start Date
2016-01-01
Completion Date
2018-12-31
Amount
969066
Conference Title
Presentation Title
Keywords
Hedgehog, Medulloblastoma, Gli, Sufu, BTRC
Discipline
Growth and Development
Panel
Biology and Medicine (M)
Sponsor
RGC General Research Fund (GRF)
HKU Project Code
17109215
Grant Type
General Research Fund (GRF)
Funding Year
2015/2016
Status
On-going
Objectives
2 To delineate the molecular mechanism underlying the oncogenic functions of Sufu in MB tumorigenesis to identify potential new therapeutic targets