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Professor Wang, Yu 汪玉

Title:
Professor

Principal Investigator
StatusProject CodeProject TitleAmountFunding Year
 
04151796Selective overexpression of SIRT1 in adipose tissue protects adiponectin deficiency induced liver injury9596082016
 
17124718Endothelial SIRT1 - a key circadian regulator controlling the 24-hour rhythmicity in blood pressure and energy metabolism14861642018
 
HKU 780410MProtective effect of lipocalin-2 deficiency on aging- and dietary obesity-induced endothelial dysfunction14000002010
 
HKU 779712MRole of adipose SIRT1 in regulating systemic energy homeostasis and vascular function: focus on biotin, biotinyl enzymes and lipid metabolism9500002012
 
HKU 777908MMolecular mechanisms underlying the hepato-protective functions of the fat cell-derived hormone adiponectin: potential roles of uncoupling protein 215192842008
 
HKU 781311MVascular protective functions of the anti-aging protein SIRT1 by targeting LKB1/AMPK pathway in endothelial cells: tipping the balance towards vascular homeostasis11200002011
 
HKU 778007MThe potential role of lipocalin-2 as an inflammatory adipokine that links obesity with insulin resistance and metabolic disorders8878632007
 
HKU 780613MHERC2 as a regulator of endothelial senescence by modulating SIRT1/LKB1 signaling axis9526362013
 
17121714Molecular dissection of the pathogenic adipose-vascular signaling axis associated with obesity - focusing on polyamination and deamidation of lipocalin-217317632014
 
17124420Adiponectin-expressing thymic Treg for adoptive immunotherapy in obesity and metabolic diseases9962852020
 
13142651Role of Endothelial SIRT1 in the Prevention of Vascular Ageing - focusing on arterial remodeling and circadian rhythmicity11965682015
 
17153016Timely resetting mitochondrial function by SIRT1 in adipose tissue determines the pace of metabolic ageing in mice13557072016
 
17117017Lipocalin-2: a key mediator of tissue fibrosis in obesity-associated cardiometabolic renal syndrome12254002017
 
08192306SIRT1-mediated vasodilatation: from inside to outside14998002020
 
2399100519Arterial Ageing: from Mechanisms to Applications18000002023
Co-Investigator
StatusProject CodeProject TitleAmountFunding Year
 
AoE/M-707/18Institute of Metabolic Medicine496890002018
 
HKU 2/07CVascular dysfunction in obesity and diabetes: from risk prediction to therapeutic intervention55000002007
 
GHP/027/05Development of a Suspension Antibody Array-based Multiplex Immunoassay for Early Diagnosis and Therapeutic Monitoring of Diabetes and Cardiovascular Diseases28990452005
 
PiH/197/22Development of Adiponectin-based Glycopeptides for Therapeutic Applications9659992021
 
C7037-17WConversion of white into brown adipocytes as a therapeutic strategy for obesity-related metabolic and vascular complications74399962017
 
C7017-18GDevelopment of the glycosylated adiponectin collagenous domain as potential therapeutic agents for cancer and non-alcoholic fatty liver diseases42381302018
 
HKU 779707MAPPL1 as a novel modulator of endothelial nitric oxide production and endothelium-dependent vasodilation12582282007
 
SEG_HKU02High-Performance Tandem Mass Spectrometry Facility for Functional Proteomics and Metabolomics86000002008
 
HKU 7686/06MRedox-mediated posttranscriptional regulation of <I>CHOP</I> expression: its implication in <I>CHOP</I>-mediated pathologies11452002006
 
HKU4/CRF/10A Multi-disciplinary Approach to Investigate Vascular Dysfunction in Obesity and Diabetes: From Molecular Mechanism to Therapeutic Intervention63300002010
 
12111422Novel antifungal small molecule for multi-drug resistant Candida: anti-biofilm activity, in vivo efficacy and cellular targets9353602012
 
PiH/196/22Development of Adiponectin-based Glycopeptides for Therapeutic Applications9659992021
 
17119619Chinese medicine pentacyclic triterpene celastrol ameliorates inflammation, metabolic dysfunctions and insulin resistance in diet-induced obesity via covalently modifying endoplasmic reticulum chaperone GRP789281172019
 
HKU 7624/06MCandida biofilms: molecular mechanisms and clinical implications7325002006
 
06173966The role of bone marrow adipose tissue in glucose tolerance and insulin sensitivity14999002018
 
PiH/195/22Development of Adiponectin-based Glycopeptides for Therapeutic Applications9659992021
 
HKU 768211MEffects of non-invasive remote ischemic preconditioning-induced cardioprotection in Type 1 diabetic rodents: Role of STAT-3 activation9648002011
 
N/ADiscovery and Development of Innovative Antibody Drugs for Metabolic and Cardiovascular Diseases37500002020
 
ITS/134/09FPDiscovery and Pre-Clinical Evaluation of Promising Metal-Based Anti-Cancer Drug Leads89999002009
 
11121651Lipocalin-2 in acute and chronic liver diseases: focusing on neutrophil-mediated innate immune responses7656242013
 
HKU 775912MThe Role of Adipokines in Intervertebral Disc Degeneration of the Lumbar Spine12482502012
 
MRP/048/21XDevelopment of Adiponectin-based Glycopeptides for Therapeutic Applications52991422021
 
C7055-14GA Multi-disciplinary Approach to Investigate Vascular Dysfunction in Obesity and Diabetes: From Molecular Mechanism to Therapeutic Intervention87808502014
 
HKU2/CRF/12RTo Establish a Metabolic Study Centre in Hong Kong: Focusing on the Emerging Metabolic Hormones80000002012
 
13142641Human Prostacyclin Receptors and Endothelial Dysfunction11927362015
 
HKU 782910MThe role of iNOS in ischemic postconditioning cardioprotection in normal and diabetic rodents9798552010
 
HKU 702813PChemical synthesis of the glycosylated adiponectin collagenous domain via serine/threonine ligation4659182013
 
HKU 784011MEffects of Adiponectin on Diabetic Heart Sensitivity to Ischemic Postconditioning: Role of STAT-3 activation10100002011
 
HKU 763312MDoes an elevated lipocalin-2 concentration in plasma lead to endothelial dysfunction and hypertension?11588942012
 
HKU 7522/06MCharacterisation of metallothioneins in marine mussels and gastropods induced by metal and non-metal stressors using proteomics6083962006
 
17100317Plant-derived celastrol ameliorates metabolic dysfunctions, oxidative stress and inflammation in diet-induced obesity via disrupting the cross-talk between PKM2, HIF-1α and IL-1β12290892017
 
HKU 3/CRF/09To Establish a Metabolic Study Center in Hong Kong: Focusing on the liver-derived hormones62000002009
 
HKU 781109MSynergy between N-acetylcysteine, allopurinol and/or PKC-beta inhibition attenuates diabetic cardiomyopathy in the rat7898902009