Role of Smad signalling in the pathogenesis of hypertensive nephropathy and a novel therapeutic potential using ultrasound-microbubble-mediated transfer of inducible Smad7


Grant Data
Project Title
Role of Smad signalling in the pathogenesis of hypertensive nephropathy and a novel therapeutic potential using ultrasound-microbubble-mediated transfer of inducible Smad7
Principal Investigator
Professor Lan, Hui Yao   (Principal investigator)
Duration
28
Start Date
2008-05-01
Completion Date
2010-08-31
Amount
430000
Conference Title
Presentation Title
Keywords
Gene therapy, TGF-beta, Smad7, Hypertension, nephropathy
Discipline
Nephrology/Urology,Gene Regulation
Sponsor
Other projects
Grant Type
Baxter Health Care Ltd. - General Award
Funding Year
2006/2007
Status
On-going
Objectives
To explore the role of TGF-beta/Smad signaling mechanisms in hypertensive nephropathy and develop a novel gene therapy for the hypertensive nephropathy using ultrsound-microbubble-mediated inducible Smad7 strategy.