Role of Smad signalling in the pathogenesis of hypertensive nephropathy and a novel therapeutic potential using ultrasound-microbubble-mediated transfer of inducible Smad7
Professor Lan, Hui Yao (Principal investigator)
Gene therapy, TGF-beta, Smad7, Hypertension, nephropathy
Baxter Health Care Ltd. - General Award
To explore the role of TGF-beta/Smad signaling mechanisms in hypertensive nephropathy and develop a novel gene therapy for the hypertensive nephropathy using ultrsound-microbubble-mediated inducible Smad7 strategy.