Mechanisms of enhanced monocyte binding to vascular endothelium in hyperhomocysteinemia
Dr O, Karmin (Principal investigator)
RGC General Research Fund (GRF)
HKU Project Code
General Research Fund (GRF)
The project aims to investigate the effect of elevated blood homocysteine (Hcy) levels on monocyte binding to aortic endothelium in dietary-induced hyperhomocysteinemic rats as well as the underlying mechanisms. Specifically, efforts will be made to investigate the mechanisms of MCP-1 expression in endothelium and CCR2 expression in peripheral blood moncytes.