Regulation of monocyte chemoattractant protein-1 (MCP-1) expression in atherosclerosis

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Grant Data
Project Title
Regulation of monocyte chemoattractant protein-1 (MCP-1) expression in atherosclerosis
Principal Investigator
Dr O, Karmin   (Principal Investigator)
Duration
36
Start Date
2000-09-01
Amount
763200
Conference Title
Regulation of monocyte chemoattractant protein-1 (MCP-1) expression in atherosclerosis
Presentation Title
Keywords
null
Discipline
N/A
HKU Project Code
HKU 7346/00M
Grant Type
General Research Fund (GRF)
Funding Year
2000
Status
Completed
Objectives
Homocysteinemia (elevated blood levels of homocysteine) is an important risk factor for cardiovascular disorders due to atherosclerosis. The present study aims to investigate the molecular mechanisms of homocysteine stimulation on the MCP-1 expression in endothelial cells, smooth muscle cells, monocytes/macrophages.