A multicenter, open-label study to evaluate simvastatin 20, 40 and 80mg in patients with coronary heart disease
Dr Lee, Kathy Lai Fun (Principal investigator)
Dr Lee (Co-Investigator)
Professor Lau Chu Pak (Co-Investigator)
Other Funding Scheme
Using a titrate-to-goal with simvastatin doses of 20, 40, and 80mg/day, to determine (a) the percent of patients attaining a LDL goal of <= 100mg/dl; (b) the percentchange from baseline for lipid parameters, achieved by this regime; to evaluate the tolerability of simvastatin 20, 40, 80mg in patients with coronary heart disease; to evaluate patient discontinuation rates and patient compliance to different doses.