New avenues in duck immunobiology: the T-cell antigen receptor, lymphoblastoid cell lines, and anti-immunoglobulin-peptide antibodies
Dr Higgins, David Anthony (Principal investigator)
RGC General Research Fund (GRF)
HKU Project Code
General Research Fund (GRF)
To complete the cloning and characterization (already commenced) of the genes encoding the duck T-cell antigen receptor (TcR) polypeptides; to study the genes, products and surface markers of cloned duck T and B lymphoblastoid cells; to raise monoclonal antibodies (MoAbs) to the duck TcRs (using the cloned T cell lines as antigens and targets) and other T cell surface antigens, and to Ig heavy and light chains (using as antigens peptides constructed from deduced amino acid sequences).