New avenues in duck immunobiology: the T-cell antigen receptor, lymphoblastoid cell lines, and anti-immunoglobulin-peptide antibodies


Grant Data
Project Title
New avenues in duck immunobiology: the T-cell antigen receptor, lymphoblastoid cell lines, and anti-immunoglobulin-peptide antibodies
Principal Investigator
Dr Higgins, David Anthony   (Principal investigator)
Duration
24
Start Date
1996-09-01
Completion Date
1998-08-31
Amount
692000
Conference Title
Presentation Title
Sponsor
RGC General Research Fund (GRF)
HKU Project Code
HKU 421/96M
Grant Type
General Research Fund (GRF)
Funding Year
1996/1997
Status
Completed
Objectives
To complete the cloning and characterization (already commenced) of the genes encoding the duck T-cell antigen receptor (TcR) polypeptides; to study the genes, products and surface markers of cloned duck T and B lymphoblastoid cells; to raise monoclonal antibodies (MoAbs) to the duck TcRs (using the cloned T cell lines as antigens and targets) and other T cell surface antigens, and to Ig heavy and light chains (using as antigens peptides constructed from deduced amino acid sequences).